Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

NCT05712200 | Recruiting Phase 3 DMC FDA Drug

• 3 other identifiers: ANT-0102023-503224-66-00CMAA868A2302
• Study Type: interventional
• Target: 1,900
• Locations: 32 countries
• Sites: 719

Brief Summary

A study to evaluate the effect of abelacimab relative to placebo on the rate of ischemic stroke or systemic embolism (SE) in patients with Atrial Fibrillation (AF) who have been deemed by their responsible physicians or by their own decision to be unsuitable for oral anticoagulation therapy.

Conditions

Atrial Fibrillation (AF)

Keywords

abelacimab; randomized; placebo-controlled; double-blind; endpoint evaluation; atrial fibrillation

Outcome Measures

Primary Outcomes (2)

• Efficacy: Time to first event of ischemic stroke or systemic embolism (SE)

  Up to 30 months

• Safety: Time to first occurrence of Bleeding Academic Research Consortium (BARC) type 3c/5 bleeding

  Up to 30 months

Secondary Outcomes (5)

• Efficacy: Time to first event of ischemic stroke, systemic embolism (SE), myocardial infarctions (MI), venous thromboembolism (VTE), or acute limb ischemia

  Up to 30 months

• Efficacy: Time to first event of ischemic stroke, systemic embolism (SE), or Bleeding Academic Research Consortium (BARC) type 3c/5 bleeding event

  Up to 30 months

• Efficacy: Cardiovascular (CV) mortality

  Up to 30 months

• Efficacy: All-cause mortality

  Up to 30 months

• Time to first event of ischemic stroke, systemic embolism (SE), myocardial infarctions (MI), venous thromboembolism (VTE), acute limb ischemia, or International Society on Thrombosis and Haemostasis (ISTH) major bleeding

  Up to 30 months

Study Arms (2)

Abelacimab (MAA868)

EXPERIMENTAL

Patients will be randomized in a 1:1 ratio to receive abelacimab 150 mg subcutaneous (SC) or matching placebo once monthly.

Biological: Abelacimab

Placebo

PLACEBO COMPARATOR

Patients will be randomized in a 1:1 ratio to receive abelacimab 150 mg subcutaneous (SC) or matching placebo once monthly.

Drug: Placebo

Interventions

Abelacimab BIOLOGICAL

Abelacimab provided as liquid in vial (150 mg/mL)

Also known as: MAA868

Abelacimab (MAA868)

Placebo DRUG

Dosage Formulation: Liquid (in vial) Dose Strength: Placebo to Abelacimab

Placebo

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)

You may qualify if:

• Patient is able to understand and has provided written informed consent to participate in the trial
• Diagnosed Atrial Fibrillation (AF) or atrial flutter (documented on an electrocardiogram (ECG) or monitor recording)
• Age 65-74 and a CHA2DS2VASc ≥4 OR age ≥75 and a CHA2DS2VASc ≥3
• Patient is judged by the responsible physician to be unsuitable for oral anticoagulation because the risks outweigh the benefits or the patient is unwilling to take oral anticoagulation AND this determination was made prior to and independent of the study
• At least 1 bleeding risk factor such as severe renal insufficiency, planned daily use of antiplatelet medication for the duration of the trial, history of bleeding from a critical area, or other conditions associated with increased risk of bleeding such as chronic nonsteroidal anti-inflammatory drug (NSAID) use, frailty or multiple falls
• Patient is judged by the responsible physician to be unsuitable for left atrial appendage (LAA) closure or occlusion device, an approved device is not available, or the patient is unwilling to undergo the procedure AND this determination was made prior to and independent of the study

You may not qualify if:

• AF due to an ongoing acute reversible cause (e.g., cardiac surgery, pulmonary embolism (PE), untreated hyperthyroidism, alcohol use)
• Patients who within 60 days prior to randomization (1) received a vitamin K antagonists (VKA) (e.g., warfarin, phenprocoumon, acenocoumarol) or a direct oral anticoagulant (DOAC) such as, dabigatran, rivaroxaban, apixaban, or edoxaban or (2) were newly diagnosed with AF
• Patients with an intracranial or intraocular bleed within the 3 months prior to screening or any history of spontaneous intracerebral hemorrhage at any time in the absence of antithrombotic treatment
• Any stroke within 14 days before randomization or transient ischemic attack (TIA) within 3 days before randomization
• Mechanical heart valve or valve disease that is expected to require mechanical valve replacement intervention (surgical or invasive) during the course of the study
• Patients on dialysis at screening or who are planned to start dialysis within 6 months

Sponsors & Collaborators

• Novartis Pharmaceuticals: collaborator
• Anthos Therapeutics, Inc.: lead

Study Sites (734)

