Multimodal Quantified Analysis of Facial Movements: Comparison Between Pathological and Control Subjects

NCT05581680 | Recruiting

• 1 other identifier: PI2021_843_0207
• Study Type: interventional
• Target: 720
• Locations: 1 country
• Sites: 1

Brief Summary

The facial palsy is a frequent disease with a lot of etiologies. It has variable severities with sometimes heavy functional repercussions and different recovery potentials. The proposed treatments are based on surgery, physiotherapy and botulinum toxin injections. However, when recovery is incomplete, acceptance is more difficult, with an impacted quality of life. Thanks to Motion Capture and Electromyography, a quantification of the facial mimicry is now possible with a great precision. In addition with the quantification of the facial mimicry, eye-tracking, wich is widely used in the marketing field, but it also finds medical applications including head and neck lesions and facial palsy in particular, will be used to evaluate the visio of the patients on their pathology in function of the movement quantification measured with MoCap and Electromyography. The aim of this research is to measure in a combined way the action potentials by sEMG and the amplitudes of displacement of the markers in motion capture, for movements determined in a population of patients presenting a facial pathology, in order to compare them with reference values obtained in healthy subjects. In a second step, the aim will be to study if there is a link between the way the patient looks at his pathology and the results of his management (treatment, rehabilitation) which will be quantitatively evaluated thanks to MoCap and sEMG.

Conditions

Electromyography; Eye-tracking; Facial Palsy

Keywords

facial mimics; motion capture; electromyography; eye-tracking; Facial Palsy

Outcome Measures

Primary Outcomes (4)

• determination of baseline values of facial mimicry (in millimetres) in healthy volunteers

  determination of baseline values of facial mimicry (in millimetres) in healthy volunteers

  one month

• determination of baseline values of eye-tracking (in millimetres) in healthy volunteers

  determination of baseline values of eye-tracking (in millimetres) in healthy volunteers

  one month

• determination of the maximum range of motion of facial mimicry (in millimetres) in patients

  determination of the maximum range of motion facial mimicry (in millimetres) in patients

  one year

• determination of the maximum range of motion of eye-tracking (in millimetres) in patients

  determination of the maximum range of motion of eye-tracking (in millimetres) in patients

  one year

Study Arms (2)

patients with facial palsy

EXPERIMENTAL

Other: dental impressions; Other: Simultaneous MoCap and EMG acquisition; Other: Eye-tracking acquisition for pathological subjects; Other: Follow-up visit for pathological subjects

healthy volunteers

ACTIVE COMPARATOR

Other: dental impressions; Other: Simultaneous MoCap and EMG acquisition

Interventions

dental impressions OTHER

dental impressions

healthy volunteers; patients with facial palsy

Simultaneous MoCap and EMG acquisition OTHER

Simultaneous MoCap and EMG acquisition

healthy volunteers; patients with facial palsy

Eye-tracking acquisition for pathological subjects OTHER

Eye-tracking acquisition for pathological subjects

patients with facial palsy

Follow-up visit for pathological subjects OTHER

Follow-up visit for pathological subjects

patients with facial palsy

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Subjects with no known facial pathology (healthy volunteers) OR
• Patients with peripheral facial palsy, irrespective of grade, whether or not previously treated
• Subject with written informed consent
• Subject over 18 years of age
• Subject affiliated to a social security scheme

You may not qualify if:

• Subjects with severe skin disorders that do not allow the application of electrodes or photo reflective markers
• Subjects with speech disorders making it impossible to pronounce the sounds \[o\] and \[pu\]
• Subject unable to provide written informed consent
• Subjects under guardianship, curators or safeguard of justice

Sponsors & Collaborators

• Centre Hospitalier Universitaire, Amiens: lead

Study Sites (1)

CHU Amiens Picardie

Amiens, Picardie, 80054, France

RECRUITING

MeSH Terms

Conditions

Facial Paralysis

Interventions

Dental Impression Technique

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases; Paralysis; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Technology, Dental; Dentistry

Central Study Contacts

Stéphanie Dakpé, Pr

CONTACT

03 22 08 90 50; dakpe.stephanie@chu-amiens.fr

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 12, 2022
• First Posted: October 14, 2022
• Study Start: October 12, 2022
• Primary Completion (Estimated): October 1, 2027
• Study Completion (Estimated): October 1, 2028
• Last Updated: May 28, 2025

Record last verified: 2025-05

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)