Diagnostic Performance of Chest Computed Tomography Scan in Patients Aged 65 and Over Presenting to Emergency Room With Acute Dyspnea
CT-Dys
1 other identifier
interventional
240
1 country
1
Brief Summary
In acute dyspnea, the use of chest radiography is frequent and not very contributive, especially in the elderly patients. However, early diagnosis of the cause of dyspnea in the ED is associated with a better prognosis, in particular for the identification of an infectious or cardiac origin. Chest CT has already shown better diagnostic performances than conventional radiography in several pathologies such as low respiratory infection, and the development of so-called "low dose" scans allows to limit the irradiation during this examination. The investigators aim to conduct a diagnostic study comparing non-injected chest CT-scan and conventional chest radiography in patients older than 65 presenting in the ED with acute dyspnea to assess whether CT-scan improves diagnosis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Dec 2023
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 20, 2023
CompletedFirst Posted
Study publicly available on registry
October 27, 2023
CompletedStudy Start
First participant enrolled
December 1, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2024
CompletedOctober 27, 2023
October 1, 2023
10 months
October 20, 2023
October 26, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Improved diagnosis
Proportion of patients with "bad diagnosis" before scanning and "good diagnosis" after scanning (according to adjudication committee)
28 days after inclusion
Secondary Outcomes (3)
Discordant diagnosis
28 days after inclusion
Improvement in diagnostic certainty
28 days after inclusion
Scans performed
baseline (Day 0)
Study Arms (1)
CT scan intervention
EXPERIMENTALInterventions
A CT scan will be requested for every patient in addition to the chest X-ray
Eligibility Criteria
You may qualify if:
- Age greater than or equal to 65 years
- Acute dyspnea (\< 1 week)
- Prescription of a chest x-ray
- Oral free and informed consent of the patient after information and delivery of the information note
- Patient affiliated to a social security system
You may not qualify if:
- Inability to lie down
- Chest imaging done within the last 7 days
- Indication to perform a thoracic scan
- Patient under guardianship or curatorship
- Patient deprived of liberty, pregnant woman
- Participation in other interventional research
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Emergency department Hospital Pitié-Salpêtrière
Paris, 75013, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Yonathan FREUND, PU-PH
Assistance Publique - Hôpitaux de Paris
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 20, 2023
First Posted
October 27, 2023
Study Start
December 1, 2023
Primary Completion
October 1, 2024
Study Completion
November 1, 2024
Last Updated
October 27, 2023
Record last verified: 2023-10
Data Sharing
- IPD Sharing
- Will not share