Anthos Investigative Site 1040

Birmingham, Alabama, 35205, United States

RECRUITING

Anthos Investigational site 9939

Birmingham, Alabama, 35233, United States

RECRUITING

Anthos Investigative Site 9947

Birmingham, Alabama, 35243, United States

NOT YET RECRUITING

Anthos Investigative Site 1041

Mobile, Alabama, 36608, United States

RECRUITING

Anthos Investigative Site 1089

Gilbert, Arizona, 85296, United States

WITHDRAWN

Anthos Investigative Site 1099

Peoria, Arizona, 85381, United States

RECRUITING

Anthos Investigative Site 9906

Phoenix, Arizona, 85018, United States

RECRUITING

Anthos Investigative Site 9927

Yuma, Arizona, 85365, United States

RECRUITING

Anthos Investigative Site 9929

Huntington Beach, California, 92648, United States

RECRUITING

Anthos Investigative Site 9959

Imperial, California, 92251, United States

RECRUITING

Anthos Investigative Site 9921

Lancaster, California, 93534, United States

RECRUITING

Anthos Investigative Site 1078

Loma Linda, California, 92357, United States

RECRUITING

Anthos Investigative Site 1077

Los Angeles, California, 90022, United States

RECRUITING

Anthos Investigative Site 1015

Northridge, California, 91325, United States

WITHDRAWN

Anthos Investigative Site 1070

Redding, California, 96001, United States

ACTIVE NOT RECRUITING

Anthos Investigative Site 1071

San Dimas, California, 91773, United States

RECRUITING

Anthos Investigative Site 1076

Santa Ana, California, 92704, United States

WITHDRAWN

Anthos Investigative Site 9938

Santa Rosa, California, 95405, United States

RECRUITING

Anthos Investigative Site 9908

South Gate, California, 90280, United States

RECRUITING

Anthos Investigative Site 9907

Vista, California, 92081, United States

RECRUITING

Anthos Investigative Site 1095

Aurora, Colorado, 80045, United States

RECRUITING

Anthos Investigative Site 1049

Denver, Colorado, 80218, United States

WITHDRAWN

Anthos Investigative Site 9922

Golden, Colorado, 80228, United States

RECRUITING

Anthos Investigative Site 1012

Stamford, Connecticut, 06905, United States

RECRUITING

Anthos Investigative Site 9934

Altamonte Springs, Florida, 32714, United States

RECRUITING

Anthos Investigative Site 1013

Boca Raton, Florida, 33486, United States

RECRUITING

Anthos Investigational site 9810

Bradenton, Florida, 34209, United States

RECRUITING

Anthos Investigative Site 1025

Clearwater, Florida, 33756, United States

RECRUITING

Anthos Investigative Site 1022

Clearwater, Florida, 33777, United States

RECRUITING

Anthos Investigative Site 1019

Daytona Beach, Florida, 32114, United States

RECRUITING

Anthos Investigative Site 9936

Hialeah, Florida, 33012, United States

RECRUITING

Anthos Investigative Site 9804

Hollywood, Florida, 33020, United States

RECRUITING

Anthos Investigative Site 1083

Hollywood, Florida, 33024, United States

RECRUITING

Anthos Investigative Site 1008

Jacksonville, Florida, 32216, United States

WITHDRAWN

Anthos Investigative Site 9904

Lake Mary, Florida, 32746, United States

RECRUITING

Anthos Investigative Site 1093

Lutz, Florida, 33558, United States

RECRUITING

Anthos Investigative Site 9933

Miami, Florida, 33145, United States

RECRUITING

Anthos Investigative Site 1072

Miami Lakes, Florida, 33016, United States

WITHDRAWN

Anthos Investigative Site 9944

Ocala, Florida, 34471, United States

RECRUITING

Anthos Investigative Site 9940

Ocala, Florida, 34474, United States

RECRUITING

Anthos Investigative Site 1067

Ormond Beach, Florida, 32117, United States

WITHDRAWN

Anthos Investigational site 9802

Port Orange, Florida, 32117, United States

ACTIVE NOT RECRUITING

Anthos Investigative Site 1026

Safety Harbor, Florida, 34695, United States

RECRUITING

Anthos Investigative Site 1002

Saint Augustine, Florida, 32086, United States

RECRUITING

Anthos Investigative Site 1004

Saint Augustine, Florida, 32086, United States

RECRUITING

Anthos Investigative Site 1044

Tamarac, Florida, 33321, United States

RECRUITING

Anthos Investigative Site 1088

Tamarac, Florida, 33321, United States

RECRUITING

Anthos Investigative Site 1046

Tampa, Florida, 33625, United States

WITHDRAWN

Anthos Investigative Site 9911

The Villages, Florida, 32162, United States

RECRUITING

Anthos Investigative Site 1052

Lithonia, Georgia, 30058, United States

WITHDRAWN

Anthos Investigative Site 1033

Macon, Georgia, 31201, United States

RECRUITING

Anthos Investigative Site 1042

Norcross, Georgia, 30092, United States

WITHDRAWN

Anthos Investigative Site 1003

Suwanee, Georgia, 30024, United States

RECRUITING

Anthos Investigative Site 9953

Tucker, Georgia, 30084, United States

RECRUITING

Anthos Investigative Site 1030

Park Ridge, Illinois, 60068, United States

RECRUITING

Anthos Investigative Site 9932

Rockford, Illinois, 61107, United States

RECRUITING

Anthos Investigative Site 9925

Winfield, Illinois, 60190, United States

RECRUITING

Anthos Investigative Site 9915

Evansville, Indiana, 47714, United States

RECRUITING

Anthos Investigative Site 1098

Merrillville, Indiana, 46410, United States

RECRUITING

Anthos Investigative Site 9956

West Des Moines, Iowa, 50266, United States

RECRUITING

Anthos Investigative Site 9958

Hutchinson, Kansas, 67502, United States

RECRUITING

Anthos Investigative Site 1016

Wichita, Kansas, 67207, United States

RECRUITING

Anthos Investigative Site 1006

Alexandria, Louisiana, 71301, United States

WITHDRAWN

Anthos Investigative Site 1043

Shreveport, Louisiana, 71103, United States

RECRUITING

Anthos Investigational site 9803

West Monroe, Louisiana, 71291, United States

RECRUITING

Anthos Investigative Site 1054

Bangor, Maine, 04401, United States

RECRUITING

Anthos Investigative Site 1039

Baltimore, Maryland, 21218, United States

RECRUITING

Anthos Investigative Site 9957

Baltimore, Maryland, 21229, United States

RECRUITING

Anthos Investigative Site 1023

Lanham, Maryland, 20746, United States

RECRUITING

Anthos Investigational site 9962

Rockville, Maryland, 20850, United States

RECRUITING

Anthos Investigative Site 1028

Rockville, Maryland, 20850, United States

WITHDRAWN

Anthos Investigative Site 1082

Boston, Massachusetts, 02124, United States

WITHDRAWN

Anthos Investigative Site 9918

Boston, Massachusetts, 02215, United States

RECRUITING

Anthos Investigative Site 1021

Lansing, Michigan, 48912, United States

RECRUITING

Anthos Investigative Site 9946

Petoskey, Michigan, 49770, United States

RECRUITING

Anthos Investigative Site 1059

Southgate, Michigan, 48195, United States

RECRUITING

Anthos Investigative Site 1017

Tupelo, Mississippi, 38801, United States

WITHDRAWN

Anthos Investigative Site 1080

Kansa City, Missouri, 64151, United States

RECRUITING

Anthos Investigative Site 9948

Kansas City, Missouri, 64114, United States

RECRUITING

Anthos Investigative Site 1066

Lincoln, Nebraska, 68506, United States

RECRUITING

Anthos Investigative Site 1036

Las Vegas, Nevada, 89119, United States

WITHDRAWN

Anthos Investigative Site 9914

Las Vegas, Nevada, 89123, United States

RECRUITING

Anthos Investigative Site 1094

Englewood, New Jersey, 07631, United States

RECRUITING

Anthos Investigative Site 9931

Albany, New York, 12211, United States

RECRUITING

Anthos Investigative Site 9905

Brooklyn, New York, 11217, United States

RECRUITING

Anthos Investigative Site 1014

Middletown, New York, 10941, United States

WITHDRAWN

Anthos Investigative Site 1037

Rosedale, New York, 11422, United States

RECRUITING

Anthos Investigative Site 9935

Stony Brook, New York, 11794, United States

RECRUITING

Anthos Investigative Site 9920

Valhalla, New York, 10595, United States

RECRUITING

Anthos Investigative Site 9924

Westfield, New York, 14787, United States

RECRUITING

Anthos Investigative Site 1065

Cary, North Carolina, 27518, United States

RECRUITING

Anthos Investigative Site 1005

Charlotte, North Carolina, 28207, United States

