SALGOT; Stroke Arm Longitudinal Study at the University of GOThenburg

NCT01115348 | Unknown

• 1 other identifier: SALGOT
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Stroke is the most common cause for motor disability in the grown-up population in the Western world. In Sweden \> 80 % are above 65 years of age at onset (1).Areas in the brain, controlling the movement in the upper extremity (UE) are often damaged at a stroke, which leads to impaired function. This impairment of the UE often leads to limitations in activities of daily living and reductions in the level of social activities; therefore, interventions that will improve function are needed to reduce the consequences for the person living with stroke. The time course of recovery of the UE is not clear and therefore the optimal timing of the intervention for the person and its content (ways of intervention) uncertain. The investigators have developed objective assessments of motor performance with new technology (kinematic analysis and virtual reality with haptics). Since having an impaired UE often results in reduced capacity in daily living and social activities, this might lead to decreased participation. To complement the traditional focus on body function, there is a need for assessments of the person's activity level and participation, as well as self-perceived function. The results from this study will lay the ground for an intervention study focusing on improved function in the upper extremity.

Conditions

Stroke; Motor Activity

Outcome Measures

Primary Outcomes (1)

• Upper extremity function

  12 months

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The group consists of consecutively included persons from stroke units (Sahlgrenska University Hospital)

You may qualify if:

• first occurrence of a stroke will be included and followed longitudinally for one year after the stroke.
• Reduced UE function on the M-MAS UAS-95 on day 2 after stroke \> 18 years of age

You may not qualify if:

• Other disease/injury that affect upper extremity function
• Life expectancy less than 12 months (study time)
• Not able to communicate in Swedish
• Not living in the catchment area of the hospital

Sponsors & Collaborators

• Göteborg University: lead

Study Sites (1)

Stroke Unit, Sahlgrenska University Hospital

Gothenburg, Sweden

Location

Related Publications (9)

• Thrane G, Sunnerhagen KS, Murphy MA. Upper limb kinematics during the first year after stroke: the stroke arm longitudinal study at the University of Gothenburg (SALGOT). J Neuroeng Rehabil. 2020 Jun 15;17(1):76. doi: 10.1186/s12984-020-00705-2.

  PMID: 32539738 DERIVED

• Ghaziani E, Couppe C, Siersma V, Christensen H, Magnusson SP, Sunnerhagen KS, Persson HC, Alt Murphy M. Easily Conducted Tests During the First Week Post-stroke Can Aid the Prediction of Arm Functioning at 6 Months. Front Neurol. 2020 Jan 9;10:1371. doi: 10.3389/fneur.2019.01371. eCollection 2019.

  PMID: 31993016 DERIVED

• Hussain N, Sunnerhagen KS, Alt Murphy M. End-point kinematics using virtual reality explaining upper limb impairment and activity capacity in stroke. J Neuroeng Rehabil. 2019 Jul 1;16(1):82. doi: 10.1186/s12984-019-0551-7.

  PMID: 31262320 DERIVED

• Thrane G, Alt Murphy M, Sunnerhagen KS. Recovery of kinematic arm function in well-performing people with subacute stroke: a longitudinal cohort study. J Neuroeng Rehabil. 2018 Jul 18;15(1):67. doi: 10.1186/s12984-018-0409-4.

  PMID: 30021596 DERIVED

• Hussain N, Alt Murphy M, Sunnerhagen KS. Upper Limb Kinematics in Stroke and Healthy Controls Using Target-to-Target Task in Virtual Reality. Front Neurol. 2018 May 9;9:300. doi: 10.3389/fneur.2018.00300. eCollection 2018.

  PMID: 29867717 DERIVED

• Olsson OA, Persson HC, Alt Murphy M, Sunnerhagen KS. Early prediction of physical activity level 1 year after stroke: a longitudinal cohort study. BMJ Open. 2017 Aug 4;7(8):e016369. doi: 10.1136/bmjopen-2017-016369.

  PMID: 28780554 DERIVED

• Persson HC, Danielsson A, Sunnerhagen KS. A cross sectional study of upper extremity strength ten days after a stroke; relationship between patient-reported and objective measures. BMC Neurol. 2015 Oct 1;15:178. doi: 10.1186/s12883-015-0436-8.

  PMID: 26427533 DERIVED

• Persson HC, Alt Murphy M, Danielsson A, Lundgren-Nilsson A, Sunnerhagen KS. A cohort study investigating a simple, early assessment to predict upper extremity function after stroke - a part of the SALGOT study. BMC Neurol. 2015 Jun 18;15:92. doi: 10.1186/s12883-015-0349-6.

  PMID: 26084397 DERIVED

• Alt Murphy M, Persson HC, Danielsson A, Broeren J, Lundgren-Nilsson A, Sunnerhagen KS. SALGOT--Stroke Arm Longitudinal study at the University of Gothenburg, prospective cohort study protocol. BMC Neurol. 2011 May 25;11:56. doi: 10.1186/1471-2377-11-56.

  PMID: 21612620 DERIVED

MeSH Terms

Conditions

Stroke; Motor Activity

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases; Behavior

Study Officials

• Katharina Stibrant Sunnerhagen, MD, PhD

  Göteborg University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 3, 2010
• First Posted: May 4, 2010
• Study Start: March 1, 2009
• Primary Completion: December 1, 2011
• Study Completion: December 1, 2017
• Last Updated: February 2, 2017

Record last verified: 2017-02

Locations

SE (1)