Investigation of The Effects of Holistic Group Exercise Program on Muscle Thickness and Physical Performance in Older Adults With Sarcopenia

NCT05705934 | Unknown

• 1 other identifier: 2022-1268
• Study Type: interventional
• Target: 34
• Locations: 0 countries
• Sites: N/A

Brief Summary

A decrease in muscle mass and function can cause the development of many chronic diseases, including sarcopenia. It has been reported that the best intervention for sarcopenia is exercise. Despite this, the optimal type of exercise for sarcopenia has not yet been determined. Although the holistic approach is used in the literature in the elderly population, it is noticeable that it does not find much space for itself in this patient group. In this study, it was aimed to examine the effects of holistic approach-based exercise program on individuals with sarcopenia.

Conditions

Sarcopenia

Outcome Measures

Primary Outcomes (3)

• Muscle Mass

  Muscle ultrasound (US) is a feasible and practical tool to predict sarcopenia. It provides scope for the efficient assessment of muscle quality whilst providing insight into the pathophysiology of sarcopenia in addition to the diagnosis of low muscle mass. US has distinct advantages over other available modalities for muscle mass because the tool allows for separate measurements of individual muscle groups in addition to being safe and portable.

  Change from baseline at 12 weeks

• The Timed Up&Go Test

  It is a balance test used in the evaluation of functional mobility in the elderly. In the timed up and go (TUG) test, subjects are asked to rise from a standard armchair, walk to a marker 3 m away, turn, walk back, and sit down again. The elapsed time in this sequence is recorded in seconds. Patients wear their regular footwear and can use a walking aid, if needed.

  Change from baseline at 12 weeks

• Short Physical Performance Battery (SPPB)

  The short physical performance battery (SPPB) is a group of measures that combines the results of the gait speed, chair stand and balance tests. It has been used as a predictive tool for possible disability and can aid in the monitoring of function in older people. The scores range from 0 (worst performance) to 12 (best performance). A patient's score below 10 is the inclusion criterion for sarcopenia.

  Change from baseline at 12 weeks

Secondary Outcomes (7)

• SARC-F Questionnaire

  Change from baseline at 12 weeks

• Charlson Comorbidity Index

  Change from baseline at 12 weeks

• 30-Second Chair Stand Test

  Change from baseline at 12 weeks

• Hand Grip Strength

  Change from baseline at 12 weeks

• Berg Balance Test

  Change from baseline at 12 weeks

Study Arms (2)

Group 1

EXPERIMENTAL

Participants in this group will receive holistic-based group exercise program. All evaluations in this group will be done in the form of before and after. The exercise program will be applied for 12 weeks, 3 days a week.

Other: Exercise

Group 2

NO INTERVENTION

Participants in this group will continue their routine habits and nutrition programs. All assessments in this group will be done in the form of before and after.

Interventions

Exercise OTHER

Each session of the exercise program will last 50 minutes and will consist of 4 stages. At these stages, it is aimed to work the social, physical, spiritual and mental parameters of the holistic approach.

Group 1

Eligibility Criteria

• Age: 65 Years - 105 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Being over the age of 65
• Getting a diagnosis of sarcopenia
• To be able to walk at least 10 meters independently in public
• Getting a score of 4 and above from the clock drawing test
• Volunteer individuals

You may not qualify if:

• Having a neurological disease
• Having an uncontrollable cardiopulmonary disease
• Acute illness that will prevent him/her from understanding and performing the exercises to be performed status or the presence of significant cognitive impairment
• Providing continuity for less than 80% of the exercise program

Sponsors & Collaborators

• Ondokuz Mayıs University: lead
• Ankara Yildirim Beyazıt University: collaborator

MeSH Terms

Conditions

Sarcopenia

Interventions

Exercise

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer

Study Record Dates

• First Submitted: January 20, 2023
• First Posted: January 31, 2023
• Study Start: March 30, 2023
• Primary Completion: August 30, 2024
• Study Completion: November 30, 2024
• Last Updated: January 31, 2023

Record last verified: 2023-01