NCT05912751

Brief Summary

Postural alignment is often intervened upon in health, fitness, and physical medicine settings. Despite a long tradition in this area, current notions of optimal or normal posture are superficial and often logically inconsistent. A recent attempt to reconcile diverging opinions about good posture proposes that alignment be considered in relation to individual joints' natural tendencies to collapse under gravity. This theory allows different maladaptive postures to be described in terms of functional deficits and compensatory adaptations at the muscular level. Working within this type of theory, postural interventions may be able to account for comparative advantages in maintaining alignment between different muscle systems. This would represent a step forward from current practices, which usually attempt to force arbitrary alignment patterns indiscriminately. The current study presents motion capture and electromyography (EMG) data evaluating the effects of two interventions on individual participants' bipedal standing alignment patterns with respect to the gravitational collapsing tendencies referenced above. Additional outcomes included functional grouping of muscle activation signals (via intermuscular coherence) and kinetic chain continuity. The interventions include 1) an experimental intervention purported to engage muscles that naturally resist the collapsing effects of gravity, and 2) a control intervention designed to inhibit other muscle groups that are sometimes involved in maintaining bipedal alignment in a compensatory role. Study outcomes are measured before and after both interventions to quantify the acute effects of each. All participants complete both interventions in random order, crossing over after a one-week washout period. This research will provide insight into the acute effects of studied interventions, specifically those relating to maintenance of bipedal alignment with respect to gravitational collapsing tendencies.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Aug 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 10, 2021

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 14, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 14, 2022

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

June 12, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

June 22, 2023

Completed
Last Updated

June 22, 2023

Status Verified

June 1, 2023

Enrollment Period

8 months

First QC Date

June 12, 2023

Last Update Submit

June 12, 2023

Conditions

Outcome Measures

Primary Outcomes (8)

  • Euclidean distance from the vector describing subject-specific, simulated gravitational collapse

    This outcome is a cumulative descriptor of segment angle distance from the pattern in which an individual's posture would collapse. The reference point for each individual is calculated using both pre and post-intervention data for a given day.

    Immediately before Intervention (Day 1)

  • Euclidean distance from the vector describing subject-specific, simulated gravitational collapse

    This outcome is a cumulative descriptor of segment angle distance from the pattern in which an individual's posture would collapse. The reference point for each individual is calculated using both pre and post-intervention data for a given day.

    Immediately after Intervention (Day 1)

  • Euclidean distance from the vector describing subject-specific, simulated gravitational collapse

    This outcome is a cumulative descriptor of segment angle distance from the pattern in which an individual's posture would collapse. The reference point for each individual is calculated using both pre and post-intervention data for a given day.

    Immediately before Intervention (Day 7)

  • Euclidean distance from the vector describing subject-specific, simulated gravitational collapse

    This outcome is a cumulative descriptor of segment angle distance from the pattern in which an individual's posture would collapse. The reference point for each individual is calculated using both pre and post-intervention data for a given day.

    Immediately after Intervention (Day 7)

  • Pooled intermuscular coherence

    Weighted average of frequency-domain correlations between muscle pairs belonging to anterior, posterior, and trunk muscle groups.

    Immediately before Intervention (Day 1)

  • Pooled intermuscular coherence

    Weighted average of frequency-domain correlations between muscle pairs belonging to anterior, posterior, and trunk muscle groups.

    Immediately after Intervention (Day 1)

  • Pooled intermuscular coherence

    Weighted average of frequency-domain correlations between muscle pairs belonging to anterior, posterior, and trunk muscle groups.

    Immediately before Intervention (Day 7)

  • Pooled intermuscular coherence

    Weighted average of frequency-domain correlations between muscle pairs belonging to anterior, posterior, and trunk muscle groups.

    Immediately after Intervention (Day 7)

Secondary Outcomes (4)

  • Top-down kinetic chain continuity

    Immediately before Intervention (Day 1)

  • Top-down kinetic chain continuity

    Immediately after Intervention (Day 1)

  • Top-down kinetic chain continuity

    Immediately before Intervention (Day 7)

  • Top-down kinetic chain continuity

    Immediately after Intervention (Day 7)

Study Arms (2)

Exercise Then Foam Roll

OTHER

This arm (sequence) will first complete the exercise intervention promoting muscular engagement resisting gravitational collapsing tendencies, then the control intervention involving self-myofascial release of muscle groups not thought to resist gravitational collapse.

Other: Exercise Then Foam Roll

Foam Roll Then Exercise

OTHER

This arm (sequence) will first complete the control intervention involving self-myofascial release of muscle groups not thought to resist gravitational collapse, then the exercise intervention promoting muscular engagement resisting gravitational collapsing tendencies.

Other: Foam Roll Then Exercise

Interventions

Participants in AB will perform the experimental (exercise) intervention first and the control (foam rolling) intervention second.

Also known as: AB
Exercise Then Foam Roll

Participants in BA will perform the control (foam rolling) intervention first and the experimental (exercise) intervention second.

Also known as: BA
Foam Roll Then Exercise

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Healthy adult
  • years of age

You may not qualify if:

  • Recent (\< 6 months) history of lower extremity injury
  • Recent (\< 6 months) history of other musculoskeletal or neurological disorder affecting balance
  • Contraindications to participation in physical activity

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Radford University Carilion

Roanoke, Virginia, 24013, United States

Location

Study Officials

  • Stephen Glass, PhD

    Radford University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

June 12, 2023

First Posted

June 22, 2023

Study Start

August 10, 2021

Primary Completion

April 14, 2022

Study Completion

April 14, 2022

Last Updated

June 22, 2023

Record last verified: 2023-06

Data Sharing

IPD Sharing
Will share

De-identified raw data for individual participants will be shared upon request with parties committing to institutional data sharing agreements.

Shared Documents
STUDY PROTOCOL, SAP, ICF, ANALYTIC CODE
Time Frame
On request and indefinitely.

Locations