Effects of Chair-Based Exercise Training on Exercise Capacity in Patients With Acute Exacerbation of COPD

NCT05563493 | Completed

• 1 other identifier: 1
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality worldwide, a respiratory disease characterized by chronic airflow limitation that is not completely reversible. Impaired pulmonary functions, decreased exercise capacity and quality of life and increased dyspnea perception is prevalent in patients with acute exacerbations of COPD.It was demonstrated exercise training has beneficial effects in patients with acute exacerbations of COPD. The purpose of this study to evaluate the effects of chair-based exercise training on exercise capacity, respiratory functions, dyspnea, balance, depression anxiety and quality of life in COPD patients in acute exacerbation.

Conditions

Acute Exacerbation of COPD

Keywords

Chair-based exercise training

Outcome Measures

Primary Outcomes (2)

• Functional Exercise Capacity

  Functional exercise capacity will be evaluated with 6-minute walk test.

  Seven day

• Pulmonary Function Test

  This test was evaluated using a spirometry by which is evaluated dynamic lung functions expressed as percentages of expected values.

  Seven day

Secondary Outcomes (5)

• Dyspnea

  Seven day

• One Minute Sit to Stand Test

  Seven day

• Timed Up and Go Test

  Seven day

• Depression and Anxiety

  Seven day

• Life of quality

  Seven day

Study Arms (2)

Treatment group, Chair-Based Exercise Training

EXPERIMENTAL

Treatment group will receive chair-based exercise training. Chair-based exercise training consisting of 20 different exercises will be applied in 2-3 sets with an average of 8-15 repetitions. Rest between sets will average 45-60 seconds.

Other: Treatment group, Chair-Based Exercise Training

Control group, Breathing exercise

OTHER

Control group will receive breathing exercises.

Other: Control group, Breathing exercise

Interventions

Treatment group, Chair-Based Exercise Training OTHER

The weights of the elastic bands to be used in the exercises will be determined by the physiotherapist according to the abilities and development of the participants. The intensity of the exercise will be adjusted according to the dyspnea or fatigue patients feel according to the Modified Borg Scale. During the exercises, heart rate and oxygen saturation will be measured with a pulse oximeter, and blood pressure will be measured with a sphygmomanometer. Chair-based exercise training will be applied to the patients every day they are hospitalized.

Treatment group, Chair-Based Exercise Training

Control group, Breathing exercise OTHER

Breathing exercise will be applied to the patients every day they are hospitalized.

Control group, Breathing exercise

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients who were hospitalized due to acute exacerbation of COPD

You may not qualify if:

• Patients with orthopedic or neurological problems that may interfere with assessment and education,
• Uncooperative patients,
• Patients with advanced heart problems such as acute coronary syndrome, stable angina pectoris, severe arrhythmias (Atrial fibrillation etc.), decompensated heart failure.

Sponsors & Collaborators

• Necmettin Erbakan University: lead

Study Sites (1)

Necmettin Erbakan University Nezahat Keleşoğlu Faculty of Health Sciences

Konya, 42090, Turkey (Türkiye)

Location

Related Publications (4)

• Liao S, Wang F, Lin Q, Jian F, Li Y, Zhong Q, Huang Y, Lin Y, Wang H. Effect of sitting and lying Liuzijue exercise for pulmonary rehabilitation in acute exacerbation of chronic obstructive pulmonary disease patients with non-invasive ventilation: a randomized controlled trial. Ann Palliat Med. 2021 Sep;10(9):9914-9926. doi: 10.21037/apm-21-2157.

  PMID: 34628916 BACKGROUND

• Knaut C, Bonfanti Mesquita C, Dourado VZ, de Godoy I, Tanni SE. Evaluation of Inflammatory Markers in Patients Undergoing a Short-Term Aerobic Exercise Program while Hospitalized due to Acute Exacerbation of COPD. Int J Inflam. 2020 Apr 28;2020:6492720. doi: 10.1155/2020/6492720. eCollection 2020.

  PMID: 32411343 BACKGROUND

• Burtin C, Decramer M, Gosselink R, Janssens W, Troosters T. Rehabilitation and acute exacerbations. Eur Respir J. 2011 Sep;38(3):702-12. doi: 10.1183/09031936.00079111. Epub 2011 Jun 30.

  PMID: 21719481 BACKGROUND

• Kon SS, Canavan JL, Man WD. Pulmonary rehabilitation and acute exacerbations of COPD. Expert Rev Respir Med. 2012 Nov;6(5):523-31; quiz 531. doi: 10.1586/ers.12.47.

  PMID: 23134247 BACKGROUND

MeSH Terms

Interventions

Control Groups; Breathing Exercises

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods; Mind-Body Therapies; Complementary Therapies; Therapeutics; Exercise Movement Techniques; Physical Therapy Modalities

Study Officials

• Zeynep Pelin DÜNDAR, MSc,PT

  Necmettin Erbakan University

  PRINCIPAL INVESTIGATOR

• Nihan KAFA

  Gazi University

  STUDY DIRECTOR

• Hülya VATANSEV

  Necmettin Erbakan University

  STUDY DIRECTOR

• Neslihan DURUTÜRK

  Baskent University

  STUDY CHAIR

• Adil ZAMANİ

  Necmettin Erbakan University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant

Study Record Dates

• First Submitted: September 26, 2022
• First Posted: October 3, 2022
• Study Start: August 20, 2022
• Primary Completion: May 31, 2023
• Study Completion: June 30, 2023
• Last Updated: February 7, 2024

Record last verified: 2022-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)