Impact of Obesity on Periodontal Health in a Sample of Adult Egyptian Patients: A Comparant Study

NCT05676736 | Completed

• 1 other identifier: Mai Zakaria Protocol
• Study Type: observational
• Target: 384
• Locations: 1 country
• Sites: 1

Brief Summary

Periodontal disease is defined as "an inflammatory disease of the tooth supportive structure caused by specific microorganisms or groups of specific microorganisms, resulting in progressive destruction of the periodontal ligament and alveolar bone with increased probing depth formation, recession, or both". According to WHO, overweight and obesity are defined as abnormal or excessive fat accumulation that may impair health. Body mass index (BMI) can be considered as an indicator of obesity-related health risks. Obesity was considered a global epidemic problem by the World Health Organization in the 1990s as it has increased internationally over the last decades. Based on review in 2003 the periodontal disease onset, progression and response to therapeutic interventions have been shown to be influenced by several systemic, local and environmental modifying factors and the data collected from the literature suggests that nutritional supplementation has been suggested as a possible influencing factor on periodontal status and wound healing.

Conditions

Obesity, Periodontal Health

Outcome Measures

Primary Outcomes (1)

• - The primary outcome of the study is the periodontal health in association with obesity

  The periodontal health status evaluated by full mouth charting using UNC 15 peiodontal probe, including probing depth (PD), clinical attachment Level (CAL), bleeding on probing (BOP), plaque index (PI).

  Day 1

Study Arms (2)

Study group (S) Obese group

Patients with body mass index (BMI) range from (≥30 kg/m2)

Other: No intervention

Control group (C) Normal weight group

Patients with body mass index (BMI) range from (18.5-24.9 kg/m2)

Other: No intervention

Interventions

No intervention OTHER

No intervention to be done for the group

Control group (C) Normal weight group; Study group (S) Obese group

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

\- Dental patients will be recruited in a consecutive manner from the outpatient Diagnostic center, Faculty of Dentistry, Cairo University.

You may qualify if:

• Patients whose age is between 18-60 years old.
• Provide informed consent.
• Patient have at least 20 natural teeth.
• Patient had no received periodontal treatment within previous 4 months.

You may not qualify if:

• Individuals with chronic systemic diseases such as cancer, osteoporosis, endocrine and hematological Pathologies.
• Patients having problem in opening their mouth or undergoing intermaxillary fixation where oral examination will not be possible.
• Pregnant women.
• Patients diagnosed with psychiatric problems or intoxicated with alcohol or drugs.
• Patients with orthodontic appliances.
• Patient had autoimmune condition.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Dentistry, Cairo University

Cairo, 115, Egypt

Location

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Mai Zakaria, ph

  Associate professor Oral Medicine & Periodontology, Faculty of Dentistry, Cairo University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor Oral Medicine & Periodontology

Study Record Dates

• First Submitted: December 31, 2022
• First Posted: January 9, 2023
• Study Start: December 1, 2022
• Primary Completion: April 20, 2023
• Study Completion: May 30, 2023
• Last Updated: September 21, 2023

Record last verified: 2023-09

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)