RECRUITING

Anthos Investigative Site 9912

Durham, North Carolina, 27709, United States

RECRUITING

Anthos Investigative Site 1048

Fayetteville, North Carolina, 28314, United States

WITHDRAWN

Anthos Investigational site 9809

Greensboro, North Carolina, 27405, United States

ACTIVE NOT RECRUITING

Anthos Investigative Site 1035

Henderson, North Carolina, 28792, United States

WITHDRAWN

Anthos Investigative Site 1001

Lenoir, North Carolina, 28638, United States

WITHDRAWN

Anthos Investigative Site 9950

Pinehurst, North Carolina, 28374, United States

RECRUITING

Anthos Investigative Site 9951

Statesville, North Carolina, 28677, United States

RECRUITING

Anthos Investigative Site 9952

Wilmington, North Carolina, 28401, United States

RECRUITING

Anthos Investigative Site 9902

Beavercreek, Ohio, 45431, United States

RECRUITING

Anthos Investigative Site 9945

Dayton, Ohio, 45429, United States

RECRUITING

Anthos Investigative Site 9917

Oklahoma City, Oklahoma, 73104, United States

RECRUITING

Anthos Investigative Site 1075

Portland, Oregon, 97239, United States

RECRUITING

Anthos Investigative Site 1074

Bristol, Pennsylvania, 19007, United States

WITHDRAWN

Anthos Investigative Site 1087

Horsham, Pennsylvania, 19044, United States

RECRUITING

Anthos Investigative Site 1032

Rock Hill, South Carolina, 29732, United States

WITHDRAWN

Anthos Investigational site 9954

Chattanooga, Tennessee, 37403, United States

RECRUITING

Anthos Investigative Site 1050

Elizabethton, Tennessee, 37643, United States

WITHDRAWN

Anthos Investigative Site 1057

Germantown, Tennessee, 38138, United States

WITHDRAWN

Anthos Investigative Site 9941

Jefferson City, Tennessee, 37760, United States

RECRUITING

Anthos Investigative Site 1056

Memphis, Tennessee, 38128, United States

RECRUITING

Anthos Investigative Site 9928

Allen, Texas, 75013, United States

RECRUITING

Anthos Investigative Site 9913

Beaumont, Texas, 77702, United States

RECRUITING

Anthos Investigational site 9967

Bryan, Texas, 77802, United States

RECRUITING

Anthos Investigative Site 9943

Dallas, Texas, 75243, United States

RECRUITING

Anthos Investigative Site 9942

Dallas, Texas, 75254, United States

RECRUITING

Anthos Investigative Site 1091

El Paso, Texas, 79905, United States

RECRUITING

Anthos Investigative Site 9930

Greenville, Texas, 75401, United States

RECRUITING

Anthos Investigative Site 1069

Houston, Texas, 77002, United States

WITHDRAWN

Anthos Investigative Site 1068

Houston, Texas, 77025, United States

RECRUITING

Anthos Investigative Site 1097

Houston, Texas, 77055, United States

RECRUITING

Anthos Investigative Site 9903

Houston, Texas, 77070, United States

RECRUITING

Anthos Investigative Site 1053

Houston, Texas, 77074, United States

WITHDRAWN

Anthos Investigative Site 1064

Houston, Texas, 77084, United States

RECRUITING

Anthos Investigative Site 9901

Laredo, Texas, 78041, United States

WITHDRAWN

Anthos Investigative Site 1063

McAllen, Texas, 78503, United States

RECRUITING

Anthos Investigative Site 1096

McKinney, Texas, 75069, United States

RECRUITING

Anthos Investigative Site 1079

McKinney, Texas, 75071, United States

RECRUITING

Anthos Investigative Site 1024

Odessa, Texas, 79761, United States

RECRUITING

Anthos Investigative Site 1085

Port Arthur, Texas, 77642, United States

RECRUITING

Anthos Investigative Site 9923

Sherman, Texas, 75090, United States

RECRUITING

Anthos Investigative Site 1090

Sugar Land, Texas, 77479, United States

RECRUITING

Anthos Investigative Site 1011

Tomball, Texas, 77375, United States

WITHDRAWN

Anthos Investigative Site 9916

Tyler, Texas, 75701, United States

RECRUITING

Anthos Investigative Site 9910

Victoria, Texas, 77901, United States

RECRUITING

Anthos Investigative Site 1060

Waco, Texas, 76712, United States

RECRUITING

Anthos Investigative Site 9909

Webster, Texas, 77598, United States

RECRUITING

Anthos Investigative Site 1092

Wylie, Texas, 75098, United States

RECRUITING

Anthos Investigative Site 1084

American Fork, Utah, 84003, United States

WITHDRAWN

Anthos Investigative Site 1031

Bountiful, Utah, 84010, United States

WITHDRAWN

Anthos Investigative Site 1029

Holladay, Utah, 84117, United States

WITHDRAWN

Anthos Investigative Site 1038

Pleasant View, Utah, 84404, United States

WITHDRAWN

Anthos Investigative Site 1034

Roy, Utah, 84067, United States

WITHDRAWN

Anthos Investigative Site 1018

Falls Church, Virginia, 22042, United States

RECRUITING

Anthos Investigative Site 1010

Manassas, Virginia, 20109, United States

WITHDRAWN

Anthos Investigative Site 1009

Roanoke, Virginia, 24014, United States

RECRUITING

Anthos Investigative Site 9949

Vienna, Virginia, 22182, United States

RECRUITING

Anthos Investigative Site 9926

Redmond, Washington, 98052, United States

RECRUITING

Anthos Investigative Site 1073

Tacoma, Washington, 98405, United States

RECRUITING

Anthos Investigational site 1443

Buenos Aires, Buenos Aires F.D., C1187AAN, Argentina

RECRUITING

Anthos Investigational site 1463

Buenos Aires, Buenos Aires F.D., C1426EOB, Argentina

RECRUITING

Anthos Investigational site 1444

Córdoba, Córdoba Province, X5000AAW, Argentina

ACTIVE NOT RECRUITING

Anthos Investigational site 1439

Villa María, Córdoba Province, X5900JKA, Argentina

RECRUITING

Anthos Investigative Site 1411

Buenos Aires, 1425, Argentina

RECRUITING

Anthos Investigative Site 1430

Buenos Aires, 1431, Argentina

RECRUITING

Anthos Investigative Site 1409

Ciudad Autónoma Buenos Aires, 1061, Argentina

RECRUITING

Anthos Investigative Site 1410

Ciudad Autónoma de Buenos Aire, 1027, Argentina

RECRUITING

Anthos Investigative Site 1423

Ciudad Autónoma de Buenos Aire, 1428, Argentina

RECRUITING

Anthos Investigative Site 1429

Coronel Suárez, 7540, Argentina

RECRUITING

Anthos Investigative Site 1420

Corrientes, 5700, Argentina

RECRUITING

Anthos Investigative Site 1407

Córdoba, 5000, Argentina

RECRUITING

Anthos Investigative Site 1414

Córdoba, 5000, Argentina

RECRUITING

Anthos Investigative Site 1418

Córdoba, 5000, Argentina

RECRUITING

Anthos Investigative Site 1424

Córdoba, 5000, Argentina

RECRUITING

Anthos Investigative Site 1427

Córdoba, 5000, Argentina

RECRUITING

Anthos Investigative Site 1434

Córdoba, 5000, Argentina

RECRUITING

Anthos Investigative Site 1419

Córdoba, X5000, Argentina

RECRUITING

Anthos Investigative Site 1431

Córdoba, X5002AOQ, Argentina

RECRUITING

Anthos Investigative Site 1402

La Plata, 1900, Argentina

RECRUITING

Anthos Investigative Site 1417

Quilmes, 1878, Argentina

RECRUITING

Anthos Investigative Site 1415

Ramos Mejía, 1704, Argentina

RECRUITING

Anthos Investigative Site 1403

Salta, 4400, Argentina

RECRUITING

Anthos Investigative Site 1425

San Luis, 3400, Argentina

RECRUITING

Anthos Investigative Site 1426

San Martín, 1650, Argentina

RECRUITING

Anthos Investigative Site 1404

San Miguel de Tucumán, 4000, Argentina

RECRUITING

Anthos Investigative Site 1435

San Miguel de Tucumán, 4000, Argentina

RECRUITING

Anthos Investigative Site 1436

San Nicolás, 2900, Argentina

RECRUITING

Anthos Investigative Site 1518

Aracaju, 49055, Brazil

RECRUITING

Anthos Investigative Site 1527

Belo Horizonte, 30110-021, Brazil

RECRUITING

Anthos Investigative Site 1528

Belo Horizonte, 30110, Brazil

RECRUITING

Anthos Investigative Site 1516

Belo Horizonte, 30150-242, Brazil

RECRUITING

Anthos Investigative Site 1507

Belo Horizonte, 30220, Brazil

RECRUITING

Anthos Investigative Site 1513

Blumenau, 89010, Brazil

RECRUITING

Anthos Investigative Site 1505

Blumenau, 89020-430, Brazil

RECRUITING

Anthos Investigative Site 1535

Brasília, 70200-730, Brazil

RECRUITING

Anthos Investigative Site 1501

Campina Grande do Sul, 83430, Brazil

RECRUITING

Anthos Investigative Site 1503

Campinas, 13010, Brazil

WITHDRAWN

Anthos Investigative Site 1522

Campinas, 13060, Brazil

RECRUITING

