Evaluation of the Impact of Lung Ultrasound on Mortality and Rehospitalization in Patients Admitted to the Emergency Department With Dyspnea

NCT05787665 | Completed

• 2 other identifiers: 69HCL23_00022023-A00177-38
• Study Type: observational
• Target: 385
• Locations: 1 country
• Sites: 1

Brief Summary

Dyspnea is a frequent reason for referral to emergency departments, leading to a 30-day mortality rate of up to 10% and a 3-month rehospitalization rate of over 30%. Multiple etiologies, as well as poor performance of clinical examination and chest radiography, lead to a diagnostic error rate of nearly 30% at the end of emergency department care. These diagnostic errors lead to rehospitalization and an excess mortality rate of more than 50% compared to patients with a correct initial diagnosis, which is explained in particular by the use of inappropriate therapies. Lung ultrasound is a rapid, non-irradiating, non-invasive, inexpensive, reproducible imaging test that can be used at the bedside. It has a better diagnostic performance than chest radiography, commonly performed in emergency departments.The immediate benefit of lung ultrasound for the most common diagnoses in emergency medicine has already been demonstrated. From an organizational point of view, a few studies have shown a benefit of lung ultrasound in reducing the time spent in emergency departments and the number of additional examinations necessary for the final diagnosis. However, there is no data in the literature on the longer term impact of its use in the emergency department. The primary objective is to evaluate the impact of performing lung ultrasound in terms of 3-month mortality and rehospitalization as part of the diagnostic process for patients admitted to the emergency department with dyspnea.

Conditions

Dyspnea

Keywords

Lung ultrasonography; emergency department; mortality; rehospitalization

Outcome Measures

Primary Outcomes (2)

• The primary objective is to evaluate the impact of performing lung ultrasound in terms of 3-month mortality as part of the diagnostic process for patients admitted to the emergency department with dyspnea.

  The primary endpoint is the rate of mortality at 3 months.

  at 3 months

• The primary objective is to evaluate the impact of performing lung ultrasound in terms of 3-month rehospitalization as part of the diagnostic process for patients admitted to the emergency department with dyspnea.

  the primary endpoint is the rate of rehospitalization at 3 months

  at 3 months

Study Arms (2)

With Lung Ultrasonography

Patient who meet inclusions criteria, and which lung ultrasonography were performed during their medical care in Emergency Department

Other: phone call at 3 months

Without Lung Ultrasonography

Patient who meet inclusions criteria, and which lung ultrasonography were not performed during their medical care in Emergency Department.

Other: phone call at 3 months

Interventions

phone call at 3 months OTHER

patients will be called at 3 months to know if they are alive and to know if they have been rehospitalized

With Lung Ultrasonography; Without Lung Ultrasonography

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This study will focus on adult patients consulting for dyspnea in the emergency department of the Edouard-Herriot Hospital (HCL).

You may qualify if:

• Age ≥ 18 years
• Admission to the emergency department with dyspnea defined by:
• The functional sign of dyspnea experienced by the patient; Or a clinical sign of respiratory distress.
• \- Non-opposition of the patient or patient's family if the patient isn't able

You may not qualify if:

• Trauma-induced dyspnea;
• Patient being on palliative care;
• Patient with criteria for initial resuscitation with admission to a critical care unit;
• Pregnant women, women in labour or nursing mothers;
• Persons deprived of liberty by judicial or administrative decision;
• Persons under psychiatric care;
• Persons admitted to a health or social institution for purposes other than research;
• Persons of full age subject to a legal protection measure (guardianship, curatorship);

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Hôpital Edouard-Herriot - Emergency Department

Lyon, 69003, France

Location

MeSH Terms

Conditions

Dyspnea; Emergencies

Condition Hierarchy (Ancestors)

Respiration Disorders; Respiratory Tract Diseases; Signs and Symptoms, Respiratory; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Disease Attributes; Pathologic Processes

Study Officials

• JULIA MORERE, MD

  Hospices Civils de Lyon

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 15, 2023
• First Posted: March 28, 2023
• Study Start: June 16, 2023
• Primary Completion: November 28, 2025
• Study Completion: November 28, 2025
• Last Updated: January 8, 2026

Record last verified: 2026-01

Locations

FR (1)