Pre-shock Cardiopulmonary Resuscitation to Patients With Out-of-hospital Resuscitation, A Randomised Clinical Trial
CPR
Does Longer Pre-shock Cardiopulmonary Resuscitation Improve the Outcome of Patients With Out-of-hospital Cardiac Arrest? A Randomized Control Trial.
2 other identifiers
interventional
1,666
1 country
1
Brief Summary
- 1.Pre-shock cardiopulmonary resuscitation might benefit the survival of out-of-hospital cardiac patients with ventricular fibrillation / ventricular tachycardia in a post-hoc analysis of a prehospital trial conducted in Europe (L.Wik,2002). However, it's effectiveness in the Asian countries, where most firstly recorded rhythm in out-of-hospital cardiac arrests patients were asystole/pulseless electric activity rather than ventricular fibrillation / ventricular tachycardia, were not explored yet.
- 2.This trial was designed to exam if pre-shock cardiopulmonary resuscitation by emergency medical technicians improves the outcome of all out-of-hospital cardiac arrest patients in an Asian metropolitan city.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Feb 2008
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2008
CompletedFirst Submitted
Initial submission to the registry
March 30, 2008
CompletedFirst Posted
Study publicly available on registry
April 2, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2009
CompletedJanuary 5, 2012
December 1, 2011
1.8 years
March 30, 2008
January 2, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Sustained ROSC >= 2 hours
180 days
Secondary Outcomes (3)
surival to ICU admission
180 days
survival to hospital discharge
180 days
Rates of good neurology recovery (CPC 1 &2)
180 days
Study Arms (2)
CPR first
ACTIVE COMPARATORCompression First (CF)
Analysis First
ACTIVE COMPARATORRhythm analysis first
Interventions
10 cycles of 30:2 cardiopulmonary resuscitation before rhythm analysis by AED
Rhythm analysis as soon as AED is ready
Eligibility Criteria
You may qualify if:
- Patients with out-of-hospital cardiac arrest
You may not qualify if:
- Trauma
- Age \< 18y/o
- Airway obstruction
- Submersion
- Sign of obvious death
- existing do not resuscitate (DNAR) order
- family refusal
- preceding CPR by BLS teams for longer than 2 minutes.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Emergency Medicine, National Taiwan University Hospital
Taipei, Taiwan
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Matthew Huei-Ming Ma, MD, PHD
Department of Emergency Medicine, NTUH.
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 30, 2008
First Posted
April 2, 2008
Study Start
February 1, 2008
Primary Completion
December 1, 2009
Study Completion
December 1, 2009
Last Updated
January 5, 2012
Record last verified: 2011-12