NCT05648552|Unknown
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Sponsor study identifier
observational
70
1 country
1
Study Start
January 1, 2022
Actual (reported)Primary Completion
June 30, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
December 31, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
The current study aims to reveal the SC-FC coupling pattern and its relationship with motor function in post-stroke survivors with motor dysfunction by multimodal MRI.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 31, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 1, 2022
Actual (reported)December 5, 2022
Actual (reported)December 13, 2022
Actual (reported)June 30, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
December 31, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Structural-functional Connectivity Coupling
The coupling between structural connectivity and functional connectivity
Within 1 week after enrollment
Fugl-Meyer Assessment
Assessing the motor function in post-stroke participants
Within 1 week after enrollment
Chinese version of Modified Barthel Index
Within 1 week after enrollment
Broetz Hand Test
Within 1 week after enrollment
Placebo Questionnaire
Within 1 week after enrollment
Hamilton Depression Rating Scale
Within 1 week after enrollment
Chinese (Putonghua) Version of Oxford Cognitive Screen
Within 1 week after enrollment
Chronic subcortical stroke participants with motor dysfunction
Well-matched healthy controls
To recruit 35 chronic subcortical post-stroke participants with motor dysfunction and 35 well-matched healthy controls from the Department of Rehabilitation Medicine of Nanjing Drum Tower Hospital and the local communities.
Nanjing Drum Tower Hospital
Nanjing, Jiangsu, 210008, China
Hong W, Wang Y, Zhang X, Wu Y, Liu Z, Zhao G, Xu R, Zhao Z. Motor-related reorganization in left inferior frontal gyrus after subcortical stroke: neurochemical basis and response to targeted neuromodulation. BMC Med. 2026 Mar 27;24(1):297. doi: 10.1186/s12916-026-04810-2.
Hong W, Liu Z, Zhang X, Li M, Yu Z, Wang Y, Wang M, Wu Y, Fang S, Yang B, Xu R, Zhao Z. Distance-related functional reorganization predicts motor outcome in stroke patients. BMC Med. 2024 Jun 18;22(1):247. doi: 10.1186/s12916-024-03435-7.
Wenjun Hong
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
First Submitted
December 5, 2022
First Posted
December 13, 2022
Study Start
January 1, 2022
Actual (reported)Primary Completion
June 30, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study on the Correlation Between Neurotrophic Factors and the Condition of Stroke Patients
Contact the study team to confirm eligibility.
Study Completion
December 31, 2025
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
March 23, 2023
Record last verified: 2023-03
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Source: ClinicalTrials.gov.
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