NCT05470959

Brief Summary

compare 2-year clinical performance of recent bioactive ionic resin composite to resin-modified glass ionomer liner in indirect dental pulp treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2019

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 10, 2019

Completed
2.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 30, 2021

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 20, 2021

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

July 19, 2022

Completed
3 days until next milestone

First Posted

Study publicly available on registry

July 22, 2022

Completed
Last Updated

July 22, 2022

Status Verified

July 1, 2022

Enrollment Period

2.1 years

First QC Date

July 19, 2022

Last Update Submit

July 20, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • assess clinical performance of bioactive ionic resin composite and resin-modified glass ionomer liner by using FDI clinical criteria

    comparison of 2-year clinical performance of recent bioactive ionic resin composite( ACTIVA bioactive) to resin-modified glass ionomer liner ( Riva LC) in indirect dental pulp treatment using FDI world dental federation clinical criteria.

    2-years

Study Arms (2)

ACTIVA bioactive

OTHER

bioactive ionic resin composite

Other: ACTIVA bioactive

Riva LC

OTHER

Resin-modifed glass ionomer

Other: Riva LC

Interventions

bioactive ionic resin composite

ACTIVA bioactive
Riva LCOTHER

resin-modified glass ionomer

Also known as: Riva light cure
Riva LC

Eligibility Criteria

Age20 Years - 50 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • presence of two deep carious lesions, one on each side of the mouth (ICDAS 5 or 6)
  • vital teeth
  • no sensitivity to teeth percussion
  • no spontaneous pain
  • no radiolucency in the periapical or furcation area of teeth
  • complete and normal occlusion
  • good oral hygiene

You may not qualify if:

  • poor oral hygiene
  • severe or chronic periodontal problems
  • periapical lesions
  • heavy bruxism
  • non-vital teeth
  • visibly cracked teeth
  • spontaneous dental pain
  • sensitivity to teeth percussion

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Dentistry

Al Mansurah, 35111, Egypt

Location

Related Publications (1)

  • Ahmed B, Wafaie RA, Hamama HH, Mahmoud SH. 3-year randomized clinical trial to evaluate the performance of posterior composite restorations lined with ion-releasing materials. Sci Rep. 2024 Feb 28;14(1):4942. doi: 10.1038/s41598-024-55329-6.

MeSH Terms

Conditions

Dental Caries

Condition Hierarchy (Ancestors)

Tooth DemineralizationTooth DiseasesStomatognathic Diseases

Study Officials

  • salah mahmoud, professor

    faculty of dentistry, mansoura university

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 19, 2022

First Posted

July 22, 2022

Study Start

October 10, 2019

Primary Completion

October 30, 2021

Study Completion

December 20, 2021

Last Updated

July 22, 2022

Record last verified: 2022-07

Data Sharing

IPD Sharing
Will not share

Locations