Anthos Investigative Site 1520

Campo Grande, 79080-190, Brazil

RECRUITING

Anthos Investigative Site 1532

Canoas, 92425, Brazil

RECRUITING

Anthos Investigative Site 1526

Caxias do Sul, 95070, Brazil

RECRUITING

Anthos Investigative Site 1542

Colatina, 29707, Brazil

RECRUITING

Anthos Investigative Site 1540

Curitiba, 80045-395, Brazil

RECRUITING

Anthos Investigative Site 1509

Curitiba, 80730, Brazil

RECRUITING

Anthos Investigative Site 1525

Goiânia, 74605, Brazil

RECRUITING

Anthos Investigative Site 1502

Marília, 17515-000, Brazil

RECRUITING

Anthos Investigative Site 1533

Passo Fundo, 99010, Brazil

RECRUITING

Anthos Investigative Site 1517

Porto Alegre, 90020-090, Brazil

RECRUITING

Anthos Investigative Site 1519

Porto Alegre, 90035-903, Brazil

RECRUITING

Anthos Investigative Site 1544

Porto Alegre, 90160-093, Brazil

RECRUITING

Anthos Investigative Site 1506

Porto Alegre, 90560, Brazil

WITHDRAWN

Anthos Investigative Site 1530

Porto Alegre, 90610-000, Brazil

RECRUITING

Anthos Investigative Site 1512

Porto Alegre, 90620-001, Brazil

RECRUITING

Anthos Investigative Site 1524

Porto Alegre, 90840-440, Brazil

RECRUITING

Anthos Investigative Site 1508

Porto Alegre, 91350, Brazil

RECRUITING

Anthos Investigative Site 1531

Recife, 52051, Brazil

RECRUITING

Anthos Investigative Site 1515

Ribeirão Preto, 14026, Brazil

WITHDRAWN

Anthos Investigative Site 1536

Ribeirão Preto, 14051-140, Brazil

RECRUITING

Anthos Investigative Site 1537

Rio de Janeiro, 20241-180, Brazil

RECRUITING

Anthos Investigative Site 1510

Salvador, 40050, Brazil

RECRUITING

Anthos Investigative Site 1521

Salvador, 41810, Brazil

WITHDRAWN

Anthos Investigative Site 1534

São Paulo, 01232, Brazil

RECRUITING

Anthos Investigative Site 1511

São Paulo, 01323-001, Brazil

RECRUITING

Anthos Investigative Site 1538

São Paulo, 04012, Brazil

RECRUITING

Anthos Investigative Site 1539

São Paulo, 04024-002, Brazil

RECRUITING

Anthos Investigative Site 1529

São Paulo, 05403, Brazil

RECRUITING

Anthos Investigative Site 1543

São Paulo, 08270-070, Brazil

RECRUITING

Anthos Investigative Site 1514

Tatuí, 18270-170, Brazil

RECRUITING

Anthos Investigative Site 1541

Teresina, 64001-450, Brazil

RECRUITING

Anthos Investigative Site 1504

Votuporanga, 15500, Brazil

RECRUITING

Anthos Investigative Site 6014

Blagoevgrad, 2700, Bulgaria

RECRUITING

Anthos Investigative Site 6026

Burgas, 8000, Bulgaria

RECRUITING

Anthos Investigative Site 6019

Gabrovo, 5300, Bulgaria

RECRUITING

Anthos Investigative Site 6032

Haskovo, 6300, Bulgaria

RECRUITING

Anthos Investigative Site 6018

Haskovo, 6304, Bulgaria

RECRUITING

Anthos Investigative Site 6013

Panagyurishte, 4500, Bulgaria

RECRUITING

Anthos Investigative Site 6025

Pazardzhik, 4400, Bulgaria

RECRUITING

Anthos Investigative Site 6006

Pleven, 5804, Bulgaria

RECRUITING

Anthos Investigative Site 6003

Pleven, 5808, Bulgaria

RECRUITING

Anthos Investigative Site 6007

Plovdiv, 4000, Bulgaria

RECRUITING

Anthos Investigative Site 6008

Plovdiv, 4000, Bulgaria

RECRUITING

Anthos Investigative Site 6009

Plovdiv, 4000, Bulgaria

RECRUITING

Anthos Investigative Site 6004

Plovdiv, 4003, Bulgaria

RECRUITING

Anthos Investigative Site 6021

Plovdiv, 4003, Bulgaria

RECRUITING

Anthos Investigative Site 6031

Rousse, 7013, Bulgaria

RECRUITING

Anthos Investigative Site 6027

Sliven, 8800, Bulgaria

RECRUITING

Anthos Investigative Site 6034

Sliven, 8800, Bulgaria

RECRUITING

Anthos Investigative Site 6022

Smolyan, 4700, Bulgaria

RECRUITING

Anthos Investigative Site 6030

Sofia, 1142, Bulgaria

RECRUITING

Anthos Investigative Site 6028

Sofia, 1202, Bulgaria

RECRUITING

Anthos Investigative Site 6029

Sofia, 1233, Bulgaria

RECRUITING

Anthos Investigative Site 6024

Sofia, 1404, Bulgaria

RECRUITING

Anthos Investigative Site 6023

Sofia, 1407, Bulgaria

RECRUITING

Anthos Investigative Site 6010

Sofia, 1431, Bulgaria

RECRUITING

Anthos Investigative Site 6015

Sofia, 1431, Bulgaria

RECRUITING

Anthos Investigative Site 6020

Sofia, 1527, Bulgaria

RECRUITING

Anthos Investigative Site 6001

Sofia, 1606, Bulgaria

RECRUITING

Anthos Investigative Site 6017

Sofia, 1606, Bulgaria

RECRUITING

Anthos Investigative Site 6012

Sofia, 1618, Bulgaria

WITHDRAWN

Anthos Investigative Site 6002

Sofia, 1709, Bulgaria

RECRUITING

Anthos Investigative Site 6011

Stara Zagora, 6000, Bulgaria

WITHDRAWN

Anthos Investigative Site 2012

Mira Road, Nova Scotia, B1M DA1, Canada

RECRUITING

Anthos Investigative Site 2003

Cambridge, Ontario, N1R 7R1, Canada

RECRUITING

Anthos Investigative Site 2007

Chicoutimi, Quebec, G7H 5H6, Canada

RECRUITING

Anthos Investigative Site 2010

Sherbrooke, Quebec, J1H 5N4, Canada

RECRUITING

Anthos Investigative Site 2016

Abbotsford British Columbia, V2S 0C2, Canada

RECRUITING

Anthos Investigative Site 2019

Brampton, L6R 3J7, Canada

RECRUITING

Anthos Investigative Site 2015

Edmonton, T6G 2G3, Canada

RECRUITING

Anthos Investigative Site 2018

Greenfield Park, J4V 2H1, Canada

RECRUITING

Anthos Investigative Site 2005

Halifax, B3H 3A7, Canada

RECRUITING

Anthos Investigative Site 2025

Hamilton, L8L 2X2, Canada

RECRUITING

Anthos Investigative Site 2026

Hamilton, L8N 4A6, Canada

RECRUITING

Anthos Investigative Site 2028

Markham, L3P7P3, Canada

RECRUITING

Anthos Investigative Site 2014

Montreal, H1T 1C8, Canada

RECRUITING

Anthos Investigative Site 2004

New Westminster, V3L 3W4, Canada

WITHDRAWN

Anthos Investigative Site 2021

North Vancouver, V7M 2H4, Canada

RECRUITING

Anthos Investigative Site 2002

Québec, G1R 2J6, Canada

RECRUITING

Anthos Investigative Site 2024

Saint Catharines, L2P 2W8, Canada

RECRUITING

Anthos Investigative Site 2006

Saint-Jérôme, J7Z 5T3, Canada

WITHDRAWN

Anthos Investigative Site 2027

Terrebonne, J6V 2H2, Canada

RECRUITING

Anthos Investigative Site 2022

Thunder Bay, P7B 5N3, Canada

RECRUITING

Anthos Investigative Site 2017

Toronto, M4N 3M5, Canada

RECRUITING

Anthos Investigative Site 2020

Toronto, M4N 3M5, Canada

RECRUITING

Anthos Investigative Site 2023

Toronto, M5S 1B2, Canada

RECRUITING

Anthos Investigative Site 1605

Concepción, 4030000, Chile

RECRUITING

Anthos Investigative Site 1606

Independencia, 8380465, Chile

RECRUITING

Anthos Investigative Site 1604

Providencia, 7500739, Chile

RECRUITING

Anthos Investigative Site 1607

San Bernardo, 8050000, Chile

RECRUITING

Anthos Investigative Site 1609

San Miguel, 8900000, Chile

RECRUITING

Anthos Investigative Site 1608

Santiago, 8320000, Chile

RECRUITING

Anthos Investigative Site 1610

Talcahuano, 4270918, Chile

RECRUITING

Anthos Investigative Site 1603

Temuco, 4780000, Chile

RECRUITING

Anthos Investigative Site 1602

Temuco, 4810345, Chile

RECRUITING

Anthos Investigative Site 1601

Viña del Mar, 2520997, Chile

RECRUITING

Anthos Investigational site 1825

Beijing, Beijing Municipality, 100029, China

RECRUITING

Anthos Investigational Site 1826

Beijing, Beijing Municipality, 100037, China

RECRUITING

Anthos Investigational Site 1832

Beijing, BJ, 100191, China

RECRUITING

Anthos Investigational site 1841

Lanzhou, Gansu, 730030, China

RECRUITING

Anthos Investigational site 1839

Guangzhou, Guangdong, 510080, China

ACTIVE NOT RECRUITING

Anthos Investigative Site 1834

Shantou, Guangdong, 515041, China

RECRUITING

Anthos Investigative Site 1833

Nanning, Guangxi, 530021, China

RECRUITING

Anthos Investigational Site 1846

Shijiazhuang, Hebei, 50031, China

RECRUITING

Anthos Investigative Site 1837

Wuhan, Hubei, 430014, China

RECRUITING

Anthos Investigational site 1831

Changchun, Jilin, 130033, China

RECRUITING

Anthos Investigational site 1842

Nanjing, JS, 210029, China

RECRUITING

Anthos Investigational site 1836

Shenzhen, Nanshan, 518057, China

RECRUITING

Anthos Investigational site 1823

Xi'an, Shaanxi, 7100061, China

RECRUITING

Anthos Investigative Site 1821

Xi'an, Shaanxi, 710068, China

