Effects of Dual-Task Training In Individuals With Alzheimer

NCT05765552 | Completed

• 1 other identifier: MOzkeskin874
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to investigate the effects of dual-task training on balance, fear of falling, cognitive functions, dual-task performance, depression and quality of life in individuals with Alzheimer.

Conditions

Alzheimer Disease

Keywords

Alzheimer; Fear of falling; Dual-task; Balance; Cognition

Outcome Measures

Primary Outcomes (5)

• Timed Up And Go(TUG)

  It is a frequently used test that evaluates functional mobility and dynamic balance. At the beginning of the test, individuals sit in a chair. A distance of 3 m is set in front of the patient. With the start command, the patient gets up from his seat and walks 3 m, turns around and walks back and sits. With the start command, the time until the moment of sitting on the chair is recorded in seconds.Shorter duration indicates better functional mobility.

  eight weeks

• 5 Times Sit To Stand Test(5XSST)

  5XSST evaluates lower extremity functional strength, transitional movements, balance and fall risk. The time it takes for the participant to sit and get up from a chair 5 times is recorded in seconds. Interpretations are made about balance and fall risk by comparing the norm times for age with the time the individual completes the test.

  eight weeks

• Cognitive Reserve Index Questionaire(CRIq)

  CRIq assesses an individual's cognitive reserve through compiling information about their entire adult life. If the participant has a suspected or confirmed cognitive weakness, the questionnaire must be answered by a family member or caregiver. The total score is obtained by recording the frequency of the individual's educational life, work and leisure activities in years. According to the score, the participant's cognitive reserve is interpreted as low, low - medium, medium, medium - high or high

  eight weeks

• Quality of Life in Alzheimer's Disease(QOL-AD)

  There are two versions of the scale: patient and family member/caregiver. In order to maximize construct validity, the scale is filled in independently by both patients and caregivers. It consists of questions asked about different aspects of life in order to determine the quality of life of the person. For each question, they are asked to choose the most appropriate one from the Poor, Fair, Good or Excellent answers.Higher scores indicate better quality of life.

  eight weeks

• Geriatric Depression Scale(GDS)

  The scale consists of 30 questions questioning how the participant felt in the past week. The person is asked to give the appropriate Yes(0) or No(1) answer to each question.Scores higher than 5 indicate depression.

  eight weeks

Secondary Outcomes (3)

• Dual-Task Questionnaire(DTQ)

  eight weeks

• Modified Falling Efficacy Scale(MFES)

  eight weeks

• Mini Mental Test(MMT)

  eight weeks

Study Arms (2)

Control Group

ACTIVE COMPARATOR

Participants in control group will receive an exercise program consisted of upper and lower range of motion exercises.The exercises will be started as 8-10 repetitions and 1 set and the number of sets will be increased according to the progression of the patient. Exercises will be applied for 8 weeks, 2 days a week, each session will last for 30 minutes.

Other: Control Group

Dual-Task Training Group

EXPERIMENTAL

Participants in the dual-task training group will receive exercises involving both motor and cognitive functions.Dual-task training sessions will begin with 10 minutes of stretching and proceed with 20 minutes of motor-cognitive dual-task exercises (counting backwards from 30 on double stance, naming the months and singing when standing on soft surfaces, finding words that starts with a given letter etc.) and sessions will end with 10 minutes of cooling.Exercises will be applied for 8 weeks 2 days a week each session will last for 30 minutes.

Other: Dual-Task Training

Interventions

Dual-Task Training OTHER

Motor-cognitive dual-task exercises will be applied for 2 days a week for 8 weeks.Sessions will last for 30 minutes.

Dual-Task Training Group

Control Group OTHER

Upper and lower extremity range of motion exercises will be applied for 8-10 repetitions for 1 set 2 times a week for 8 weeks.

Control Group

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• having been diagnosed with mild or moderate Alzheimer's disease
• able to walk with or without assistance
• having sufficient visual and auditory ability to perform the cognitive tests
• being fit to perform physical exercises
• being able to participate in proposed interventions and assessments

You may not qualify if:

• having a neurological disorder other than Alzheimer
• having any musculoskeletal problems that can affect balance
• having any contraindication to exercise
• functional limitation or sensory impairment that may affect performance
• major depression

Sponsors & Collaborators

• Ege University: lead

Study Sites (1)

Karsiyaka Municipality Day Living Center

Izmir, Karsıyaka, 35580, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Alzheimer Disease

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Dementia; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Neurocognitive Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Sevnaz ŞAHIN, PhD

  Ege University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asisstant Professor

Study Record Dates

• First Submitted: March 1, 2023
• First Posted: March 13, 2023
• Study Start: April 15, 2023
• Primary Completion: December 15, 2023
• Study Completion: April 15, 2024
• Last Updated: November 20, 2025

Record last verified: 2025-11

Locations

TU (1)