Monitoring Sleep, Wellbeing, and Glucose Metabolism in PGY1s

NCT05695235 | Unknown

• 1 other identifier: NUHSsleepstudy
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Overnight on-call schedules can impact sleep, wellbeing, and alertness, which can be detrimental on the performance, physical and mental health of residents. Moreover, rotating shift work may have a long-term negative health impact (e.g. increased risk of diabetes). Within the National University Hospital (NUH), two different systems of rotating on-call schedules are implemented. In the night float system, residents work from 8 pm to 8 am for 5 - 7 consecutive nights once every month, compared to the traditional overnight on-call system, where each resident is on call for 4-6 nights per month (7 am - 5 pm, followed by overnight call until 8 am the next morning). The aim of the current study is to track sleep, wellbeing, and glucose metabolism during the different phases of the night float and traditional on-call schedules.

Conditions

Sleep; Glucose Metabolism Disorders

Outcome Measures

Primary Outcomes (4)

• Sleep

  Sleep duration and timing will be measured

  8 weeks

• Wellbeing

  Participants will complete a daily micro questionnaire delivered through a mobile phone-based application. The investigators will examine mood ratings and stress ratings. Participants will be asked to respond to questions such as "How are you feeling right now?", rating their response from 'Negative' to 'Positive' on a 100-points sliding bar, "How stressed are you feeling right now?", rating their response from 'Not at all stressed' to 'Very stressed' on a 100-points sliding bar.

  8 weeks

• Glucose monitoring

  Blood glucose will be recorded using a wearable continuous glucose monitoring sensor (CGM: FreeStyle Libre Pro iQ by Abbott). CGM period will be individually scheduled to coincide with at least one cycle of day shift-night shift- recovery for each participant.

  2 weeks

• Alertness

  Participants will complete a daily set of cognitive games, delivered through a mobile phone-based application. The outcome measure from the games is a 3-min psychomotor vigilance task measuring sustained attention. Specifically, the investigators examine median reaction time and lapses (reaction time \> 500ms).

  8 weeks

Study Arms (2)

Traditional call

In the traditional overnight on-call system, each resident is on call for 4-6 nights per month (7 am - 5 pm, followed by overnight call until 8 am the next morning)

Device: CGM; Device: Oura ring; Behavioral: Cognitive tasks and questionnaires

Float call

In the night float system, residents work from 8 pm to 8 am for 5 - 7 consecutive nights once every month

Device: CGM; Device: Oura ring; Behavioral: Cognitive tasks and questionnaires

Interventions

CGM DEVICE

Wearable continuous glucose monitoring systems (CGMS) provide a minimally invasive means of passively tracking ambulant interstitial fluid glucose levels in real time.

Float call; Traditional call

Oura ring DEVICE

Wearable sleep tracking device

Float call; Traditional call

Cognitive tasks and questionnaires BEHAVIORAL

Participants will be prompted daily to fill out a short set of wellbeing questions and perform a short alertness test on their mobile phones and laptop.

Float call; Traditional call

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

NUHS Postgraduate year 1 doctors

You may qualify if:

• NUHS Postgraduate year 1 doctors
• Above 21 years of age
• Completing their year 1 rotations in 2021 or 2022

Sponsors & Collaborators

• National University of Singapore: lead

Study Sites (1)

National University of Singapore

Singapore, (No States Listed), 117597, Singapore

RECRUITING

MeSH Terms

Conditions

Glucose Metabolism Disorders

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Metabolic Diseases; Nutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Central Study Contacts

Stijn Agus Adrianus Massar, PhD

CONTACT

+65 66015238; mdcsaam@nus.edu.sg

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: December 27, 2022
• First Posted: January 23, 2023
• Study Start: January 1, 2022
• Primary Completion: June 1, 2023
• Study Completion: June 1, 2023
• Last Updated: January 25, 2023

Record last verified: 2023-01

Data Sharing

• IPD Sharing: Will not share

Locations

SG (1)