RECRUITING

Anthos Investigational site 1822

Jinning, Shandong, 272111, China

RECRUITING

Anthos Investigational site 1843

Shanxi, Shanxi, 30001, China

RECRUITING

Anthos Investigational site 1835

ChongQing, Sichuan, 400010, China

ACTIVE NOT RECRUITING

Anthos Investigational site 1845

Tianjin, Tianjin Municipality, 300052, China

RECRUITING

Anthos Investigational Site 1830

Wenzhou, Zhejiang, 325035, China

RECRUITING

Anthos Investigative Site 1818

Changchun, 130021, China

WITHDRAWN

Anthos Investigative Site 1810

Changsha, 410005, China

RECRUITING

Anthos Investigative Site 1811

Changsha, 410013, China

RECRUITING

Anthos Investigative Site 1802

Chengdu, 610500, China

RECRUITING

Anthos Investigative Site 1829

Guangzhou, 510515, China

RECRUITING

Anthos Investigative Site 1809

Haidian, 10080, China

RECRUITING

Anthos Investigative Site 1801

Hangzhou, 310009, China

RECRUITING

Anthos Investigative Site 1808

Hangzhou, 310016, China

WITHDRAWN

Anthos Investigative Site 1816

Jinan, 250013, China

RECRUITING

Anthos Investigative Site 1804

Lianyungang, 222002, China

RECRUITING

Anthos Investigative Site 1814

Luoyang, 471003, China

RECRUITING

Anthos Investigative Site 1817

Nanchang, 330006, China

RECRUITING

Anthos Investigative Site 1820

Nanchang, 330009, China

RECRUITING

Anthos Investigative Site 1803

Nanjing, 210008, China

RECRUITING

Anthos Investigative Site 1815

Ningbo, 315016, China

WITHDRAWN

Anthos Investigational Site 1827

Shanghai, 200080, China

RECRUITING

Anthos Investigative Site 1819

Shijiazhuang, 50004, China

RECRUITING

Anthos Investigative Site 1812

Tianjin, 300121, China

RECRUITING

Anthos Investigative Site 1813

Yangzhou, 225012, China

RECRUITING

Anthos Investigative Site 1805

Yinchuan, 750001, China

RECRUITING

Anthos Investigational site 2509

Medellín, Antioquia, 50034, Colombia

RECRUITING

Anthos Investigative Site 2501

Manizales, Caldas Department, 170004, Colombia

RECRUITING

Anthos Investigative Site 2503

Armenia, QUI, 630004, Colombia

RECRUITING

Anthos Investigative Site 2513

Barranquilla, 80012, Colombia

RECRUITING

Anthos Investigative Site 2504

Barranquilla, 80020, Colombia

RECRUITING

Anthos Investigative Site 2512

Barranquilla, 80020, Colombia

RECRUITING

Anthos Investigative Site 2511

Cali, 760032, Colombia

RECRUITING

Anthos Investigative Site 2507

Cartagena, 130010, Colombia

RECRUITING

Anthos Investigative Site 2506

Floridablanca, 681004, Colombia

RECRUITING

Anthos Investigative Site 2508

Medellín, 50015, Colombia

RECRUITING

Anthos Investigative Site 2502

Pereira, 660003, Colombia

RECRUITING

Anthos Investigative Site 2510

Piedecuesta, 681017, Colombia

RECRUITING

Anthos Investigative Site 2505

Soledad, 083001, Colombia

RECRUITING

Anthos Investigative Site 3102

Krapinske Toplice, 49217, Croatia

RECRUITING

Anthos Investigative Site 3108

Osijek, 31000, Croatia

RECRUITING

Anthos Investigative Site 3107

Rijeka, 51000, Croatia

RECRUITING

Anthos Investigative Site 3111

Zabok, 49210, Croatia

RECRUITING

Anthos Investigative Site 3109

Zadar, 23000, Croatia

RECRUITING

Anthos Investigative Site 3101

Zagreb, 10000, Croatia

RECRUITING

Anthos Investigative Site 3103

Zagreb, 10000, Croatia

RECRUITING

Anthos Investigative Site 3104

Zagreb, 10000, Croatia

RECRUITING

Anthos Investigative Site 3110

Zagreb, 10000, Croatia

RECRUITING

Anthos Investigative Site 3002

Brandýs nad Labem, 250 01, Czechia

RECRUITING

Anthos Investigative Site 3006

Liberec, 460 01, Czechia

RECRUITING

Anthos Investigative Site 3007

Ostrava - Poruba, 70868, Czechia

RECRUITING

Anthos Investigative Site 3001

Poděbrady, 29001, Czechia

RECRUITING

Anthos Investigative Site 3005

Prague, 100 34, Czechia

RECRUITING

Anthos Investigative Site 3004

Prague, 128 00, Czechia

RECRUITING

Anthos Investigative Site 3003

Prague, 128 08, Czechia

RECRUITING

Anthos Investigative Site 3010

Prague, 150 06, Czechia

RECRUITING

Anthos Investigative Site 3009

Trutnov, 541 01, Czechia

RECRUITING

Anthos Investigative Site 3011

Ústí nad Labem, 400 11, Czechia

RECRUITING

Anthos Investigative Site 2203

Tallinn, 10138, Estonia

WITHDRAWN

Anthos Investigative Site 2202

Tallinn, 10617, Estonia

RECRUITING

Anthos Investigative Site 2201

Tallinn, 13419, Estonia

RECRUITING

Anthos Investigational site 3402

Helsinki, Uusimaa, 29, Finland

ACTIVE NOT RECRUITING

Anthos Investigative Site 3401

Joensuu, 80210, Finland

RECRUITING

Anthos Investigative Site 3403

Turku, 20520, Finland

RECRUITING

Anthos Investigative Site 7006

Altenburg, 4600, Germany

RECRUITING

Anthos Investigative Site 7014

Berlin, 10117, Germany

WITHDRAWN

Anthos Investigative Site 7004

Dresden, 01069, Germany

WITHDRAWN

Anthos Investigative Site 7012

Hamburg, 20246, Germany

RECRUITING

Anthos Investigative Site 7003

Hamburg, 20253, Germany

WITHDRAWN

Anthos Investigative Site 7013

Hanover, 30159, Germany

WITHDRAWN

Anthos Investigative Site 7009

Ludwigshafen, 67063, Germany

WITHDRAWN

Anthos Investigative Site 7002

Markkleeberg, 04416, Germany

RECRUITING

Anthos Investigative Site 7007

Paderborn, 33098, Germany

RECRUITING

Anthos Investigative Site 7001

Schwerin, 19055, Germany

WITHDRAWN

Anthos Investigational site 2713

Haidari, WA, 12462, Greece

ACTIVE NOT RECRUITING

Anthos Investigative Site 2714

Athens, 11521, Greece

RECRUITING

Anthos Investigative Site 2711

Athens, 14233, Greece

RECRUITING

Anthos Investigative Site 2704

Athens, 15669, Greece

RECRUITING

Anthos Investigative Site 2702

Cholargós, 155 62, Greece

RECRUITING

Anthos Investigative Site 2705

Glyfada, 166 75, Greece

RECRUITING

Anthos Investigative Site 2706

Larissa, 41110, Greece

RECRUITING

Anthos Investigational site 2703

Magoula, 19018, Greece

RECRUITING

Anthos Investigative Site 2712

Marousi, 12462, Greece

RECRUITING

Anthos Investigative Site 2715

Rio, 26504, Greece

RECRUITING

Anthos Investigative Site 2709

Thessaloniki, 546 36, Greece

RECRUITING

Anthos Investigative Site 2708

Thessaloniki, 54636, Greece

RECRUITING

Anthos Investigative Site 2710

Voula, 166 73, Greece

RECRUITING

Anthos Investigative Site 4002

Békéscsaba, 5600, Hungary

RECRUITING

Anthos Investigative Site 4015

Budapest, 1021, Hungary

WITHDRAWN

Anthos Investigative Site 4006

Budapest, 1036, Hungary

WITHDRAWN

Anthos Investigative Site 4009

Budapest, 1088, Hungary

RECRUITING

Anthos Investigative Site 4018

Budapest, 1132, Hungary

RECRUITING

Anthos Investigative Site 4014

Budapest, 1134, Hungary

RECRUITING

Anthos Investigative Site 4011

Gyöngyös, 3200, Hungary

WITHDRAWN

Anthos Investigative Site 4012

Kaposvár, 7400, Hungary

WITHDRAWN

Anthos Investigative Site 4007

Kistarcsa, 2143, Hungary

RECRUITING

Anthos Investigative Site 4005

Nyíregyháza, 4400, Hungary

WITHDRAWN

Anthos Investigative Site 4010

Pécs, 7623, Hungary

WITHDRAWN

Anthos Investigative Site 4017

Szeged, 6725, Hungary

RECRUITING

Anthos Investigative Site 4016

Veszprém, 8200, Hungary

RECRUITING

Anthos Investigative Site 4008

Zalaegerszeg, 8900, Hungary

WITHDRAWN

Anthos Investigative Site 2340

Kochi, Kerala, 682040, India

RECRUITING

Anthos Investigational site 2344

Rudrapur, UK, 263153, India

RECRUITING

Anthos Investigative Site 2310

Ahmedabad, 380054, India

RECRUITING

Anthos Investigative Site 2320

Ahmedabad, 380060, India

RECRUITING

Anthos Investigative Site 2330

Ajmer, 305001, India

RECRUITING

Anthos Investigative Site 2311

Bangalore, 560002, India

RECRUITING

Anthos Investigative Site 2318

Bhubaneswar, 751019, India

RECRUITING

Anthos Investigative Site 2303

Chandigarh, 160012, India

RECRUITING

Anthos Investigative Site 2324

Chennai, 600 037, India

RECRUITING

Anthos Investigative Site 2338

Chennai, 600017, India

RECRUITING

Anthos Investigative Site 2325

Chennai, 600024, India

RECRUITING

Anthos Investigative Site 2328

Dehradun, 248001, India

RECRUITING

Anthos Investigative Site 2308

