The Feasibility and Safety of Head-up Cardiopulmonary Resuscitation in Patients With Non-traumatic Cardiac Arrest
1 other identifier
interventional
20
1 country
1
Brief Summary
Head up CPR with impedance threshold device(ITD) and active compression-decompression (ACD) has been proved to improve both cerebral and coronary perfusion pressure during resuscitation in animal models. Increased rates of Spontaneous Circulation (ROSC) were also observed in cardiac arrest patients. The goal of this clinical trial is to learn about the feasibility and safety of Head-up Cardiopulmonary Resuscitation in patients with non-traumatic cardiac arrest. Participants will be received head-up CPR during resuscitation. The main question it aims to answer is if there is any adverse or unfavorable event during resuscitation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Nov 2022
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 19, 2022
CompletedStudy Start
First participant enrolled
November 4, 2022
CompletedFirst Posted
Study publicly available on registry
November 8, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2023
CompletedAugust 9, 2023
August 1, 2023
1.2 years
October 19, 2022
August 8, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Number and portion of participants with serious or non-serious adverse event
e.g. event of fall, failure of intubation
Up to 1 day
Secondary Outcomes (3)
Number and portion of participants with repeated CPR
up to 1 day
Number and portion of participants with survival to emergency department discharge
up to 1 day
Number and portion of participants with sustained return of spontaneous circulation
Up to 1 day
Study Arms (1)
Head-up Cardiopulmonary Resuscitation
EXPERIMENTALInterventions
Elevate patient's head to 30 degrees by EleGARD System during cardiopulmonary resuscitation
Eligibility Criteria
You may qualify if:
- Non-traumatic cardiac arrest
- Age ≥ 20
You may not qualify if:
- Trauma
- Age \< 20
- Pregnancy
- Irreversible death (e.g. liver mortis, rigor mortis, decapitation, transection and decomposition)
- Disorder of cervical spine
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Taiwan University Hospital
Taipei, 100, Taiwan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Wei-Ting Chen
National Taiwan University Hospital
- PRINCIPAL INVESTIGATOR
Chien-Hua Huang
National Taiwan University Hospital
- PRINCIPAL INVESTIGATOR
Min-Shan Tsai
National Taiwan University Hospital
- STUDY CHAIR
Chih-Hsien Lin
National Taiwan University Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 19, 2022
First Posted
November 8, 2022
Study Start
November 4, 2022
Primary Completion
December 31, 2023
Study Completion
December 31, 2023
Last Updated
August 9, 2023
Record last verified: 2023-08
Data Sharing
- IPD Sharing
- Will not share