Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD
1 other identifier
observational
92
1 country
1
Brief Summary
INTRODUCTION: Relationship between comorbidities and COPD is two-sided. While the number of comorbidities increasing, the frequency of acute exacerbations of COPD (AECOPD) is increasing, too. Comorbidity indexes can be used for recognition of comorbidities while managing COPD patients. In the present study, it is aimed to compare comorbidity indexes such as Charlson Comorbidity Index, COMCOLD and COTE in the matter of exacerbation frequency. METHOD: Subjects hospitalized for AECOPD, admitted to the study. Exacerbation severity, frequency, further exacerbations for a 1-year period in the follow-up period and CCI, COMCOLD and COTE scores were recorded. High and low comorbidity groups were compared for AECOPD frequency, severity, and further exacerbations.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2018
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2022
CompletedFirst Submitted
Initial submission to the registry
August 14, 2022
CompletedFirst Posted
Study publicly available on registry
August 17, 2022
CompletedAugust 17, 2022
August 1, 2022
6 months
August 14, 2022
August 16, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Frequency of AECOPD
Frequency of AECOPD in the last one year
1 year
Secondary Outcomes (2)
Having at least one severe AECOPD
1 year
Frequency of AECOPD for the next one year
1 year
Study Arms (2)
High comorbidity group
CCI equal or higher than 2 COTE equal or higher than 4 COMCOLD equal or higher than 4
Low comorbidity group
CCI lower than 2 COTE lower than 4 COMCOLD lower than 4
Interventions
No intervention has been applied. 92 COPD patients divided into 2 groups according to their comorbidity level. Than these groups were compared for their AECOPD frequency
Eligibility Criteria
The study included all patients, admitted to pulmonary diseases department, and hospitalized in ward for acute exacerbation of COPD (AECOPD) for a six-month period.
You may qualify if:
- COPD patients
- Admitted to the ward for AECOPD
You may not qualify if:
- Not giving informed consent
- Unable to perform PFT
- Lost to follow-up
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Ankara University Faculty of Medicine
Ankara, Turkey (Türkiye)
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- University Lecturer
Study Record Dates
First Submitted
August 14, 2022
First Posted
August 17, 2022
Study Start
January 1, 2018
Primary Completion
July 1, 2018
Study Completion
January 1, 2022
Last Updated
August 17, 2022
Record last verified: 2022-08