NCT06196489

Brief Summary

The objective of this proposal is to adapt an evidence-based combustible tobacco counseling intervention following an evidence-based process to include e-cigarette use and update its components for emerging adults (EA).

  1. 1.Examine factors related to e-cigarette use, barriers to cessation, and facilitators of use of cessation services among an EA population.
  2. 2.Beta-test an initial version of the intervention, delivered via video telehealth and telephone, to examine usability and acceptability.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
0mo left

Started Jan 2024

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress97%
Jan 2024Jun 2026

First Submitted

Initial submission to the registry

December 13, 2023

Completed
19 days until next milestone

Study Start

First participant enrolled

January 1, 2024

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 9, 2024

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2026

Last Updated

January 8, 2026

Status Verified

September 1, 2025

Enrollment Period

2.4 years

First QC Date

December 13, 2023

Last Update Submit

January 6, 2026

Conditions

E Cigarette Use

Keywords

Veterane-cigarettevapingyoung adult

Outcome Measures

Primary Outcomes (3)

  • e-cigarette use frequency

    number of days using e-cigarettes in the past 7 days at the time of assessment

    end of treatment (8 weeks post-baseline) and 30 days thereafter

  • e-cigarette use quantity

    number of e-cigarette uses per day

    end of treatment (8 weeks post-baseline) and 30 days thereafter

  • Client Satisfaction Questionnaire (CSQ-8)

    Participant satisfaction ratings; higher scores indicate greater satisfaction with the intervention

    end of treatment (8 weeks post-baseline) and 30 days thereafter

Study Arms (2)

telephone

EXPERIMENTAL

Participants assigned to this group will receive the adapted intervention by telephone.

Behavioral: adapted vaping cessation intervention

Video

EXPERIMENTAL

Participants assigned to this group will receive the adapted intervention by video telehealth.

Behavioral: adapted vaping cessation intervention

Interventions

adapted vaping cessation interventionBEHAVIORAL

Behavioral intervention for vaping cessation

Videotelephone

Eligibility Criteria

Age18 Years - 30 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • daily e-cigarette user for at least the past 6 months
  • years old
  • willing to enroll in a program to quit nicotine use within 30 days
  • owns smartphone or computer/tablet with camera and internet connectivity
  • English speaker

You may not qualify if:

  • ICD-10 diagnosis of dementia
  • current use of combustible tobacco products at least weekly

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Veterans Medical Research Foundation

San Diego, California, 92161, United States

RECRUITING

Related Publications (6)

  • Palmer AM, Tomko RL, Squeglia LM, Gray KM, Carpenter MJ, Smith TT, Dahne J, Toll BA, McClure EA. A pilot feasibility study of a behavioral intervention for nicotine vaping cessation among young adults delivered via telehealth. Drug Alcohol Depend. 2022 Mar 1;232:109311. doi: 10.1016/j.drugalcdep.2022.109311. Epub 2022 Jan 19.

    PMID: 35123362BACKGROUND

  • Kinouani S, Leflot C, Vanderkam P, Auriacombe M, Langlois E, Tzourio C. Motivations for using electronic cigarettes in young adults: A systematic review. Subst Abus. 2020;41(3):315-322. doi: 10.1080/08897077.2019.1671937. Epub 2019 Oct 22.

    PMID: 31638872BACKGROUND

  • Harrell PT, Brandon TH, Stark SE, Simmons VN, Barnett TE, Quinn GP, Chun S. Measuring vaping-related expectancies in young adults: Psychometric evaluation of the Electronic Nicotine Vaping Outcomes (ENVO) scale. Drug Alcohol Depend. 2023 May 1;246:109861. doi: 10.1016/j.drugalcdep.2023.109861. Epub 2023 Mar 29.

    PMID: 37028105BACKGROUND

  • Cuccia AF, Patel M, Amato MS, Stephens DK, Yoon SN, Vallone DM. Quitting e-cigarettes: Quit attempts and quit intentions among youth and young adults. Prev Med Rep. 2021 Jan 5;21:101287. doi: 10.1016/j.pmedr.2020.101287. eCollection 2021 Mar.

    PMID: 33489721BACKGROUND

  • Buu A, Hu YH, Wong SW, Lin HC. Comparing American college and noncollege young adults on e-cigarette use patterns including polysubstance use and reasons for using e-cigarettes. J Am Coll Health. 2020 Aug-Sep;68(6):610-616. doi: 10.1080/07448481.2019.1583662. Epub 2019 Mar 25.

    PMID: 30908151BACKGROUND

  • Bandi P, Star J, Minihan AK, Patel M, Nargis N, Jemal A. Changes in E-Cigarette Use Among U.S. Adults, 2019-2021. Am J Prev Med. 2023 Aug;65(2):322-326. doi: 10.1016/j.amepre.2023.02.026. Epub 2023 Apr 18.

    PMID: 37479423BACKGROUND

MeSH Terms

Conditions

Vaping

Condition Hierarchy (Ancestors)

SmokingBehavior

Study Officials

  • Neal M Doran, PhD

    Veterans Medical Research Foundation

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Neal M Doran, PhD

CONTACT

858-552-8585neal.doran@va.gov

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 13, 2023

First Posted

January 9, 2024

Study Start

January 1, 2024

Primary Completion (Estimated)

June 1, 2026

Study Completion (Estimated)

June 1, 2026

Last Updated

January 8, 2026

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Sample size is sufficiently small that sharing could threaten confidentiality.

Locations

US(1)