Ghaziabad, 201010, India

WITHDRAWN

Anthos Investigative Site 2333

Hyderabad, 500032, India

RECRUITING

Anthos Investigative Site 2306

Jaipur, 302005, India

RECRUITING

Anthos Investigative Site 2331

Jaipur, 302039, India

RECRUITING

Anthos Investigative Site 2304

Kochi, 682001, India

WITHDRAWN

Anthos Investigative Site 2314

Kolkata, 700020, India

RECRUITING

Anthos Investigative Site 2323

Ludhiāna, 141001, India

RECRUITING

Anthos Investigative Site 2326

Mangaluru, 575002, India

RECRUITING

Anthos Investigative Site 2329

Meerut, 250005, India

RECRUITING

Anthos Investigative Site 2313

Mumbai, 400016, India

WITHDRAWN

Anthos Investigative Site 2315

Nagpur, 440001, India

RECRUITING

Anthos Investigative Site 2336

Nagpur, 440010, India

RECRUITING

Anthos Investigative Site 2316

Nagpur, 440022, India

RECRUITING

Anthos Investigative Site 2307

New Delhi, 110001, India

RECRUITING

Anthos Investigative Site 2301

New Delhi, 110002, India

RECRUITING

Anthos Investigative Site 2319

New Delhi, 110029, India

RECRUITING

Anthos Investigative Site 2327

New Delhi, 110029, India

RECRUITING

Anthos Investigative Site 2322

New Delhi, 110060, India

RECRUITING

Anthos Investigative Site 2305

Pune, 411004, India

RECRUITING

Anthos Investigative Site 2317

Pune, 411028, India

RECRUITING

Anthos Investigative Site 2309

Secunderabad, 500003, India

WITHDRAWN

Anthos Investigative Site 2312

Visakhapatnam, 530017, India

RECRUITING

Anthos Investigative Site 2321

Visakhapatnam, 531011, India

RECRUITING

Anthos Investigative Site 1210

Afula, 18101, Israel

RECRUITING

Anthos Investigative Site 1205

Ashkelon, 7827804, Israel

RECRUITING

Anthos Investigative Site 1213

Beersheba, 8489507, Israel

RECRUITING

Anthos Investigative Site 1206

Hadera, 38100, Israel

RECRUITING

Anthos Investigative Site 1211

Haifa, 31048, Israel

WITHDRAWN

Anthos Investigative Site 1201

Haifa, 3109601, Israel

WITHDRAWN

Anthos Investigative Site 1209

Holon, 58100, Israel

RECRUITING

Anthos Investigative Site 1212

Jerusalem, 91999, Israel

RECRUITING

Anthos Investigative Site 1204

Kfar Saba, 44281, Israel

RECRUITING

Anthos Investigative Site 1202

Nahariya, 22100, Israel

RECRUITING

Anthos Investigative Site 1207

Petah Tikva, 49100, Israel

RECRUITING

Anthos Investigative Site 1203

Rehovot, 7610001, Israel

RECRUITING

Anthos Investigative Site 1208

Safed, 13110, Israel

RECRUITING

Anthos Investigative Site 8016

Ancona, 60129, Italy

RECRUITING

Anthos Investigative Site 8003

Bologna, 40138, Italy

WITHDRAWN

Anthos Investigative Site 8015

Brescia, 25123, Italy

RECRUITING

Anthos Investigative Site 8020

Cagliari, 9121, Italy

RECRUITING

Anthos Investigative Site 8019

Caserta, 81100, Italy

RECRUITING

Anthos Investigative Site 8008

Catanzaro, 88100, Italy

WITHDRAWN

Anthos Investigative Site 8021

Cinisello Balsamo, 20092, Italy

RECRUITING

Anthos Investigative Site 8024

Florence, 50134, Italy

RECRUITING

Anthos Investigative Site 8013

Lecco, 23900, Italy

RECRUITING

Anthos Investigative Site 8007

Milan, 20138, Italy

WITHDRAWN

Anthos Investigative Site 8001

Milan, 20162, Italy

RECRUITING

Anthos Investigative Site 8026

Naples, 80100, Italy

RECRUITING

Anthos Investigative Site 8023

Naples, 80131, Italy

RECRUITING

Anthos Investigative Site 8017

Palermo, 90127, Italy

RECRUITING

Anthos Investigative Site 8025

Pisa, 56124, Italy

RECRUITING

Anthos Investigative Site 8029

Pisa, 56126, Italy

RECRUITING

Anthos Investigative Site 8031

Ravenna, 48182, Italy

RECRUITING

Anthos Investigative Site 8030

Rimini, 47923, Italy

RECRUITING

Anthos Investigative Site 8028

Rivoli, 10098, Italy

RECRUITING

Anthos Investigative Site 8010

Roma, 00152, Italy

RECRUITING

Anthos Investigative Site 8011

Roma, 00163, Italy

WITHDRAWN

Anthos Investigative Site 8002

Roma, 161, Italy

WITHDRAWN

Anthos Investigative Site 8022

Rome, 00168, Italy

RECRUITING

Anthos Investigational Site 8027

Rome, 189, Italy

RECRUITING

Anthos Investigative Site 8004

Saronno, 21052, Italy

RECRUITING

Anthos Investigative Site 8005

Sesto San Giovanni, 20099, Italy

RECRUITING

Anthos Investigative Site 8014

Torino, 10128, Italy

RECRUITING

Anthos Investigative Site 8006

Varese, 21100, Italy

RECRUITING

Anthos Investigative Site 8009

Vittoria, 97019, Italy

RECRUITING

Anthos Investigative Site 1923

Akashi, 674-0063, Japan

RECRUITING

Anthos Investigative Site 1908

Chikushino-shi, 818-8516, Japan

RECRUITING

Anthos Investigative Site 1902

Chūōku, 103-0027, Japan

RECRUITING

Anthos Investigative Site 1920

Funabashi-Shi, 273-8588, Japan

WITHDRAWN

Anthos Investigative Site 1910

Hamada-shi, 697-8511, Japan

RECRUITING

Anthos Investigative Site 1924

Hamamatsu, 432-8580, Japan

RECRUITING

Anthos Investigative Site 1906

Himeji-Shi, 670-0836, Japan

WITHDRAWN

Anthos Investigative Site 1911

Imabari, 799-1502, Japan

RECRUITING

Anthos Investigative Site 1912

Isehara-Shi, 259-1193, Japan

RECRUITING

Anthos Investigative Site 1921

Kōtoku, 135-0061, Japan

RECRUITING

Anthos Investigative Site 1915

Kure-shi, 737-8505, Japan

RECRUITING

Anthos Investigative Site 1931

Matsue, 690-8509, Japan

RECRUITING

Anthos Investigative Site 1903

Matsumoto-Shi, 390-8621, Japan

RECRUITING

Anthos Investigative Site 1907

Nagano, 380-0814, Japan

WITHDRAWN

Anthos Investigative Site 1929

Naha, 902-8511, Japan

RECRUITING

Anthos Investigative Site 1934

Okayama, 7008607, Japan

RECRUITING

Anthos Investigative Site 1932

Osaka, 545-8586, Japan

RECRUITING

Anthos Investigative Site 1930

Osaka, 559-0012, Japan

RECRUITING

Anthos Investigative Site 1926

Ōmihachiman, 523-0082, Japan

RECRUITING

Anthos Investigative Site 1922

Sapporo, 063-0005, Japan

RECRUITING

Anthos Investigative Site 1904

Sendai, 983-8520, Japan

RECRUITING

Anthos Investigative Site 1913

Shimonoseki-shi, 752-8510, Japan

WITHDRAWN

Anthos Investigative Site 1914

Tachikawa-shi, 190-0014, Japan

RECRUITING

Anthos Investigative Site 1909

Tochigi, 321-0293, Japan

RECRUITING

Anthos Investigative Site 1925

Tokushima, 770-8503, Japan

RECRUITING

Anthos Investigative Site 1933

Tokyo, 176-8530, Japan

RECRUITING

Anthos Investigative Site 1928

Toyama, 930-0194, Japan

RECRUITING

Anthos Investigative Site 1927

Tōon, 791-0281, Japan

RECRUITING

Anthos Investigative Site 1901

Urayasu, 279-0001, Japan

RECRUITING

Anthos Investigative Site 1917

Uwajima-Shi, 798-8510, Japan

RECRUITING

Anthos Investigative Site 1918

Yokohama, 232-0024, Japan

RECRUITING

Anthos Investigative Site 1919

Yokohama, 236-0037, Japan

RECRUITING

Anthos Investigative Site 1916

Yokohama, 245-8575, Japan

RECRUITING

Anthos Investigative Site 2103

Baldone, LV-2125, Latvia

WITHDRAWN

Anthos Investigative Site 2109

Balvi, LV-4501, Latvia

WITHDRAWN

Anthos Investigative Site 2107

Daugavpils, LV-5417, Latvia

RECRUITING

Anthos Investigative Site 2108

Limbaži, LV-4001, Latvia

WITHDRAWN

Anthos Investigative Site 2110

Riga, 1001, Latvia

RECRUITING

Anthos Investigative Site 2101

Riga, 1024, Latvia

RECRUITING

Anthos Investigative Site 2105

Riga, LV-1002, Latvia

RECRUITING

Anthos Investigative Site 2102

Riga, LV-1038, Latvia

RECRUITING

Anthos Investigative Site 2111

Sigulda, LV-2150, Latvia

RECRUITING

Anthos Investigative Site 2104

Valmiera, 4201, Latvia

WITHDRAWN

Anthos Investigative Site 2106

Valmiera, 4201, Latvia

RECRUITING

Anthos Investigative Site 3513

Alor Star, 5460, Malaysia

RECRUITING

Anthos Investigative Site 3501

Kajang, 43000, Malaysia

RECRUITING

Anthos Investigative Site 3505

Kuala Lumpur, 59100, Malaysia

RECRUITING

Anthos Investigative Site 3508

Kuantan, 25100, Malaysia

RECRUITING

Anthos Investigative Site 3511

Kuantan, 25200, Malaysia

RECRUITING

Anthos Investigative Site 3510

Kuching, 93586, Malaysia

RECRUITING

Anthos Investigative Site 3503

Kuching, 94300, Malaysia

RECRUITING

Anthos Investigative Site 3506

