Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation

NCT05586308 | Completed Results

• 2 other identifiers: 0596-22-EPU54GM115458
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the feasibility and compare the preliminary effect of vaping cessation program consisting of media literacy education and real-time text messaging support and leverage insights from behavioral economics to enhance social and financial incentives to improve program engagement, and eventually abstinence. Our hypotheses are that 1) the Combined arm is associated with improved vaping abstinence to the Media literacy and Financial incentive arms; and 2) the financial incentive-related arms (either Combined or Financial incentive) enhance engagement compared to the non-incentive related arms.

Conditions

Behavior, Health Risk; Implementation Science; E Cigarette Use; Cessation, Smoking; Incentives; Engagement, Patient; Peer Support; Media Literacy

Outcome Measures

Primary Outcomes (2)

• Engagement_remote checkin_3

  Engagement will be assessed by proportions of participants who submitted the remote saliva cotinine sample at remote checkin 3.

  3 months

• Retention

  The number of participants who completed the end-of-study assessment (Week 12).

  3 months

Secondary Outcomes (2)

• Biochemically Verified Vaping Abstinence

  3 months

• Self-reported Vaping Abstinence

  3 months

Study Arms (4)

Active control

OTHER

Participants in this arm will receive an evidence-based text-messaging support.

Behavioral: Text-massaging suport

Media literacy

ACTIVE COMPARATOR

Participants will receive media literacy e-learning lessons and an evidence-based text-messaging support.

Behavioral: Text-massaging suport; Behavioral: Media literacy

Financial incentive

ACTIVE COMPARATOR

Participants will receive financial incentive intervention and an evidence-based text-messaging support.

Behavioral: Text-massaging suport; Behavioral: Financial incentive

Combined

EXPERIMENTAL

Participants will receive media literacy e-learning lessons, financial incentive, and an evidence-based text-messaging support program.

Behavioral: Text-massaging suport; Behavioral: Financial incentive; Behavioral: Media literacy

Interventions

Text-massaging suport BEHAVIORAL

Text-messaging quitting support program (i.e., This is Quitting) is an evidence-based, free mobile program from Truth Initiative designed to help young people quit vaping. The program is fully automated and interactive. To establish or reinforce perceived social norms and social support around quitting, a majority of messages come from other users who have submitted them to the program.

Active control; Combined; Financial incentive; Media literacy

Financial incentive BEHAVIORAL

1. Participants will earn $3 for each saliva cotinine sample submission regardless of positive or negative results after the quit day (an assessments at Week 6, Week 8, Week 10, and Week 12, during the abstinence phase) 2. Participants will earn additional escalating rewards for each negative sample- $7 for Week 6, $12 for Week 8, $17 for Week 10, and $22 for Week 12 (2 months after the target quit date). The bonus starts at $7 and increase by $5 for each subsequent negative cotinine sample (i.e., $7, $12, $17, and $22). 3. A reset contingency will be used. That is the reward amount will be returned back to original $7 if there is a missing or positive saliva cotinine sample

Combined; Financial incentive

Media literacy BEHAVIORAL

Media literacy e-learning lessons cover topics regarding what e-cigarettes are and how they work, how nicotine and nicotine addiction affects the brain and behavior, how to prepare to quit vaping, developing a quit plan and how to deal with cravings and relapse. The program focuses on changing knowledge, attitudes and beliefs related to e-cigarette use, as well as emphasizing vaping related media literacy.

Combined; Media literacy

Eligibility Criteria

• Age: 19 Years - 29 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Aged 19-29
• Report vaping in the previous 30 days
• Have access to internet/video chat/SMS text message
• Are interested in quitting vaping in the next 30 days

You may not qualify if:

• Self-report as currently pregnant or planning to become pregnant in the next 3 months
• Already involved in vaping cession programs (either behavioral or medical intervention)

Sponsors & Collaborators

• University of Nebraska: lead
• National Institute of General Medical Sciences (NIGMS): collaborator

Study Sites (1)

Unversity of Nebraska Medical Center

Omaha, Nebraska, 68198, United States

Location

Related Publications (1)

• Michaud T, Puga T, Archer R, Theye E, Zagurski C, Estabrooks P, Dai HD. Enhancing Text Message Support With Media Literacy and Financial Incentives for Vaping Cessation in Young Adults: Protocol for a Pilot Randomized Controlled Trial. JMIR Res Protoc. 2025 Feb 21;14:e60527. doi: 10.2196/60527.

  PMID: 39983103 DERIVED

MeSH Terms

Conditions

Health Risk Behaviors; Vaping; Smoking Cessation; Patient Participation

Condition Hierarchy (Ancestors)

Health Behavior; Behavior; Smoking; Patient Acceptance of Health Care; Treatment Adherence and Compliance

Results Point of Contact

• Title: Tzeyu Michaud
• Organization: University of Nebraska Medical Center

tzeyu.michaud@unmc.edu

4028369195

Study Officials

• Tzeyu Michaud, PhD

  University of Nebraska

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: This study employs a pilot, 4-arm randomized clinical trial design.

Study Record Dates

• First Submitted: October 14, 2022
• First Posted: October 19, 2022
• Study Start: December 7, 2023
• Primary Completion: November 1, 2024
• Study Completion: June 30, 2025
• Last Updated: January 29, 2026
• Results First Posted: January 29, 2026

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will share
• Shared Documents: SAP, ICF, CSR
• Time Frame: Data requests can be submitted starting 12 months after article publication and the data will be made accessible for up to 24 months. Extensions will be considered on a case-by-case basis
• Access Criteria: Access to trial IPD can be requested by qualified researchers engaging in independent scientific research, and will be provided following review and approval of a research proposal and Statistical Analysis Plan (SAP) and execution of a Data Sharing/USE Agreement.

Locations

US (1)