NCT05674955

Brief Summary

To compare between the effect of circuit weight and aerobic training on selected cardiovascular indices and functional capacity in patients with ischemic cardiomyopathy.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Aug 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 10, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

January 9, 2023

Completed
1.6 years until next milestone

Study Start

First participant enrolled

August 25, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 25, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 25, 2024

Completed
Last Updated

July 10, 2025

Status Verified

July 1, 2025

Enrollment Period

2 months

First QC Date

December 10, 2022

Last Update Submit

July 5, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Ejection fraction

    Will be measured by precentge

    2 months

Secondary Outcomes (1)

  • Blood pressure

    2 months

Study Arms (3)

Circuit weight group

EXPERIMENTAL
Diagnostic Test: Circuit weight versus aerobic training

Aerobic group

EXPERIMENTAL
Diagnostic Test: Circuit weight versus aerobic training

Control Group

EXPERIMENTAL
Diagnostic Test: Circuit weight versus aerobic training

Interventions

Circuit weight :Duration: 30 min-60 min (total session) Frequency: 3 times / week. Intensity: increased load was established when subject was able to complete 12 repetitions ( Wayne, 2014) B- Aerobic training: This mode of exercise will be conducted for study group B as follows: Intensity: started by 60-85% of target heart rate according to each patient response Target heart rate (THR) = 60% -85% (maximum heart rate-resting heart rate) + resting heart rate Maximum heart rate (MHR) = (220-Age). Mode: Walking on treadmill. Duration: Each session consisted of 10 minutes warming up firstly then 30 minutes time of session ended by 10 minutes cool down exercises. Frequency: Three times / week (Nishi et al., 2011). C-Traditional medical treatment: This treatment will be conducted for all group A, B and C.

Aerobic groupCircuit weight groupControl Group

Eligibility Criteria

Age45 Years - 55 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Sixty male patients with ischemic cardiomyopathy as a result of a recent acute myocardial infarction event (≤2 months) with 40%\<LVEF\<50%.
  • They are functionally classified as class II according to New York Heart Association (NYHA).
  • Their age will be ranged from 45 to 55 years old.
  • Their BMI will be ranged from 25 to 29.9 kg/m².
  • They will have good mentality.

You may not qualify if:

  • Recurrent coronary heart disease.
  • Severe valvular diseases.
  • Underlying pulmonary disease (aspiration pneumonia, chronic obstructive pulmonary disease, pneumothorax, etc.).
  • Inability to ambulate owing to physical problems (paresis induced by cerebral stroke, spinal cord injury, amputation, severe pain, dyspnea, etc.).
  • muskloskletal problems (e.g. severe osteoarthritis or ankylosing spondylitis).
  • Impaired cognitive function (vascular dementia, Alzheimer's dementia, other psychological disease, etc.)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cairo University

Giza, Egypt

Location

Related Publications (1)

  • Nishi I, Noguchi T, Iwanaga Y, Furuichi S, Aihara N, Takaki H, Goto Y. Effects of exercise training in patients with chronic heart failure and advanced left ventricular systolic dysfunction receiving beta-blockers. Circ J. 2011;75(7):1649-55. doi: 10.1253/circj.cj-10-0899. Epub 2011 May 25.

    PMID: 21613745BACKGROUND

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: 3 groups of ischemic cardiomyopathy patients. 1st group receive circuit weight training. 2nd group receive aerobic. 3rd group receive medications
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Domenstrator

Study Record Dates

First Submitted

December 10, 2022

First Posted

January 9, 2023

Study Start

August 25, 2024

Primary Completion

October 25, 2024

Study Completion

October 25, 2024

Last Updated

July 10, 2025

Record last verified: 2025-07

Locations