Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 45/100

Failure Rate

18.8%

582 terminated/withdrawn out of 3104 trials

Success Rate

78.0%

-8.5% vs industry average

Late-Stage Pipeline

37%

1135 trials in Phase 3/4

Results Transparency

67%

1384 of 2059 completed trials have results

Key Signals

200 recruiting1384 with results462 terminated120 withdrawn

Enrollment Performance

Analytics

Phase 2
896(33.2%)
Phase 3
740(27.4%)
Phase 1
613(22.7%)
Phase 4
395(14.6%)
N/A
46(1.7%)
Early Phase 1
7(0.3%)
2697Total
Phase 2(896)
Phase 3(740)
Phase 1(613)
Phase 4(395)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (3104)

Showing 20 of 3104 trials
NCT07206056Phase 1Recruiting

An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)

Role: lead

NCT06991556Phase 2Recruiting

An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Role: lead

NCT06958315Recruiting

Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study

Role: lead

NCT06331312Phase 3Active Not Recruiting

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)

Role: lead

NCT06813911Phase 3Recruiting

Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD

Role: lead

NCT07226986Phase 1Recruiting

A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC

Role: lead

NCT07326709Phase 3Recruiting

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

Role: lead

NCT06955169Phase 2Recruiting

Comparing the Radiopharmaceutical Drug, [177Lu]Lu-DOTATATE, to Standard of Care Treatment for Patients With Meningioma That Has Come Back After Prior Treatment

Role: collaborator

NCT06517732Active Not Recruiting

Study to Collect in a Real-world populatIon Data on the Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe Hidradenitis Suppurativa (HS) in Routine Clinical Practice in the Russian Federation

Role: lead

NCT02934568Phase 2Active Not Recruiting

Ribociclib (LEE011) Rollover Study for Continued Access

Role: lead

NCT03114319Phase 1Terminated

Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors

Role: lead

NCT07085767Phase 3Recruiting

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

Role: collaborator

NCT07357727Phase 3Recruiting

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

Role: lead

NCT05362903Completed

A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting

Role: lead

NCT05939414Phase 3Recruiting

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

Role: lead

NCT07229235Recruiting

REAL-CARE: Real-world Effectiveness of Iptacopan in Italian Patients With Paroxysmal Nocturnal Hemoglobinuria

Role: lead

NCT07358364Recruiting

Remibrutinib in Real-world Clinical Practice

Role: lead

NCT06780670Phase 2Recruiting

Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy

Role: lead

NCT06784752Phase 3Recruiting

Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET

Role: lead

NCT05921994Active Not Recruiting

Long Term Observational Study to Collect in a Real-world populatIon Data on the Treatment Pattern of secukinumAb in Adult Patients With Moderate to Severe Hidradenitis Suppurativa.

Role: lead