Miri, 98000, Malaysia

RECRUITING

Anthos Investigative Site 3509

Putrajaya, 62150, Malaysia

RECRUITING

Anthos Investigative Site 3502

Seberang Jaya, 13700, Malaysia

RECRUITING

Anthos Investigative Site 3507

Seremban, 70300, Malaysia

RECRUITING

Anthos Investigative Site 3512

Sibu, 96000, Malaysia

RECRUITING

Anthos Investigative Site 3504

Sungai Buloh, 47000, Malaysia

RECRUITING

Anthos Investigative Site 1701

Aguascalientes, 20230, Mexico

RECRUITING

Anthos Investigative Site 1707

Aguascalientes, 20230, Mexico

WITHDRAWN

Anthos Investigative Site 1713

Aguascalientes, 20230, Mexico

RECRUITING

Anthos Investigative Site 1721

Chihuahua City, 31200, Mexico

RECRUITING

Anthos Investigative Site 1703

Culiacán, 80230, Mexico

RECRUITING

Anthos Investigative Site 1715

Guadalajara, 44670, Mexico

RECRUITING

Anthos Investigative Site 1711

Guerrero, 39901, Mexico

RECRUITING

Anthos Investigative Site 1712

Mexico City, 03100, Mexico

RECRUITING

Anthos Investigative Site 1704

Monterrey, 64000, Mexico

RECRUITING

Anthos Investigative Site 1705

Monterrey, 64718, Mexico

RECRUITING

Anthos Investigative Site 1719

Monterrey, 64718, Mexico

RECRUITING

Anthos Investigative Site 1702

Querétaro, 76000, Mexico

RECRUITING

Anthos Investigative Site 1718

San Luis Potosí City, 78200, Mexico

RECRUITING

Anthos Investigative Site 1716

Tlalpan, 14080, Mexico

RECRUITING

Anthos Investigative Site 1706

Veracruz, 91900, Mexico

RECRUITING

Anthos Investigative Site 1708

Veracruz, 91900, Mexico

RECRUITING

Anthos Investigative Site 1709

Xalapa, 91193, Mexico

RECRUITING

Anthos Investigational site 3704

San Isidro, Lima region, L-27, Peru

RECRUITING

Anthos Investigative Site 3703

San Isidro, Lima region, LIMA 33, Peru

RECRUITING

Anthos Investigative Site 3706

Piura, 20001, Peru

RECRUITING

Anthos Investigative Site 3708

San Borja, 15036, Peru

RECRUITING

Anthos Investigational Site 3605

Manila, Manila, 1000, Philippines

RECRUITING

Anthos Investigative Site 3603

Angeles City, 2009, Philippines

RECRUITING

Anthos Investigational site 3602

City of Muntinlupa, 1780, Philippines

RECRUITING

Anthos Investigative Site 3601

Davao City, 8000, Philippines

RECRUITING

Anthos Investigative Site 3608

Iloilo City, 5000, Philippines

RECRUITING

Anthos Investigative Site 3610

Lahug, 6000, Philippines

RECRUITING

Anthos Investigative Site 3604

Lipa City, 4217, Philippines

RECRUITING

Anthos Investigational site 3609

Pasig, 1600, Philippines

RECRUITING

Anthos Investigational site 3607

Quezon City, 1109, Philippines

RECRUITING

Anthos Investigational site 3606

San Juan City, 1502, Philippines

RECRUITING

Anthos Investigative Site 5029

Bialystok, 15-276, Poland

RECRUITING

Anthos Investigative Site 5022

Czeladź, 41-250, Poland

RECRUITING

Anthos Investigative Site 5033

Elblag, 82-300, Poland

RECRUITING

Anthos Investigative Site 5010

Gdynia, 81-519, Poland

RECRUITING

Anthos Investigative Site 5034

Gdynia, 81-537, Poland

RECRUITING

Anthos Investigative Site 5003

Katowice, 40-083, Poland

RECRUITING

Anthos Investigative Site 5009

Katowice, 40-555, Poland

RECRUITING

Anthos Investigative Site 5030

Katowice, 40-635, Poland

RECRUITING

Anthos Investigative Site 5005

Katowice, 40-752, Poland

RECRUITING

Anthos Investigative Site 5016

Krakow, 30-688, Poland

RECRUITING

Anthos Investigative Site 5018

Krakow, 31- 501, Poland

WITHDRAWN

Anthos Investigative Site 5032

Legnica, 59-220, Poland

RECRUITING

Anthos Investigative Site 5021

Lodz, 91-002, Poland

RECRUITING

Anthos Investigative Site 5012

Lodz, 91-363, Poland

WITHDRAWN

Anthos Investigational Site 5040

Lodz, 92-213, Poland

RECRUITING

Anthos Investigative Site 5028

Lodz, 94-046, Poland

RECRUITING

Anthos Investigative Site 5023

Lublin, 20-049, Poland

RECRUITING

Anthos Investigative Site 5006

Lublin, 20-954, Poland

WITHDRAWN

Anthos Investigative Site 5039

Mielec, 39-300, Poland

RECRUITING

Anthos Investigative Site 5041

Nowa Sól, 67-100, Poland

RECRUITING

Anthos Investigative Site 5008

Olsztyn, 10-010, Poland

RECRUITING

Anthos Investigative Site 5025

Oświęcim, 32-600, Poland

RECRUITING

Anthos Investigative Site 5002

Przemyśl, 37-700, Poland

RECRUITING

Anthos Investigative Site 5004

Rzeszów, 35-055, Poland

RECRUITING

Anthos Investigative Site 5001

Tychy, 43-100, Poland

RECRUITING

Anthos Investigative Site 5014

Warsaw, 00-215, Poland

RECRUITING

Anthos Investigative Site 5038

Warsaw, 00-710, Poland

RECRUITING

Anthos Investigative Site 5017

Warsaw, 02-097, Poland

RECRUITING

Anthos Investigative Site 5011

Warsaw, 02-637, Poland

RECRUITING

Anthos Investigative Site 5015

Warsaw, 03-291, Poland

RECRUITING

Anthos Investigative Site 5019

Wroclaw, 51-162, Poland

RECRUITING

Anthos Investigative Site 5007

Wroclaw, 53-673, Poland

WITHDRAWN

Anthos Investigative Site 5024

Zabrze, 41-800, Poland

RECRUITING

Anthos Investigative Site 9022

Baloteşti, 077015, Romania

RECRUITING

Anthos Investigative Site 9028

Brasov, 500102, Romania

RECRUITING

Anthos Investigative Site 9001

Brăila, 810325, Romania

WITHDRAWN

Anthos Investigative Site 9023

Bucharest, 12296, Romania

RECRUITING

Anthos Investigative Site 9019

Bucharest, 14461, Romania

WITHDRAWN

Anthos Investigative Site 9031

Bucharest, 21337, Romania

RECRUITING

Anthos Investigative Site 9024

Cluj-Napoca, 400139, Romania

RECRUITING

Anthos Investigative Site 9017

Craiova, 200513, Romania

RECRUITING

Anthos Investigative Site 9006

Craiova, 200642, Romania

RECRUITING

Anthos Investigative Site 9010

Oradea, 410169, Romania

RECRUITING

Anthos Investigative Site 9025

Piteşti, 110003, Romania

RECRUITING

Anthos Investigative Site 9014

Piteşti, 110424, Romania

RECRUITING

Anthos Investigative Site 9012

Satu Mare, 440055, Romania

WITHDRAWN

Anthos Investigative Site 9003

Târgu Mureş, 540124, Romania

WITHDRAWN

Anthos Investigative Site 9004

Târgu Mureş, 540136, Romania

RECRUITING

Anthos Investigative Site 9016

Târgu Mureş, 540136, Romania

RECRUITING

Anthos Investigative Site 9021

Târgu Mureş, 540143, Romania

RECRUITING

Anthos Investigative Site 9007

Timișoara, 300079, Romania

RECRUITING

Anthos Investigative Site 9005

Timișoara, 300310, Romania

RECRUITING

Anthos Investigative Site 9018

Timișoara, 300310, Romania

WITHDRAWN

Anthos Investigative Site 9013

Timișoara, 300362, Romania

RECRUITING

Anthos Investigative Site 9008

Timișoara, 300480, Romania

RECRUITING

Anthos Investigative Site 2901

Belgrade, 11000, Serbia

RECRUITING

Anthos Investigative Site 2903

Belgrade, 11000, Serbia

RECRUITING

Anthos Investigative Site 2905

Belgrade, 11000, Serbia

RECRUITING

Anthos Investigative Site 2908

Belgrade, 11000, Serbia

RECRUITING

Anthos Investigative Site 2911

Belgrade, 11000, Serbia

RECRUITING

Anthos Investigative Site 2909

Belgrade, 11080, Serbia

RECRUITING

Anthos Investigative Site 2904

Kragujevac, 34000, Serbia

RECRUITING

Anthos Investigative Site 2912

Niš, 18000, Serbia

RECRUITING

Anthos Investigative Site 2910

Novi Pazar, 36300, Serbia

RECRUITING

Anthos Investigative Site 2906

Smederevo, 11300, Serbia

RECRUITING

Anthos Investigative Site 2902

Užice, 31000, Serbia

RECRUITING

Anthos Investigative Site 2907

Zaječar, 19000, Serbia

RECRUITING

Anthos Investigative Site 2801

Bardejov, 085 01, Slovakia

RECRUITING

Anthos Investigative Site 2807

Bratislava, 821 07, Slovakia

WITHDRAWN

Anthos Investigative Site 2805

Košice, 040 01, Slovakia

RECRUITING

Anthos Investigative Site 2806

Lučenec, 984 01, Slovakia

RECRUITING

Anthos Investigative Site 2809

Nové Zámky, 94002, Slovakia

RECRUITING

Anthos Investigative Site 2802

Piešťany, 921 01, Slovakia

RECRUITING

Anthos Investigative Site 2804

Žilina, 010 01, Slovakia

RECRUITING

Anthos Investigative Site 2411

Bellville, 7530, South Africa

RECRUITING

Anthos Investigative Site 2409

Benoni, 1501, South Africa

RECRUITING

Anthos Investigative Site 2417

