"MecPain", a New Questionnaire to Assess Chronic Pain Mechanisms.

NCT05713604 | Unknown

• 1 other identifier: Grenoble University Hospital
• Study Type: observational
• Target: 240
• Locations: 1 country
• Sites: 2

Brief Summary

Validation of a new clinical questionnaire, called 'MecPain', including 12 questions, aimed at better defining the pathophysiological mechanisms of a chronic pain condition. This questionnaire includes 8 components/sub-components, reflecting various aspects of the 3 main mechanisms of chronic pain: nociceptive, neuropathic, nociplastic. A series of 240 patients with well-characterized chronic pain syndrome (for more than 6 months) of the nociceptive, neuropathic or nociplastic type will be recruited (80 patients per type of pain). The patients will be interviewed by a pain specialist to complete the 12 questions of the questionnaire during a routine visit in a Pain Center (CHU Grenobles Alpes, Grenoble, France or CHU Henri Mondor, Creteil, France). The scoring obtained with the 'MecPain' questionnaire will be compared to the presence of neuropathic pain assessed by two previously validated questionnaires, the 'DN4' and the 'PainDETECT' questionnaires. The expected outcome is a validation of the 'MecPain' questionnaire to provide a better understanding of the pathophysiological mechanisms relating to the presence of a chronic pain syndrome in a given patient.

Conditions

Chronic Pain

Keywords

Neuropathic pain; Nociplastic pain; Nociceptive pain; Chronic pain mechanisms

Outcome Measures

Primary Outcomes (1)

• The scores of the various components of the 'MecPain' questionnaire

  A score will be assigned based on the answers to each of the 12 questions of the 'MecPain' questionnaire

  Six months

Secondary Outcomes (1)

• The scores of the'DN4' and 'PainDETECT' questionnaires

  Six months

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with chronic pain for more than 6 months.

You may qualify if:

• Presence of a chronic pain syndrome (pain for more than 6 months);
• well-characterized pain syndrome of the nociceptive, neuropathic or nociplastic type

You may not qualify if:

• Opposition to the use of data obtained in the context of standard clinical follow-up.

Sponsors & Collaborators

• University Hospital, Grenoble: lead

Study Sites (2)

CHU de GRENOBLE ALPES

Grenoble, Alpes, 38043, France

RECRUITING

Henri Mondor

Paris, France

RECRUITING

MeSH Terms

Conditions

Chronic Pain; Neuralgia; Nociplastic Pain; Nociceptive Pain

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases

Central Study Contacts

Hasan HODAJ, MD - PhD

CONTACT

0476765213; hhodaj@chu-grenoble.fr

Jean-Pascal LEFAUCHEUR, MD - PhD

CONTACT

jean-pascal.lefaucheur@aphp.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 26, 2023
• First Posted: February 6, 2023
• Study Start: February 2, 2023
• Primary Completion: July 31, 2023
• Study Completion: December 1, 2023
• Last Updated: August 3, 2023

Record last verified: 2023-01

Data Sharing

• IPD Sharing: Will not share

Locations

FR (2)