NCT04880096

Brief Summary

Chronic pain affects approximately 20% of adults, 50% of the elderly population and over 1.5 billion people worldwide. Societal and economic issues are also crucial, as 60% of people with pain are less able or unable to work and 20% say they have lost their jobs because of pain. The overall cost of chronic pain is estimated at around 300 billion euros in the EU. Unfortunately, current treatments for chronic pain have limited effectiveness and important adverse effects. Pain clinics, which support the most complex and refractory cases of chronic pain, as well as general practitioners and patients expect improvements, both in terms of therapeutic efficacy and organization of care. In order to allow the characterization and a personalized follow-up of chronic pain patients, we have created e-DOL, a smartphone application for patients and a web platform for healthcare professionals in pain clinics. The purpose of this study is to create an e-cohort for the research, and characterization and follow-up of chronic pain patients.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5,000

participants targeted

Target at P75+ for all trials

Timeline
3mo left

Started Sep 2021

Longer than P75 for all trials

Geographic Reach
1 country

22 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress94%
Sep 2021Sep 2026

First Submitted

Initial submission to the registry

May 5, 2021

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 10, 2021

Completed
4 months until next milestone

Study Start

First participant enrolled

September 14, 2021

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2026

Last Updated

April 1, 2026

Status Verified

March 1, 2026

Enrollment Period

5 years

First QC Date

May 5, 2021

Last Update Submit

March 31, 2026

Conditions

Chronic Pain

Keywords

Chronic Paine-Health

Outcome Measures

Primary Outcomes (1)

  • multidimensional characterisation of chronic pain patients

    Multimodal exploratory analysis of the determinants and repercussions of chronic pain, and their evolution in a real-life context, taking into account all environmental events likely to influence chronic pain (treatments, history, co-morbidities, etc.).

    5 years

Secondary Outcomes (2)

  • Multivariate descriptive analyses

    5 years

  • Longitudinal analyses

    5 years

Study Arms (1)

chronic pain patients

All adult patients followed-up in participating pain clinics

Other: eDOL

Interventions

eDOLOTHER

e-health tool (mobile app for patients and web platform for caregivers in pain clinics)

chronic pain patients

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patiant with chronic pain

You may qualify if:

  • All patients with chronic pain
  • patients equipped and regular users of a smartphone
  • Non-opposition to participation in the study

You may not qualify if:

  • Patient unable to understand or answer questionnaires

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (22)

CHU de Clermont-Ferrand - Service de Neurologie

Clermont-Ferrand, AURA, 63000, France

RECRUITING

Clermont-Ferrand University Hospital

Clermont-Ferrand, AURA, 63000, France

RECRUITING

APHP Ambroise Paré

Boulogne-Billancourt, IDF, 92100, France

RECRUITING

APHP Saint Antoine

Paris, IDF, 75012, France

RECRUITING

APHP Cochin

Paris, IDF, 75014, France

RECRUITING

Groupe Hospitalier Paris Saint Joseph

Paris, IDf, 75014, France

RECRUITING

CHU Amiens

Amiens, 80054, France

RECRUITING

CH Bayeux

Bayeux, 14400, France

NOT YET RECRUITING

CHU bordeaux

Bordeaux, 33000, France

NOT YET RECRUITING

Hospices civils Lyon

Bron, 69500, France

RECRUITING

CHU Grenoble

Grenoble, 38700, France

RECRUITING

CHU Limoges

Limoges, 87000, France

RECRUITING

Ch Lons Le Saunier

Lons-le-Saunier, 39000, France

RECRUITING

CHU Montepllier

Montpellier, France

NOT YET RECRUITING

CHU Nantes

Nantes, 44093, France

RECRUITING

CHU Nîmes

Nîmes, 30029, France

RECRUITING

CHU Rennes

Rennes, 35000, France

RECRUITING

Chu Rouen

Rouen, 76000, France

RECRUITING

CHU Saint Etienne

Saint-Etienne, 42270, France

RECRUITING

Hôpital Civil de Strasbourg

Strasbourg, France

RECRUITING

Chu Toulouse

Toulouse, 31300, France

RECRUITING

CH Voiron

Voiron, 38500, France

RECRUITING

Related Publications (1)

  • Delage N, Cantagrel N, Soriot-Thomas S, Frost M, Deleens R, Ginies P, Eschalier A, Corteval A, Laveyssiere A, Phalip J, Bertin C, Pereira B, Chenaf C, Doreau B, Authier N; ePAIN; Kerckhove N. Mobile Health App and Web Platform (eDOL) for Medical Follow-Up of Patients With Chronic Pain: Cohort Study Involving the French eDOL National Cohort After 1 Year. JMIR Mhealth Uhealth. 2024 Jun 12;12:e54579. doi: 10.2196/54579.

    PMID: 38865173DERIVED

MeSH Terms

Conditions

Chronic Pain

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Lise Laclautre

CONTACT

04 73 75 11 95promo_interne_drci@chu-clermontferrand.fr

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 5, 2021

First Posted

May 10, 2021

Study Start

September 14, 2021

Primary Completion (Estimated)

September 1, 2026

Study Completion (Estimated)

September 1, 2026

Last Updated

April 1, 2026

Record last verified: 2026-03

Locations

FR(22)