NCT05668169

Brief Summary

The goal of this study is to evaluate the effect of a family-centered support program on the care burden, depressive symptoms, perceived social support, and quality of life of stroke survivor' caregivers and on care recipients' rehabilitation adherence and depressive symptoms.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
210

participants targeted

Target at P75+ for not_applicable stroke

Timeline
Completed

Started Aug 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 16, 2021

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2022

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

December 13, 2022

Completed
16 days until next milestone

First Posted

Study publicly available on registry

December 29, 2022

Completed
Last Updated

December 29, 2022

Status Verified

December 1, 2022

Enrollment Period

1.2 years

First QC Date

December 13, 2022

Last Update Submit

December 20, 2022

Conditions

Keywords

family-centered intervention

Outcome Measures

Primary Outcomes (15)

  • Depressive symptoms

    Depressive symptoms were measured using the Taiwanese Depression Scale.The range of total scores is between 0\~54, the scores higher than 19 indicated an increased risk of depression.

    The outcome was assessed at baseline.

  • Caregiver care burden

    The caregiver strain index (CSI) was used to measure caregiver care burden. The range of total scores is between 0\~13, the higher total scores indicated a higher care burden.

    The outcome was assessed at baseline.

  • Perceived social support

    Medical Outcome Study Social Support Survey- Taiwanese version was used to measure the perceived social support for caregivers of stroke survivors. The range of total scores is between 19\~95, and the higher full scores indicated a perception of better social support.

    The outcome was assessed at baseline.

  • Caregivers' quality of life

    Taiwanese version of the World Health Organization Quality of Life BREF(WHOQOL-BREF) was used to measure caregivers' quality of life. The range of total scores is between 4\~20, and the higher full scores indicated a better quality of life. WHOQOL-BREF was used to measure the quality of life of stroke survivors' caregivers.

    The outcome was assessed at baseline.

  • Rehabilitation adherence

    A single item of rehabilitation adherence measurement was used to measure stroke Patients' rehabilitation adherence levels. The range of scores is between 1\~5, and the highest scores indicated an optimal adherence level.

    The outcome was assessed at baseline.

  • Change from baseline depressive symptoms at first month

    Depressive symptoms were measured using the Taiwanese Depression Scale.The range of total scores is between 0\~54, the scores higher than 19 indicated an increased risk of depression.

    The outcome was assessed at first month after inclusion.

  • Change from baseline caregiver care burden at first month

    The caregiver strain index (CSI) was used to measure caregiver care burden. The range of total scores is between 0\~13, the higher total scores indicated a higher care burden.

    The outcome was assessed at first month after inclusion.

  • Change from baseline perceived social support at first month

    Medical Outcome Study Social Support Survey- Taiwanese version was used to measure the perceived social support for caregivers of stroke survivors. The range of total scores is between 19\~95, and the higher full scores indicated a perception of better social support.

    The outcome was assessed at first month after inclusion.

  • Change from baseline caregivers' quality of life at first month

    Taiwanese version of the World Health Organization Quality of Life BREF(WHOQOL-BREF) was used to measure caregivers' quality of life. The range of total scores is between 4\~20, and the higher full scores indicated a better quality of life.WHOQOL-BREF was used to measure the quality of life of stroke survivors' caregivers.

    The outcome was assessed at first month after inclusion.

  • Change from baseline rehabilitation adherence at first month

    A single item of rehabilitation adherence measurement was used to measure stroke patients' rehabilitation adherence levels. The range of scores is between 1\~5, and the highest scores indicated an optimal adherence level.

    The outcome was assessed at first month after inclusion.

  • Change from baseline depressive symptoms at third month

    Depressive symptoms were measured using the Taiwanese Depression Scale.The range of total scores is between 0\~54, the scores higher than 19 indicated an increased risk of depression.

    The outcome was assessed at third after inclusion.

