The Evaluation of Therapeutic Efficacy on the Integrated Group Psychotherapy for Patients With Schizophrenia

NCT01139099 | Completed

• 1 other identifier: 201003068R
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Although the patients with schizophrenia can be treated with new generation of antipsychotics medication, additional approaches are necessary to improve schizophrenics' cognitive functions, interpersonal relationships as well as social adjustment. When some of patients return to community, they expose to practical pressure that contribute to worsen and relapse of disease. That further damages patient's cognitive functions. Integrated Psychological Therapy(IPT) on treating schizophrenia has dramatic improvement in recent years; it has formed structured treatment gradually on relieving illusion, hallucination as well as negative symptoms. This study aims at conducting 12-week structured IPT group therapy. The intended subjects are patients, met with DSM-Ⅳ-TR diagnosis of schizophrenia, from community, outpatient and inpatient service. The overall treatments are designed to provide 1-2 hours weekly group therapy which focuses on relieving illusions, hallucination, and negative symptoms. Patients' cognitive functions, ability of emotional adjustment and interpersonal relationship would be evaluated in pre-test and post-test to indicate whether the significant difference exists. There is a controlled group, in which patients who still receive treatment as usual (TAU). The study also compares the evaluation results between IPT group and TAU group, hoping to develop the therapeutic framework for Taiwan people with schizophrenia.

Conditions

Schizophrenia

Outcome Measures

Primary Outcomes (1)

• re-hospitalization rate

  acute symptom relapse and needed to be admitted to the acute ward

  after 3 months of the group psychotherapy

Secondary Outcomes (2)

• Cognitive functions, ability of emotional adjustment, and interpersonal relationship

  12 months of the group tpsychotherapy

• The Positive and Negative Syndrome Scale, Beck depression scale, Beck anxiety scale, Beck suicial ideation scale, Cognitive tests (visual spatial test), CPT-IP for attention test

  12 months of the group psychotherapy

Study Arms (1)

Arm

OTHER

There is no arm in this study.

Behavioral: Group Psychotherapy

Interventions

Group Psychotherapy BEHAVIORAL

integrated group psychotherapy, including the interpersonal and cognitive group therapy

Arm

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• schizophrenia,
• can concentrate in group for 30 minutes.

You may not qualify if:

• substance abuse (alcohol, illegal medication),
• self harm history.

Sponsors & Collaborators

• National Taiwan University Hospital: lead
• Kaohsiung Medical University: collaborator

Study Sites (1)

National Taiwan University Hospital Yun-Lin Branch

Douliu, Taiwan, 64001, Taiwan

Location

MeSH Terms

Conditions

Schizophrenia

Interventions

Psychotherapy, Group

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Socioenvironmental Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Li-Ren Chang, MD

  Department of Psychiatry in National Taiwan University Hospital Yun-Lin Branch

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 7, 2010
• First Posted: June 8, 2010
• Study Start: May 1, 2010
• Primary Completion: May 1, 2011
• Study Completion: May 1, 2011
• Last Updated: December 27, 2012

Record last verified: 2012-11

Locations

TW (1)