"Knee Joint Position Sense and Dynamic Balance in Females With Primary Dysmenorrhea

NCT07239232 | Recruiting

• 1 other identifier: P.T.REC/012/005972
• Study Type: observational
• Target: 62
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to assess knee joint position sense, pain and dynamic balance in female with primary dysmenorrhea.

Conditions

Primary Dysmenorrhea

Keywords

Knee; Position sense; Balance; Primary Dysmenorrhea

Outcome Measures

Primary Outcomes (4)

• Overall Stability Index (OSI) . Antero-posterior stability index score (APSI) . Medio lateral stability index score (MLSI) . Over all stability index score (OASI)

  The Overall Stability Index (OSI) is the primary measure of dynamic postural control obtained from the balance assessment system. It reflects the standard deviation of the participant's sway from the platform's center across both the medial-lateral and anterior-posterior directions. Higher OSI values indicate greater instability and poorer balance performance. As an integrated measure of sway variability, the OSI is considered the most comprehensive indicator of overall balance ability and is commonly used to evaluate changes in postural control in response to therapeutic interventions.

  at first and fourth menstrual days

• Medial-Lateral Stability Index (MLSI)

  The Medial-Lateral Stability Index (MLSI) quantifies the degree of side-to-side sway during balance testing. It represents the standard deviation of medial-lateral movement from the platform's center point, providing a directional measure of postural stability. Elevated MLSI scores reflect increased lateral instability, which may be associated with impaired neuromuscular control or deficits in weight-shifting ability. This variable is useful for identifying balance impairments that predominantly affect frontal plane stability.

  at first and fourth menstrual days

• Anterior-Posterior Stability Index (APSI)

  The Anterior-Posterior Stability Index (APSI) measures front-to-back sway during dynamic balance assessment. Calculated as the standard deviation of anterior-posterior deviations from the center of the platform, the APSI provides insight into sagittal plane stability. Higher APSI values indicate greater instability and reduced capacity to control forward and backward movements. This index is important for evaluating postural control related to gait, stepping, and activities requiring controlled anterior or posterior shifts in the center of gravity.

  at first and fourth menstrual days

• knee joint position sense

  using active knee position sense test by universal goniometer.

  at first and fourth menstrual days

Secondary Outcomes (1)

• knee joint pain

  at first and fourth menstrual days

Study Arms (2)

Asymptomatic Group

They have no or mild primary dysmenorrhea.

Other: No intervention

Symptomatic Group

They have moderate and sever primary dysmenorrhea.

Other: No intervention

Interventions

No intervention OTHER

No intervention

Asymptomatic Group; Symptomatic Group

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Sixty-two healthy female university students will participate in this study. They will be selected randomly from faculty of physical therapy, Cairo University.

You may qualify if:

• They should be virgin, healthy female students
• They have regular menstruation (3-8 days in duration, with 21-35 days in-between).
• They should have the same activity level mild active female.
• Their ages will range from 18 to 25 years old.
• Their body mass index (BMI) will range from 18 to 24.9 Kg/m2.

You may not qualify if:

• History of knee injury, surgery in the knee or spinal vertebrae.
• Females having any vestibular problems, otitis media, labyrinthitis or any inner ear problems that affect balance
• Women with any cognitive deficits
• History of neuromuscular or spinal disease.
• History of pelvic pathology or any gynecological disease.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Giza, Egypt

RECRUITING

Study Officials

• AFAF M BOTLA, PhD

  Assistant Professor, Cairo University

  STUDY CHAIR

• ELHAM s HASSAN, PhD

  Lecturer, Cairo university

  STUDY DIRECTOR

Central Study Contacts

Eman B ABDUL HAMID, B.Sc

CONTACT

01158876852; emanahmed2033e@gmail.com

ELHAM s HASSAN, PhD

CONTACT

01206146539; elhamramdan70@cu.edu.eg

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 16, 2025
• First Posted: November 20, 2025
• Study Start: November 18, 2025
• Primary Completion: January 20, 2026
• Study Completion: January 30, 2026
• Last Updated: December 12, 2025

Record last verified: 2025-12

Locations

EG (1)