NCT05647655

Brief Summary

Evaluating the capability and efficiency of transthoracic ultrasound in attempting to identify the etiology of acute dyspnea.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
143

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2023

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 3, 2022

Completed
9 days until next milestone

First Posted

Study publicly available on registry

December 12, 2022

Completed
2 months until next milestone

Study Start

First participant enrolled

February 20, 2023

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2024

Completed
Last Updated

February 24, 2023

Status Verified

December 1, 2022

Enrollment Period

1 year

First QC Date

December 3, 2022

Last Update Submit

February 22, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Differentiate between different etiologies of acute dyspnea

    Analysis of ultrasound findings to differentiate between etiologies of acute dyspnea.

    Baseline

Secondary Outcomes (1)

  • Detect value of transthoracic ultrasound (TTU) in comparison to CT chest.

    Baseline

Interventions

Bedside thoracic ultrasound for patients complaining of acute dyspnea.

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients older than 18 years with acute dyspnea will be included

You may qualify if:

  • Clinical history of acute dyspnea

You may not qualify if:

  • Subcutaneous emphysema.
  • Patients with more than 24 h interval between HRCT and TTU.
  • Patients with poor-quality of TTU image.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Assiut University hospital

Asyut, 71515, Egypt

RECRUITING

Related Publications (5)

  • Gargani L, Fontana M, Sicari R, Picano E. [Differential diagnosis of dyspnea: the incremental value of lung ultrasound]. Recenti Prog Med. 2010 Feb;101(2):78-82. Italian.

    PMID: 20433006BACKGROUND
  • Baid H, Vempalli N, Kumar S, Arora P, Walia R, Chauhan U, Shukla K, Verma A, Chawang H, Agarwal D. Point of care ultrasound as initial diagnostic tool in acute dyspnea patients in the emergency department of a tertiary care center: diagnostic accuracy study. Int J Emerg Med. 2022 Jun 13;15(1):27. doi: 10.1186/s12245-022-00430-8.

    PMID: 35698060BACKGROUND
  • Vitturi N, Soattin M, Allemand E, Simoni F, Realdi G. Thoracic ultrasonography: A new method for the work-up of patients with dyspnea(). J Ultrasound. 2011 Sep;14(3):147-51. doi: 10.1016/j.jus.2011.06.009. Epub 2011 Jun 30.

    PMID: 23396858BACKGROUND
  • Li H, Li YD, Zhu WW, Sun LL, Ye XG, Kong LY, Cai QZ, Jiang W, Wang L, Lu XZ. High-Resolution Transthoracic Ultrasonography for Assessment of Pleural Lines in Patients With Dyspnea With CT Comparison: An Observational Study. J Ultrasound Med. 2017 Apr;36(4):707-716. doi: 10.7863/ultra.16.04030. Epub 2017 Jan 27.

    PMID: 28127786BACKGROUND
  • Lancellotti P, Price S, Edvardsen T, Cosyns B, Neskovic AN, Dulgheru R, Flachskampf FA, Hassager C, Pasquet A, Gargani L, Galderisi M, Cardim N, Haugaa KH, Ancion A, Zamorano JL, Donal E, Bueno H, Habib G. The use of echocardiography in acute cardiovascular care: recommendations of the European Association of Cardiovascular Imaging and the Acute Cardiovascular Care Association. Eur Heart J Cardiovasc Imaging. 2015 Feb;16(2):119-46. doi: 10.1093/ehjci/jeu210. Epub 2014 Nov 6.

    PMID: 25378470BACKGROUND

MeSH Terms

Conditions

Dyspnea

Interventions

Ultrasonography

Condition Hierarchy (Ancestors)

Respiration DisordersRespiratory Tract DiseasesSigns and Symptoms, RespiratorySigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Diagnostic ImagingDiagnostic Techniques and ProceduresDiagnosis

Study Officials

  • Ahmed A Elsayed, MBBCH

    Assiut University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ahmed A Elsayed, MBBCH

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

December 3, 2022

First Posted

December 12, 2022

Study Start

February 20, 2023

Primary Completion

March 1, 2024

Study Completion

April 1, 2024

Last Updated

February 24, 2023

Record last verified: 2022-12

Locations