A Longitudinal Study to Evaluate the Correlation Between Oculometric Measures and MDS-UPDRS Over Time in a Cohort of Patients With Idiopathic Parkinson's Disease (PD)
Sponsor study identifier
interventional
30
1 country
1
Study Start
May 8, 2023
Actual (reported)Primary Completion
October 28, 2024
Actual (reported)Study Completion
October 28, 2024
Actual (reported)This is a prospective study in a cohort of about 30 patients with Idiopathic Parkinson's disease, who will be evaluated with a clinical assessment and an oculometric examination during a time period with specific intervals. This study aims to evaluate the correlation between oculometric measures and clinical assessment over time.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
October 28, 2024
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 6, 2023
Actual (reported)April 3, 2023
Actual (reported)May 8, 2023
Actual (reported)October 28, 2024
Actual (reported)October 28, 2024
Actual (reported)Change of saccadic latency over time as evaluated during visits
Difference between saccadic latency (ms) as quantified during each visit by the NeuraLight test measured using a statistical comparison of values (e.g. t-test, ANOVA), p\>0.05) over time during study period
12 months
Change of anti-saccadic error rates over time as evaluated during visits
Difference between anti-saccadic error rates (%) as quantified during each visit by the NeuraLight test measured using a statistical comparison of values (e.g. t-test, ANOVA), p\>0.05) over time during study period
12 months
Change of smooth pursuit speed over time as evaluated during visits
Difference between smooth pursuit speed (ms)as quantified during each visit by the NeuraLight test measured using a statistical comparison of values (e.g. t-test, ANOVA), p\>0.05) over time during study period
12 months
Correlation between MDS-UPDRS score and its parts with saccadic latency
The correlation between MDS-UPDRS score and its parts with saccadic latency (ms) measured using R-Square (high correlation\>0.5, moderate correlation 0.2-0.5, low correlation\<0.2), p\<0.05) according to the Movement Disorder Society-Sponsored Unified Parkinson's Disease Rating Scale (MDS-UPDRS) at visits
12 months
Correlation between MDS-UPDRS score and its parts with anti-saccadic error rates
The correlation between MDS-UPDRS score and its parts with anti-saccadic error rates (%), measured using R-Square (high correlation\>0.5, moderate correlation 0.2-0.5, low correlation\<0.2), p\<0.05) according to the Movement Disorder Society-Sponsored Unified Parkinson's Disease Rating Scale (MDS-UPDRS) at visits
12 months
Correlation between MDS-UPDRS score and its parts with smooth pursuit
The correlation between MDS-UPDRS score and its parts with smooth pursuit speed (ms) measured using R-Square (high correlation\>0.5, moderate correlation 0.2-0.5, low correlation\<0.2), p\<0.05) according to the Movement Disorder Society-Sponsored Unified Parkinson's Disease Rating Scale (MDS-UPDRS) at visits
12 months
Using the retrieved data of collected NeuraLight oculometric measures for calibration of prediction models of MDS-UPDRS clinical endpoint
12 months
Men and women with idiopathic PD (Hoehn \& Yahr scale 1-3) aged 18-85 years
NeuraLight software-based platform
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Movement Disorders Unit, Sourasky Tel Aviv Medical Center
Tel Aviv, 6423906, Israel
Tanya Gurevich, MD
Tel Aviv Medical Center
30 participants (actual enrollment reported by the registry).
First Submitted
March 6, 2023
First Posted
April 3, 2023
Study Start
May 8, 2023
Actual (reported)Contact the study team to confirm eligibility.
Primary Completion
October 28, 2024
Actual (reported)Study Completion
October 28, 2024
Actual (reported)Last Updated
October 29, 2024
Record last verified: 2024-10
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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