Motivations to Transplant Registry Participation

NCT05595382 | Completed Results

• 1 other identifier: Pro2022000536
• Study Type: interventional
• Target: 397
• Locations: 1 country
• Sites: 1

Brief Summary

The current study seeks to understand factors that influence college students' likelihood of participating the National Marrow Donor Program (NMDP)/Be the Match for bone marrow and stem cell donations. The secondary aim is to compare emotional and rational approaches to encouraging participation in the registry and how these approaches may impact intentions to participate in the NMDP.

Conditions

Healthy

Keywords

stem cell transplant; bone marrow donor; motivations; altruism

Outcome Measures

Primary Outcomes (1)

• Intention to Register

  Participants rated the likelihood of registering on a 1-7 scale with higher scores indicating greater intention to join the registry (better outcome). Participants were asked these questions before (baseline) and after (post-intervention) the experimental manipulation.

  Baseline and after the experimental manipulation (Post-Intervention)

Secondary Outcomes (2)

• Mood

  Baseline and after experimental manipulation (Post-Intervention)

• Psychosocial and Demographic Correlates of Intentions to Register--Knowledge

  Baseline

Study Arms (2)

Emotional Group

EXPERIMENTAL

Participants will be randomly assigned to receive an emotional or rational appeal, stratified by sex.

Behavioral: Emotional Appeal

Rational Group

EXPERIMENTAL

Participants will be randomly assigned to receive an emotional or rational appeal, stratified by sex.

Behavioral: Rational Appeal

Interventions

Emotional Appeal BEHAVIORAL

Participants will be presented with a short vignette about a child undergoing cancer treatment and needing a bone marrow transplant in order to survive cancer.

Emotional Group

Rational Appeal BEHAVIORAL

Participants will be presented with data regarding the importance of considering race/ethnicity when looking for a bone marrow transplant donor and the likelihood of finding a match based on the patient's racial/ethnic background.

Rational Group

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Rutgers Camden Students enrolled in Psych 101 and Method and Theory
• Between the ages of 18-35

You may not qualify if:

• Students under 18 years of age or over 36 or older will be excluded.

Sponsors & Collaborators

• Rutgers, The State University of New Jersey: lead

Study Sites (1)

Rutgers University Camden

Camden, New Jersey, 08102, United States

Location

Related Publications (18)

• Billen A, Madrigal JA, Scior K, Shaw BE, Strydom A. Donation of peripheral blood stem cells to unrelated strangers: A thematic analysis. PLoS One. 2017 Oct 25;12(10):e0186438. doi: 10.1371/journal.pone.0186438. eCollection 2017.

  PMID: 29069088 BACKGROUND

• Butterworth VA, Simmons RG, Bartsch G, Randall B, Schimmel M, Stroncek DF. Psychosocial effects of unrelated bone marrow donation: experiences of the National Marrow Donor Program. Blood. 1993 Apr 1;81(7):1947-59.

  PMID: 8461479 BACKGROUND

• CROWNE DP, MARLOWE D. A new scale of social desirability independent of psychopathology. J Consult Psychol. 1960 Aug;24:349-54. doi: 10.1037/h0047358. No abstract available.

  PMID: 13813058 BACKGROUND

• Fingrut W, Parmar S, Cuperfain A, Rikhraj K, Charman E, Ptak E, Kahlon M, Graham A, Luong S, Wang YG, Yu J, Arora N, Suppiah R, Li EW, Lee A, Welsh C, Benzaquen M, Thatcher A, Baharmand I, Ladd A, Petraszko T, Allan D, Messner H. The Stem Cell Club: a model for unrelated stem cell donor recruitment. Transfusion. 2017 Dec;57(12):2928-2936. doi: 10.1111/trf.14327. Epub 2017 Sep 24.

  PMID: 28944484 BACKGROUND

• Gardner, Paul. (1987). Measuring ambivalence to science. Journal of Research in Science Teaching. 24. 241 - 247. 10.1002/tea.3660240305.

  BACKGROUND

• Kaster EC, Rogers CR, Jeon KC, Rosen B. Getting to the Heart of Being the Match: A Qualitative Analysis of Bone Marrow Donor Recruitment and Retention Among College Students. Health Educ (Muncie). 2014 Spring;46(1):14-19.