Cape Town, 7580, South Africa

RECRUITING

Anthos Investigational site 2408

Centurion, 0157, South Africa

RECRUITING

Anthos Investigative Site 2408

Centurion, 0157, South Africa

RECRUITING

Anthos Investigative Site 2412

Durban, 4001, South Africa

RECRUITING

Anthos Investigative Site 2416

Johannesburg, 2182, South Africa

RECRUITING

Anthos Investigative Site 2402

Pretoria, 0181, South Africa

RECRUITING

Anthos Investigative Site 2414

Pretoria, 0184, South Africa

WITHDRAWN

Anthos Investigative Site 2415

Somerset West, 7130, South Africa

WITHDRAWN

Anthos Investigative Site 2405

Tongaat, 4400, South Africa

RECRUITING

Anthos Investigative Site 2609

Anyang-si, 14068, South Korea

RECRUITING

Anthos Investigative Site 2610

Busan, 47392, South Korea

RECRUITING

Anthos Investigative Site 2606

Busan, 49241, South Korea

RECRUITING

Anthos Investigative Site 2614

Daegu, 42472, South Korea

RECRUITING

Anthos Investigative Site 2613

Daejeon, 35015, South Korea

RECRUITING

Anthos Investigative Site 2615

Goyang-si, 10380, South Korea

RECRUITING

Anthos Investigative Site 2602

Gwangju, 61469, South Korea

RECRUITING

Anthos Investigative Site 2611

Gyeonggi-do, 13496, South Korea

RECRUITING

Anthos Investigative Site 2604

Seongnam-si, 13620, South Korea

RECRUITING

Anthos Investigative Site 2608

Seoul, 2841, South Korea

RECRUITING

Anthos Investigative Site 2617

Seoul, 3080, South Korea

RECRUITING

Anthos Investigative Site 2603

Seoul, 3312, South Korea

RECRUITING

Anthos Investigative Site 2601

Seoul, 3722, South Korea

RECRUITING

Anthos Investigative Site 2612

Seoul, 5505, South Korea

RECRUITING

Anthos Investigative Site 2616

Seoul, 8308, South Korea

RECRUITING

Anthos Investigative Site 2607

Ulsan, 44033, South Korea

RECRUITING

Anthos Investigative Site 2605

Yongin-si, 16995, South Korea

RECRUITING

Anthos Investigative Site 1108

A Coruña, 15006, Spain

WITHDRAWN

Anthos Investigative Site 1116

Almería, 04009, Spain

WITHDRAWN

Anthos Investigative Site 1121

Barcelona, 8035, Spain

RECRUITING

Anthos Investigative Site 1124

Barcelona, 8041, Spain

RECRUITING

Anthos Investigative Site 1120

Barcelona, 8902, Spain

RECRUITING

Anthos Investigative Site 1109

Cabra, 14940, Spain

RECRUITING

Anthos Investigative Site 1103

Granada, 18014, Spain

RECRUITING

Anthos Investigative Site 1111

Jaén, 23007, Spain

RECRUITING

Anthos Investigative Site 1118

León, 24071, Spain

RECRUITING

Anthos Investigative Site 1104

Madrid, 28003, Spain

RECRUITING

Anthos Investigative Site 1117

Madrid, 28010, Spain

RECRUITING

Anthos Investigative Site 1106

Madrid, 28035, Spain

WITHDRAWN

Anthos Investigative Site 1113

Madrid, 28046, Spain

WITHDRAWN

Anthos Investigative Site 1105

Málaga, 29010, Spain

WITHDRAWN

Anthos Investigative Site 1110

Murcia, 30120, Spain

RECRUITING

Anthos Investigative Site 1115

Oviedo, 33006, Spain

RECRUITING

Anthos Investigative Site 1123

Sabadell, 8208, Spain

RECRUITING

Anthos Investigative Site 1107

Santiago de Compostela, 15706, Spain

RECRUITING

Anthos Investigative Site 1102

Seville, 41009, Spain

RECRUITING

Anthos Investigative Site 1122

Seville, 41013, Spain

RECRUITING

Anthos Investigative Site 1112

Terrassa, 08221, Spain

WITHDRAWN

Anthos Investigative Site 1101

Valencia, 46010, Spain

RECRUITING

Anthos Investigative Site 1119

Vigo, 36213, Spain

RECRUITING

Anthos Investigative Site 3303

Danderyd, 182 88, Sweden

RECRUITING

Anthos Investigative Site 3302

Örebro, 70185, Sweden

RECRUITING

Anthos Investigative Site 3301

Stockholm, 117 27, Sweden

RECRUITING

Anthos Investigative Site 3303

Stockholm, 18288, Sweden

RECRUITING

Anthos Invesitgational site 3211

Adana, Adana, 1330, Turkey (Türkiye)

RECRUITING

Anthos Investigational site 3215

Adana, Adana, 4522, Turkey (Türkiye)

RECRUITING

Anthos Investigational site 3210

Istanbul, Istanbul, 34010, Turkey (Türkiye)

RECRUITING

Anthos Investigational site 3205

Izmir, İzmir, 35340, Turkey (Türkiye)

RECRUITING

Anthos Investigative Site 3203

Ankara, 06520, Turkey (Türkiye)

RECRUITING

Anthos Investigative Site 3207

Antalya, 7070, Turkey (Türkiye)

RECRUITING

Anthos Investigative Site 3201

Bursa, 16310, Turkey (Türkiye)

RECRUITING

Anthos Investigative Site 3208

Diyarbakır, 21070, Turkey (Türkiye)

RECRUITING

Anthos Investigative Site 3209

Istanbul, 34835, Turkey (Türkiye)

RECRUITING

Anthos Investigative Site 3202

Kayseri, 38039, Turkey (Türkiye)

RECRUITING

Anthos Investigative Site 3206

Mersin, 33110, Turkey (Türkiye)

RECRUITING

Anthos Investigative Site 3204

Samsun, 55090, Turkey (Türkiye)

RECRUITING

Anthos Investigational site 1327

Bollington, Cheshire, SK105JH, United Kingdom

RECRUITING

Anthos Investigational site 1329

Blackpool, Lancanshire, FY3 8NR, United Kingdom

RECRUITING

Anthos Investigational site 1328

Brierley Hill, West Midlands, DY5 1RU, United Kingdom

RECRUITING

Anthos Investigative Site 1303

Corby, NN17 2UR, United Kingdom

WITHDRAWN

Anthos Investigative Site 1313

Glasgow, G20 0XA, United Kingdom

WITHDRAWN

Anthos Investigative Site 1320

Glasgow, G51 4TF, United Kingdom

RECRUITING

Anthos Investigative Site 1315

Hayle, TR27 5DT, United Kingdom

RECRUITING

Anthos Investigative Site 1311

High Wycombe, HP11 2TT, United Kingdom

RECRUITING

Anthos Investigative Site 1301

Isleworth, TW7 6AF, United Kingdom

RECRUITING

Anthos Investigative Site 1316

Kings Lynn, PE30 4ET, United Kingdom

RECRUITING

Anthos Investigative Site 1324

Lancaster, LA1 4ZP, United Kingdom

RECRUITING

Anthos Investigative Site 1322

Larbert, FK5 4WR, United Kingdom

RECRUITING

Anthos Investigative Site 1309

Leeds, LS1 3EX, United Kingdom

RECRUITING

Anthos Investigative Site 1325

Liverpool, L14 3PE, United Kingdom

RECRUITING

Anthos Investigative Site 1314

London, IG1 4HP, United Kingdom

WITHDRAWN

Anthos Investigative Site 1319

London, NW1 5DH, United Kingdom

RECRUITING

Anthos Investigative Site 1326

London, NW10 2PT, United Kingdom

RECRUITING

Anthos Investigative Site 1308

London, SW3 6NP, United Kingdom

RECRUITING

Anthos Investigative Site 1323

Luton, LU4 0DZ, United Kingdom

RECRUITING

Anthos Investigative Site 1312

Manchester, M27 8FF, United Kingdom

RECRUITING

Anthos Investigative Site 1307

Newcastle upon Tyne, NE7 7DN, United Kingdom

WITHDRAWN

Anthos Investigative Site 1318

Norwich, NR2 2TJ, United Kingdom

RECRUITING

Anthos Investigational site 1330

Oxford, OX3 9JA, United Kingdom

RECRUITING

Anthos Investigative Site 1305

Peterborough, PE3 9GZ, United Kingdom

RECRUITING

Anthos Investigative Site 1321

Romford, RM7 0AG, United Kingdom

RECRUITING

Anthos Investigative Site 1302

Stevenage, SG1 4AB, United Kingdom

RECRUITING

Anthos Investigative Site 1310

Stockton-on-Tees, TS19 8PE, United Kingdom

RECRUITING

Anthos Investigative Site 1317

Stoke-on-Trent, ST4 6QG, United Kingdom

RECRUITING

Anthos Investigative Site 1306

Taunton, TA1 5DA, United Kingdom

WITHDRAWN

MeSH Terms

Conditions

Atrial Fibrillation

Interventions

abelacimab; MAA868

Condition Hierarchy (Ancestors)

Arrhythmias, Cardiac; Heart Diseases; Cardiovascular Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Anthos Therapeutics a Novartis Company

CONTACT

1-888-669-6682; novartis.email@novartis.com

Study Design

• Study Type: interventional
• Phase: phase 3
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 12, 2023
• First Posted: February 3, 2023
• Study Start: December 27, 2022
• Primary Completion (Estimated): August 31, 2026
• Study Completion (Estimated): October 31, 2026
• Last Updated: March 31, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will share

Locations

CL (10); FI (3); RO (22); CN (39); PE (4); PH (10); BU (31); ME (17); KR (17); IN (35); SL (7); CZ (10); GR (13); IL (13); LA (11); DE (10); AR (28); IT (29); HU (14); US (150); ZA (11); CO (13); CA (23); BR (43); PL (33); GB (29); JP (33); TU (12); CR (9); ES (23); SE (4); MY (13)