Impact of Spinal Alignment on Pelvic Floor Efficiency

NCT07693465 | Completed

• 1 other identifier: P.T.REC/012/005314
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study was to determine the effect of spinal alignment on pelvic floor efficiency in nulliparous women.

Conditions

Pelvic Floor Disorders; Spinal Deformity

Outcome Measures

Primary Outcomes (1)

• Pelvic floor muscle strength

  Pelvic floor muscle strength was measured using vaginal pressure biofeedback (maximum voluntary contraction pressure).

  Baseline

Secondary Outcomes (4)

• Pelvic floor muscle endurance

  Baseline

• Spinal alignment angle

  Baseline

• Pelvic floor dysfunction symptoms

  Baseline

• Health-related quality of life

  Baseline

Study Arms (4)

Nulliparous women with thoracolumbar scoliosis

Twenty nulliparous women with thoracolumbar scoliosis. They will undergo assessment using Formetric analysis and vaginal pressure biofeedback.

Other: No Intervention

Nulliparous women with hyperlordosis

Twenty nulliparous women with hyperlordosis. They will undergo assessment using Formetric analysis and vaginal pressure biofeedback.

Other: No Intervention

Nulliparous women with thoracic kyphosis

Twenty nulliparous women with thoracic kyphosis. They will undergo assessment using Formetric analysis and vaginal pressure biofeedback.

Other: No Intervention

Nulliparous women with normal spinal alignment

Twenty nulliparous women with normal spinal alignment. They will undergo assessment using Formetric analysis and vaginal pressure biofeedback.

Other: No Intervention

Interventions

No Intervention OTHER

No Intervention

Nulliparous women with hyperlordosis; Nulliparous women with normal spinal alignment; Nulliparous women with thoracic kyphosis; Nulliparous women with thoracolumbar scoliosis

Eligibility Criteria

• Age: 25 Years - 35 Years
• Sex: female
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The study population consisted of 80 nulliparous women aged 25-35 years with different spinal alignment patterns (thoracolumbar scoliosis, hyperlordosis, thoracic kyphosis, or normal spinal alignment). Participants were recruited from the outpatient orthopedic clinic of Gesr El Suez, Cairo, Egypt. Eligible participants had a body mass index (BMI) of \<30 kg/m² and no history of pregnancy, spinal surgery, congenital spinal deformity, neuromuscular disorders, systemic diseases, malignancy, or urogenital disorders.

You may qualify if:

• Nulliparous women.
• Their ages will range from 25 to 35 years old.
• Their body mass index (BMI) will not exceed 29.9 Kg/m2.

You may not qualify if:

• Female with congenital spinal deformity.
• Female with a history of neuromuscular disease.
• Female Diagnosed with any systemic disease .
• Female with a history of malignancy and/or ongoing treatment.
• Female with a history of urogenital diseases and surgical history.
• Female with previous spinal surgery.
• Female with previous pregnancy .

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical Therapy, Cairo University

Giza, Egypt

Location

MeSH Terms

Conditions

Pelvic Floor Disorders

Condition Hierarchy (Ancestors)

Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Pregnancy Complications; Male Urogenital Diseases

Study Officials

• Afaf Mohamed Mahmoud Botla, PhD

  Professor, Cairo University

  STUDY CHAIR

• Amira Nagy Abd Ellatief Hamad, PhD

  Lecturer, Cairo University

  STUDY DIRECTOR

• Amal Abd Elrahman Mohamed Elborady

  Assist. Professor, Cairo University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: July 3, 2026
• First Posted: July 9, 2026
• Study Start: September 1, 2024
• Primary Completion: August 31, 2025
• Study Completion: August 31, 2025
• Last Updated: July 9, 2026

Record last verified: 2026-07

Locations

EG (1)