  PMID: 25632376 BACKGROUND

• Monaghan M, Yi QL, Green M, Campbell T, Weiss JT, Dibdin N, Mercer D, Elmoazzen H, Allan DS. Factors associated with registrant availability for unrelated adult donor hematopoietic stem cell donation: Analysis of the stem cell registry at Canadian Blood Services. Transfusion. 2021 Jan;61(1):24-28. doi: 10.1111/trf.16129. Epub 2020 Oct 21.

  PMID: 33084098 BACKGROUND

• Narayanan P, Wolanskyj A, Ehlers SL, Litzow MR, Patnaik MS, Hogan WJ, Hashmi SK. Medical Students' Knowledge, Familiarity, and Attitudes towards Hematopoietic Stem Cell Donation: Stem Cell Donation Behaviors. Biol Blood Marrow Transplant. 2016 Sep;22(9):1710-1716. doi: 10.1016/j.bbmt.2016.06.014. Epub 2016 Jun 22.

  PMID: 27343721 BACKGROUND

• National Marrow Donor Program (2013). Key Figures and Facts. www.bethematch.com

  BACKGROUND

• Onitilo AA, Lin YH, Okonofua EC, Afrin LB, Ariail J, Tilley BC. Race, education, and knowledge of bone marrow registry: indicators of willingness to donate bone marrow among African Americans and Caucasians. Transplant Proc. 2004 Dec;36(10):3212-9. doi: 10.1016/j.transproceed.2004.10.019.

  PMID: 15686731 BACKGROUND

• Rose A, Peters N, Shea JA, Armstrong K. Development and testing of the health care system distrust scale. J Gen Intern Med. 2004 Jan;19(1):57-63. doi: 10.1111/j.1525-1497.2004.21146.x.

  PMID: 14748861 BACKGROUND

• Rosenberg, M. (1965). Rosenberg self-esteem scale. Journal of Religion and Health.

  BACKGROUND

• Rushton, J. P., Chrisjohn, R. D., & Fekken, G. C. (1981). The altruistic personality and the self-report altruism scale. Personality and individual differences, 2(4), 293-302.

  BACKGROUND

• Surana, P. K., & Lomas, T. (2014). The power of charity: Does giving away money improve the wellbeing of the donor. Indian Journal of Positive Psychology, 5(3), 223-230.

  BACKGROUND

• Studts JL, Ruberg JL, McGuffin SA, Roetzer LM. Decisions to register for the National Marrow Donor Program: rational vs emotional appeals. Bone Marrow Transplant. 2010 Mar;45(3):422-8. doi: 10.1038/bmt.2009.174. Epub 2009 Aug 3.

  PMID: 19648972 BACKGROUND

• Vasconcellos A, Nunes A, Feller E. Knowledge, attitudes, and behaviors regarding the bone marrow registry among college and medical students in Rhode Island. Med Health R I. 2011 Oct;94(10):302-5. No abstract available.

  PMID: 22164662 BACKGROUND

• Vekaria KM, Hammell AE, Vincent L, Smith M, Rogers T, Switzer GE, Marsh AA. The role of prospection in altruistic bone marrow donation decisions. Health Psychol. 2020 Apr;39(4):316-324. doi: 10.1037/hea0000819. Epub 2019 Nov 14.

  PMID: 31724423 BACKGROUND

• Daniel LC, Elias G, Shah P, Kokolis N. Increasing participation in the national marrow donor program: A randomized trial. J Health Psychol. 2025 Sep 28:13591053251367869. doi: 10.1177/13591053251367869. Online ahead of print.

  PMID: 41015944 DERIVED

MeSH Terms

Conditions

Altruism

Condition Hierarchy (Ancestors)

Social Behavior; Behavior

Results Point of Contact

• Title: Dr. Lauren Daniel
• Organization: Rutgers University Associate Professor

lauren.daniel@rutgers.edu

856-225-6535

Study Officials

• Lauren C Daniel, Ph.D.

  Rutgers University

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: September 15, 2022
• First Posted: October 27, 2022
• Study Start: October 10, 2022
• Primary Completion: November 6, 2023
• Study Completion: November 6, 2023
• Last Updated: April 18, 2025
• Results First Posted: April 18, 2025

Record last verified: 2025-04

Locations

US (1)