Effect of Precise Grip Strength Training on PICC Catheter-Related Thrombosis in Cancer Patients

NCT05638048 | Completed

• 1 other identifier: YXLL-KY-2022(057)
• Study Type: interventional
• Target: 270
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, color Doppler ultrasound diagnostic instrument and electronic grip device were used to determine the best grip strength of patients with tumor PICC catheterization, formulate precise and standardized grip strength training guidance for them, provide personalized functional exercise health education, and observe the impact of precise grip strength training guidance on Peripheral central venous catheter-associated thrombosis. To provide a reference for clinical prevention of Peripheral central venous catheter-associated thrombosis in the future.

Conditions

Lung Cancer; Stomach Cancer; Breast Cancer; Liver Cancer; Colon Cancer; Rectal Cancer

Keywords

PICC；Cancer patients；Grip strength training

Outcome Measures

Primary Outcomes (1)

• Incidence of Peripheral central venous catheter-associated thrombosis in patients with PICC tube

  Before catheterization, 24 hours after catheterization, and weekly maintenance, color Doppler ultrasound diagnostic instrument was used to diagnose venous thrombosis (including asymptomatic thrombosis) and its classification. The patients were observed for 8 weeks.

  8 weeks

Secondary Outcomes (3)

• Hemodynamic changes of the patient

  8 weeks

• Analysis of the influencing factors of Peripheral central venous catheter-associated thrombosis formation

  8 weeks

• Patients' satisfaction with health education after PICC catheterization

  8 weeks

Study Arms (3)

The control group

ACTIVE COMPARATOR

Patients were routinely implanted with PICC and received routine health education. The content of health education included face-to-face language explanation of the whole process of catheter knowledge, issuing catheter maintenance manual, issuing ordinary grip ball and telling how to use it, and follow-up.

Behavioral: Health education on routine grip strength training

Experiment 1 set

EXPERIMENTAL

Patients were routinely implanted with PICC, and the optimal duration-relaxation time of grip strength training was adopted on the basis of health education in the control group.

Behavioral: Use maximum strength grip training

Experiment 2 set

EXPERIMENTAL

On the basis of control group 1. Determine the best grip strength On the basis of the control group, color Doppler ultrasound and electronic grip force were used to record the optimal grip strength of patients to achieve effective blood flow velocity before and 24 hours after PICC insertion. 2. Design precise grip strength training guidance program On the basis of the control group, the patients were instructed to perform grip strength training according to the determined best grip strength and the best duration of clenching and relaxation time.

Behavioral: Precision grip training

Interventions

Precision grip training BEHAVIORAL

First determine patients for holding the ball movement should reach the effective blood flow velocity and best duration - relaxation, and USES the electronic grips and color doppler ultrasonic diagnostic apparatus, for individual patients to choose the best grip the efforts and training, to form the best grip the training plan, and observe the scheme for Peripheral central venous catheter-associated thrombosis prevention effect.

Experiment 2 set

Use maximum strength grip training BEHAVIORAL

Patients were routinely implanted with PICC, and on the basis of health education in the control group, the best continuous-relaxation time, frequency and maximum grip strength of patients were used for grip strength training.

Experiment 1 set

Health education on routine grip strength training BEHAVIORAL

Patients were routinely implanted with PICC and received routine health education. The content of health education included face-to-face language explanation of the whole process of catheter knowledge, issuing catheter maintenance manual, issuing ordinary grip ball and telling how to use it, and follow-up.

The control group

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Cancer patients undergoing chemotherapy throughout their treatment in our hospital
• Patients with PICC implanted for the first time and maintained at our hospital;
• Age 18-60 years;
• Normal cognitive function;
• the clenching movement is barrier-free;
• The material and performance of PICC catheter are silicone three-way valve catheter;
• Catheter placement under the guidance of portable color Doppler ultrasound diagnostic instrument;
• Voluntarily participate and sign the informed consent form.

You may not qualify if:

• Patients treated with combined radiotherapy;
• Patients with coagulation dysfunction;
• Patients who need to use anticoagulant drugs due to underlying diseases;
• Puncture times more than 1 time;
• The blood flow velocity of catheterization vessel in calm state was less than 4.78cm/s.

Sponsors & Collaborators

• Junyan Zhao: lead

Study Sites (1)

Qianfoshan Hospital

Jinan, Shandong, 250000, China

Location

MeSH Terms

Conditions

Lung Neoplasms; Stomach Neoplasms; Breast Neoplasms; Liver Neoplasms; Colonic Neoplasms; Rectal Neoplasms

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases; Gastrointestinal Neoplasms; Digestive System Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Stomach Diseases; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Liver Diseases; Colorectal Neoplasms; Intestinal Neoplasms; Colonic Diseases; Intestinal Diseases; Rectal Diseases

Study Officials

• Junyan Zhao, Master

  Qianfoshan Hospital

  STUDY DIRECTOR

• Yuanjing Qiao, Master

  Shandong University of Traditional Chinese Medicine

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: August 24, 2022
• First Posted: December 6, 2022
• Study Start: July 10, 2022
• Primary Completion: December 31, 2022
• Study Completion: January 10, 2023
• Last Updated: February 3, 2023

Record last verified: 2023-02

Locations

CN (1)