Effect of Low-level Laser Therapy on Orthodontic Tooth Movement

NCT05550168 | Completed

• 1 other identifier: NearEastU-001
• Study Type: interventional
• Target: 20
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of this trial is to investigate the effect of low-level laser therapy (LLLT) on orthodontic tooth movement during maxillary molar distalization over 12-week observation period.

Conditions

Low Level Laser Therapy

Keywords

Accelerated orthodontic tooth movement; Biostimulation; Molar distalization; Humans

Outcome Measures

Primary Outcomes (1)

• Amount of maxillary molar distalization

  Measurements were made using miniscrew as a reference point. Digital measurements were made on Geomagic Studio 2014 software to evaluate the amount of maxillary molar distalization. All 3D digital model measurements were coded, and the same researcher carried out two separate measurements 1-week apart to increase the reliability of the measurements. Parallelism was ensured between the dental arch and the Y-axis on the side where the measurements would be made by guiding the models. The parallelism of the dental arch to the Y-axis was also assessed from the lateral view. The midpoint of the first miniscrew and the mesial edge of the maxillary first molar were marked in the occlusal view. Then the distance between the projections of these two reference points to the Y-axis was measured. The difference between the two consecutive measurements indicated the 3-week amount of distalization in T1, T2, T3 and T4. This procedure was applied on both sides of all 3D models

  84 days after

Study Arms (3)

Intervention (Laser group)

EXPERIMENTAL

The participants in the intervention group experienced a total of 7 session laser applications on their randomly determined molar region during the 12-week clinical trial period.

Device: Low Level Laser therapy

Contralateral (Non-laser group)

NO INTERVENTION

Laser was not applied to the contralateral side of the intervention group (n=10) and the individuals in the control group (n=10); thus, no application was made to accelerate tooth movement

Control (Non-laser group)

NO INTERVENTION

Laser was not applied to the contralateral side of the intervention group (n=10) and the individuals in the control group (n=10); thus, no application was made to accelerate tooth movement

Interventions

Low Level Laser therapy DEVICE

The participants in the intervention group experienced a total of 7 session laser applications on their randomly determined molar region during the 12-week clinical trial period.

Intervention (Laser group)

Eligibility Criteria

• Age: 16 Years - 22 Years
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Skeletal class I or mild class II malocclusion,
• No untreated decayed teeth,
• Normodivergent skeletal pattern,
• Fully erupted maxillary first and second molars,
• Male and female individuals between the ages of 16 and 22,
• Extracted or congenitally missing maxillary third molars,
• Non smoker,
• No alveolar bone loss or periodontal disease,
• Bilateral class II molar relationship,
• Absence of crowding or spacing in the posterior region,
• Adequate oral hygiene.
• No drug usage that may have an impact on the biology of tooth movement (Example; Non-steroidal anti-inflammatory drugs- NSAIDS)

You may not qualify if:

• Hypodivergent or hyperdivergent skeletal pattern,
• Alveolar bone loss or periodontal disease,
• Systemic illnesses that might affect bone metabolism,
• Any drug use that may have an impact on the biology of tooth movement (Example; Non-steroidal anti-inflammatory drugs- NSAIDS),
• Inadequate oral hygiene,
• Unilateral class II molar relationship,
• Smoker,
• Severe class II skeletal malocclusion (ANB\>7°),
• Crowding or spacing in the posterior region,
• Missing maxillary second molars,
• Existence of maxillary third molars,
• Having untreated decayed teeth.

Sponsors & Collaborators

• Near East University, Turkey: lead

Study Sites (1)

Beren Özsoy

Nicosia, Cyprus

Location

Related Publications (1)

• Ozsoy B, Gulduren K, Kamiloglu B. Effect of low-level laser therapy on orthodontic tooth movement during miniscrew-supported maxillary molar distalization in humans: a single-blind, randomized controlled clinical trial. Lasers Med Sci. 2023 Feb 20;38(1):76. doi: 10.1007/s10103-023-03736-y.

  PMID: 36807215 DERIVED

MeSH Terms

Interventions

Low-Level Light Therapy

Intervention Hierarchy (Ancestors)

Laser Therapy; Therapeutics; Phototherapy

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: DMD, Research assistant

Model Details: A clinical trial with experimental and control groups

Study Record Dates

• First Submitted: September 15, 2022
• First Posted: September 22, 2022
• Study Start: January 29, 2021
• Primary Completion: September 1, 2021
• Study Completion: January 14, 2022
• Last Updated: September 22, 2022

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will not share

Locations

CY (1)