Impact of Financial Incentives

NCT05744960 | Active Not Recruiting

• 2 other identifiers: IMPACTP2FI1P01CA250989-01A1
• Study Type: interventional
• Target: 34
• Locations: 1 country
• Sites: 1

Brief Summary

This trial will look at the impact of clinic-level financial incentives to improve provider communication and increase HPV vaccine uptake. Some clinics will receive communication training. Other clinics will receive the same training and a clinic-level financial incentive program with a monthly data feedback report to increase HPV vaccine uptake.

Conditions

Human Papilloma Virus

Keywords

financial incentives; pediatric medicine; vaccination; pay-for-performance

Outcome Measures

Primary Outcomes (1)

• HPV vaccination (≥1 dose), 9-12 year olds

  Proportion of unvaccinated children who initiate the HPV vaccine series between baseline and 12-month follow-up, among those who were ages 9-12 at baseline.

  from baseline to 12 months

Secondary Outcomes (3)

• HPV vaccination (≥1 dose), 9-12 year olds

  from 13 months to 24 months

• HPV vaccination (≥2 doses), 9-12 year olds

  from baseline to 12 months

• HPV vaccination (≥2 doses), 9-12 year olds

  from 13 months to 24 months

Study Arms (2)

HPV vaccine communication training.

EXPERIMENTAL

Staff in clinics randomized to this arm will receive an intervention called Announcement Approach Training (AAT). This training is designed to improve communication about HPV vaccination.

Behavioral: Communication training

HPV vaccine communication training and clinic-level financial incentive program

EXPERIMENTAL

Staff in clinics randomized to this arm will receive the Announcement Approach Training and a clinic-level financial incentive program with a monthly data feedback report to increase HPV vaccine uptake.

Behavioral: Communication training; Behavioral: financial Incentive

Interventions

Communication training BEHAVIORAL

Clinics will host an Announcement Approach Training (AAT) workshop. A trained facilitator will use a standard script and slides to deliver workshop in-person or over Zoom; clinical staff who are unavailable will take the workshop later on their own.

HPV vaccine communication training and clinic-level financial incentive program; HPV vaccine communication training.

financial Incentive BEHAVIORAL

Clinics will host an AAT workshop, as in the other trial arm. Clinics in the intervention arm will then receive a 12-month clinic-level financial incentive program with predetermined targets for HPV vaccine initiation rates (5%, 10%, and 30% increases from baseline). Clinics will be notified of their HPV vaccination rates though a monthly, automated report. Clinic achievement will be assessed and incentives will be paid out to clinics monthly. Incentives will be tiered based on target and sized based on the number of clinic providers. For reaching the highest tier of 30%, clinics will receive an aggregate of $1000 per provider.

HPV vaccine communication training and clinic-level financial incentive program

Eligibility Criteria

• Age: 9 Years - 12 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Clinics are eligible if they are a pediatric or family medicine clinic in North Carolina that in the past year had:
• less than 72% HPV vaccine initiation rate,
• greater than or equal to 50 patients ages 9-12
• greater than or equal to 2 HPV vaccine providers
• no clinic or provider-level financial incentive programs to increase system, clinic, or provider HPV vaccination rates among patients aged 9-12 in the past two years, and
• no HPV vaccine provider communication trainings in the past six months.
• Children's medical records will be eligible to be included in the dataset if children:
• are between the ages of 9-12 years at baseline and
• are attributed to a participating clinic at 12- or 24-month follow-up.

You may not qualify if:

• Clinics are excluded if they:
• do not provide HPV vaccine to children ages 9-12
• have a specialty other than pediatrics or family medicine
• had an HPV vaccine-specific financial incentive program in the past two years
• had a formal HPV vaccine communication training in the past 6 months
• had an HPV initiation rate greater than 72$
• had fewer than 49 patients aged 9-12
• had 1 or fewer HPV vaccine providers
• Children's medical records will not be eligible to be included in the dataset if children:
• are not between the ages of 9-12 years at baseline
• are not attributed to a participating clinic at 12- or 24-month follow-up

Sponsors & Collaborators

• National Cancer Institute (NCI): collaborator
• UNC Lineberger Comprehensive Cancer Center: lead

Study Sites (1)

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27599-7590, United States

Location

Study Officials

• Justin G Trogdon, PhD

  University of North Carolina, Chapel Hill

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Cluster randomized design in which clinics will be randomized within healthcare systems

Study Record Dates

• First Submitted: February 15, 2023
• First Posted: February 27, 2023
• Study Start: February 28, 2023
• Primary Completion: April 30, 2026
• Study Completion (Estimated): August 29, 2026
• Last Updated: January 6, 2026

Record last verified: 2026-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)