Added Diagnostic Value of Point of Care Ultrasound in Acute Dyspnea

NCT05782478 | Recruiting

• 1 other identifier: 2022-02789-01
• Study Type: observational
• Target: 160
• Locations: 1 country
• Sites: 2

Brief Summary

Dyspnea is a common diagnostic challenge in the Emergency Department (ED). Delay in diagnosis will increase time to correct treatment and could impact outcome. Previous studies have shown excellent diagnostic performance of point of care ultrasound (POCUS) to detect and differentiate between several important diagnosis (e.g heart failure and pneumonia) in patients with dyspnea. However, in most studies POCUS is performed by physicians highly experienced in ultrasound and often studies have focused only on one or few diagnoses. The aim of this study is to compare the diagnostic accuracy of different diagnosis in dyspnoeic patients before and after a ED physician with limited training applies POCUS.

Conditions

Dyspnea; Hypoxia

Keywords

Ultrasound; Point of care ultrasound

Outcome Measures

Primary Outcomes (1)

• Discharge diagnosis

  Any of the following diagnosis: Decompensated heart failure, pulmonary embolism, COPD exacerbation, asthma exacerbation, bacterial pneumonia, viral pneumonia, pleural fluid, pericardial fluid

  Final diagnosis at index visit discharge

Interventions

Point of care Ultrasound according to study protocol DIAGNOSTIC_TEST

An emergency medicine specialist or resident will according to a structured protocol perform a structured ultrasound examination of the heart, the inferior vena cava and the lungs.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult patients presenting to the Emergency Department at Skåne University Hospital in Lund or Helsingborg Hospital, Sweden.

You may qualify if:

• Adult patients presenting to the Emergency Department within the highest or second highest triage category and any of the following
• Presenting with shortness of breath
• Oxygen saturation less than 90 % on room air
• Respiratory rate more than 25 breaths per minute and oxygen saturation less than 95 % on room air

You may not qualify if:

• Patient is discharge from the Emergency Department (without hospital admission)

Sponsors & Collaborators

• Region Skane: lead

Study Sites (2)

Department of Emergency Medicine, Helsingborg Hospital

Helsingborg, Skåne County, Sweden

RECRUITING

Department of Emergency Medicine, Skåne University Hospital

Lund, Skåne County, Sweden

RECRUITING

MeSH Terms

Conditions

Dyspnea; Hypoxia

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Jakob Lundager Forberg, PhD,MD

  Region Skåne Sweden

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jakob Lundager Forberg, PhD,MD

CONTACT

0046424061000; jakob.lundager-forberg@skane.se

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 8, 2023
• First Posted: March 23, 2023
• Study Start: March 9, 2023
• Primary Completion: January 31, 2026
• Study Completion: March 28, 2026
• Last Updated: July 16, 2025

Record last verified: 2025-06

Locations

SE (2)