NCT05760547

Brief Summary

The Translational Initiative to Map Epigenetics in Aging (TIME-A) study aims to advance our understanding of the connections between epigenetics, lifestyle, demographics, and health and aging.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25,000

participants targeted

Target at P75+ for all trials

Timeline
84mo left

Started Mar 2023

Longer than P75 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress31%
Mar 2023Mar 2033

First Submitted

Initial submission to the registry

February 9, 2023

Completed
27 days until next milestone

First Posted

Study publicly available on registry

March 8, 2023

Completed
Same day until next milestone

Study Start

First participant enrolled

March 8, 2023

Completed
10.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2033

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2033

Last Updated

March 8, 2023

Status Verified

February 1, 2023

Enrollment Period

10.1 years

First QC Date

February 9, 2023

Last Update Submit

February 27, 2023

Conditions

Biological Aging

Outcome Measures

Primary Outcomes (3)

  • Effect of environmental and lifestyle factors on biological age

    Univariate and multivariate statistical methods will be used to identify which environmental and lifestyle factors (from TIME-A survey responses) influence biological age.

    At baseline and throughout study (approximately every 6 months up to 120 months)

  • Effect of general health on biological age

    Univariate and multivariate statistical methods will be used to identify which general health characteristics (from TIME-A survey responses) influence biological age.

    At baseline and throughout study (approximately every 6 months up to 120 months)

  • Effect of medical history on biological age

    Univariate and multivariate statistical methods will be used to identify the impact of medical history (from TIME-A survey responses) on biological age.

    At baseline and throughout study (approximately every 6 months up to 120 months)

Other Outcomes (1)

  • Develop epigenetic signatures that are predictive of health status

    At baseline and throughout study (approximately every 6 months up to 120 months)

Study Arms (1)

TIME-A

Group will complete periodic surveys

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Adults 18 or older

You may qualify if:

  • All adults aged 18 and above
  • Have registered at least one Index kit via the Elysium Health website
  • Able and willing to provide digital consent to the Research Consent Form, and the TIME-A Research Subject Consent Form

You may not qualify if:

  • Consent to participate not given

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Dayle Sampson, PhD

    Elysium Health

    PRINCIPAL INVESTIGATOR

  • Holly Holmes, PhD

    Elysium Health

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Ryan Dellinger, PhD

CONTACT

(888) 220 6436care@elysiumhealth.com

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 9, 2023

First Posted

March 8, 2023

Study Start

March 8, 2023

Primary Completion (Estimated)

March 31, 2033

Study Completion (Estimated)

March 31, 2033

Last Updated

March 8, 2023

Record last verified: 2023-02

Data Sharing

IPD Sharing
Will not share