  • Change from baseline caregiver care burden at third month

    The caregiver strain index (CSI) was used to measure caregiver care burden. The range of total scores is between 0\~13, the higher total scores indicated a higher care burden.

    The outcome was assessed at third after inclusion.

  • Change from baseline perceived social support at third month

    Medical Outcome Study Social Support Survey- Taiwanese version was used to measure the perceived social support for caregivers of stroke survivors. The range of total scores is between 19\~95, and the higher full scores indicated a perception of better social support.

    The outcome was assessed at third after inclusion.

  • Change from baseline caregivers' quality of life at third month

    Taiwanese version of the World Health Organization Quality of Life BREF (WHOQOL-BREF) was used to measure caregivers' quality of life. The range of total scores is between 4\~20, and the higher full scores indicated a better quality of life. WHOQOL-BREF was used to measure the quality of life of stroke survivors' caregivers.

    The outcome was assessed at third after inclusion.

  • Change from baseline rehabilitation adherence at third month

    A single item of rehabilitation adherence measurement was used to measure stroke patients' rehabilitation adherence levels. The range of scores is between 1\~5, and the highest scores indicated an optimal adherence level.

    The outcome was assessed at third after inclusion.

Study Arms (2)

Family-centered support program for caregivers of stroke survivors

EXPERIMENTAL

Participants receive usual hospital care and our intervention

Other: Family-centered support program for caregivers of stroke survivors

No Intervention: Control group

NO INTERVENTION

Participants receive only usual hospital care

Interventions

Once participants joined the family-centered support group, participants received 90-minute interventions, including an introduction to stroke and rehabilitation education, problem-solving skills training, and long-term care information. Investigators also invited participants to join the instant messaging application-based 24-h peer-support group for caregivers. On the second and fourth days after receiving the interventions, the researcher visited the participants to review and practice the content provided on the first day; each session was 30 to 40 minutes long. The researcher contacted the participants one week after participants joined the study to discuss their care difficulties or experiences and did so three times biweekly thereafter via the instant messaging application.

Family-centered support program for caregivers of stroke survivors

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Caregivers:
  • Aged 20 years or older
  • Primarily responsible for caring for the stroke survivor in the hospital and after discharge.
  • Stroke survivors:
  • Diagnosed with moderate stroke (National Institute of Health Stroke Scale ≥5 or Modified Rank in Scale ≥3), including ischemic and hemorrhagic stroke, via computed tomography or magnetic resonance imaging within one month. admitted to the stroke unit at a medical center
  • Had a primary family caregiver.

You may not qualify if:

  • Caregivers:
  • Refusal to participate in the study
  • Unable to communicate, for example, non-Chinese speakers
  • Reported having been diagnosed with psychiatric illness (such as major depression) and undergoing treatment.
  • Stroke survivors:
  • Unstable vital signs
  • Terminal illness
  • Transfer to long-term care facilities after hospital discharge
  • Self-reported having been diagnosed with psychiatric illness (such as major depression) and undergoing treatment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Chang Gung University of Science and Technology

Taoyuan District, 33303, Taiwan

Location

MeSH Terms

Conditions

StrokeCaregiver Burden

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesStress, PsychologicalBehavioral SymptomsBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
To prevent contact between participants in the intervention and control groups, we allocated participants from the G ward to the intervention group and those from the H ward to the control group. Participants were not given information about the group allocations.
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Model Details: The family-centered support program included four components: (A) Stroke and rehabilitation education. (B) Problem-solving skills training. (C) Long-term care information support. (D) Instant messaging application-based 24-h peers-support group for caregivers.
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
assistant professor

Study Record Dates

First Submitted

December 13, 2022

First Posted

December 29, 2022

Study Start

August 16, 2021

Primary Completion

October 31, 2022

Study Completion

October 31, 2022

Last Updated

December 29, 2022

Record last verified: 2022-12

Data Sharing

IPD Sharing
Will not share

Locations