Acute Responses of Postural Alignment, Kinematic Synergy, and Intermuscular Coherence to Postural Muscle Facilitation
1 other identifier
interventional
15
1 country
1
Brief Summary
Clinicians frequently assess and intervene on postural alignment. However, research demonstrating the effects of exercise interventions in moving postural alignment toward an evidence-based standard is lacking. Part of the difficulty in establishing such evidence has been a lack of theory-motivated conceptions of what "good" posture is. In other words, the prevailing understanding of postural alignment is based on the negation of what has been observed to associate with bad outcomes. This study will build upon preliminary findings from our laboratory that define good postural alignment on theoretical grounds. The investigators will measure motion capture and muscle activation patterns during simple postural alignment tasks before and after 1) a corrective exercise intervention, or 2) a control intervention based designed to inhibit superficial muscle tension. The corrective exercise intervention is designed to counteract the natural patterns in which the human skeleton tends to collapse from a standing position under the influence of gravity. The control intervention consists of passive, partner-assisted stretching. Regardless of initial assignment, all participants will crossover (i.e. switch interventions) and repeat the study procedures after a 1-week washout period. Behavioral indicators of movement and nervous system coordination will be used to quantify alignment before and after exercise, as well as the consistency of those alignment patterns with theoretically-defined standards. The knowledge gained from this study will contribute to evidence-based definitions of healthy postural alignment and help identify effective interventions by which clinicians can promote good posture.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Oct 2022
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 25, 2022
CompletedFirst Submitted
Initial submission to the registry
October 28, 2022
CompletedFirst Posted
Study publicly available on registry
November 8, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2023
CompletedNovember 8, 2022
November 1, 2022
6 months
October 28, 2022
November 2, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (8)
Euclidean distance from the vector describing subject-specific, simulated gravitational collapse
This outcome is a cumulative descriptor of segment angle distance from the pattern in which an individual's posture would collapse. The reference point for each individual is calculated using both pre and post-intervention data for a given day.
Immediately before Intervention (Day 1)
Euclidean distance from the vector describing subject-specific, simulated gravitational collapse
This outcome is a cumulative descriptor of segment angle distance from the pattern in which an individual's posture would collapse. The reference point for each individual is calculated using both pre and post-intervention data for a given day.
Immediately after Intervention (Day 1)
Euclidean distance from the vector describing subject-specific, simulated gravitational collapse
This outcome is a cumulative descriptor of segment angle distance from the pattern in which an individual's posture would collapse. The reference point for each individual is calculated using both pre and post-intervention data for a given day.
Immediately before Intervention (Day 7)
Euclidean distance from the vector describing subject-specific, simulated gravitational collapse
This outcome is a cumulative descriptor of segment angle distance from the pattern in which an individual's posture would collapse. The reference point for each individual is calculated using both pre and post-intervention data for a given day.
Immediately after Intervention (Day 7)
Pooled intermuscular coherence
Weighted average of frequency-domain correlations between muscle pairs belonging to anterior, posterior, and trunk muscle groups.
Immediately before Intervention (Day 1)
Pooled intermuscular coherence
Weighted average of frequency-domain correlations between muscle pairs belonging to anterior, posterior, and trunk muscle groups.
Immediately after Intervention (Day 1)
Pooled intermuscular coherence
Weighted average of frequency-domain correlations between muscle pairs belonging to anterior, posterior, and trunk muscle groups.
Immediately before Intervention (Day 7)
Pooled intermuscular coherence
Weighted average of frequency-domain correlations between muscle pairs belonging to anterior, posterior, and trunk muscle groups.
Immediately after Intervention (Day 7)
Secondary Outcomes (4)
Top-down kinetic chain continuity
Immediately before Intervention (Day 1)
Top-down kinetic chain continuity
Immediately after Intervention (Day 1)
Top-down kinetic chain continuity
Immediately before Intervention (Day 7)
Top-down kinetic chain continuity
Immediately after Intervention (Day 7)
Study Arms (2)
Exercise Then Stretch
OTHERParticipants in AB will perform the experimental (exercise) intervention first and the control (stretch) intervention second
Stretch Then Exercise
OTHERParticipants in BA will perform the experimental (exercise) intervention second and the control (stretch) intervention first
Interventions
This arm (sequence) will perform an anti-gravity kinetic chain intervention and then a passive, partner-assisted stretching intervention, separated by a one-week washout period.
This arm (sequence) will perform a passive, partner-assisted stretching intervention and then an anti-gravity kinetic chain intervention , separated by a one-week washout period.
Eligibility Criteria
You may qualify if:
- Healthy adult
- years of age
You may not qualify if:
- Recent (\< 6 months) history of lower extremity injury
- Recent (\< 6 months) history of other musculoskeletal or neurological disorder affecting balance
- Contraindications to participation in physical activity
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Radford University Carilion
Roanoke, Virginia, 24013, United States
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
October 28, 2022
First Posted
November 8, 2022
Study Start
October 25, 2022
Primary Completion
May 1, 2023
Study Completion
May 1, 2023
Last Updated
November 8, 2022
Record last verified: 2022-11
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL, SAP, ICF, ANALYTIC CODE
- Time Frame
- On request and indefinitely.
De-identified raw data for individual participants will be shared upon request with parties committing to institutional data sharing agreements.