Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP
REEPP-WSC
1 other identifier
interventional
24
1 country
1
Brief Summary
This research is conducted to compare the remineralization efficacy of eggshell powder gel and CPP-ACP (MI paste) on post-orthodontic white spot lesions.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Oct 2019
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 15, 2019
CompletedFirst Posted
Study publicly available on registry
May 28, 2019
CompletedStudy Start
First participant enrolled
October 5, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 5, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2020
CompletedMay 28, 2019
May 1, 2019
6 months
May 15, 2019
May 22, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
white spot lesion progression.
The change in the lesion fluorescence will be evaluated using diode laser fluorescence device (Diagnodent).
6 months.
Study Arms (2)
Eggshell powder gel
EXPERIMENTALprepared from eggshell powder. applied on the tooth surfaces twice daily (after breakfast and before bedtime) after brushing the teeth.
CPP-ACP crème
ACTIVE COMPARATORCPP-ACP crème (GC Tooth Mousse). applied on the tooth surfaces twice daily (after breakfast and before bedtime) after brushing the teeth.
Interventions
Eggshell powder gel produced from chicken eggs.
A water-based, sugar-free topical cream containing Recaladent (CCP-ACP) which is derived from the milk protein.
Eligibility Criteria
You may qualify if:
- A patient who has just completed a comprehensive orthodontic treatment.
- Presence of at least one WSL, DIAGNOdent score (0-20).
- Age range between 13 and 35years.
You may not qualify if:
- Patients are unable to return for recall appointments.
- High caries risk.
- Have plaque accumulation and a periodontal problem
- In progress treatment of chronic disease.
- Presence of abnormal oral, medical, or mental condition (including any milk-related allergies or any medical condition involving kidneys or salivary glands).
- Presence of dentin caries, enamel hypoplasia or restorations on maxillary anterior teeth.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Cairo univercity
Cairo, 002, Egypt
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
May 15, 2019
First Posted
May 28, 2019
Study Start
October 5, 2019
Primary Completion
April 5, 2020
Study Completion
June 1, 2020
Last Updated
May 28, 2019
Record last verified: 2019-05