The Relationship Between Breastfeeding During Early Pregnancy and Miscarriage

NCT05461963 | Completed

• 1 other identifier: SiirtUN
• Study Type: observational
• Target: 76
• Locations: 1 country
• Sites: 1

Brief Summary

Breastfeeding provides various health and psychological benefits to mothers and their babies. It also acts as an effective method of natural contraception when applied strictly for up to six months after birth. Studies show that breastfeeding times are getting longer in the USA and more babies are breastfed for more than 12 months compared to the past. Recent research shows that 57% of US infants are breastfed until at least six months of age, and more than a third continue to be breastfed for up to 12 months. Prolonged breastfeeding durations increase the prevalence of breastfeeding during pregnancy, especially with the shortening of the intervals between pregnancies. Breastfeeding during pregnancy is a relatively common practice in many parts of the world. According to the data of studies conducted in low- and middle-income countries, it has been determined that 35% of the last born babies continue to be breastfed in the next pregnancy of their mothers. It has also been shown that the prevalence of breastfeeding during pregnancy in low-income countries is between 15% and 50%. Few research has been done on the relationship between breastfeeding during pregnancy and maternal, infant, or pregnancy outcomes. Some studies have suggested that hormonal mechanisms in pregnancy may link breastfeeding during pregnancy and abortion. When babies stimulate the nipple and areola during sucking, they trigger the release of oxytocin in the mother, causing a series of reactions that push the milk towards the nipple. We know that the prevalence of short and long breastfeeding intervals in pregnancy is high in our country. Therefore, in this study, we are planning to investigate whether there is a relationship between breastfeeding during pregnancy and miscarriage based on this information.

Conditions

Miscarriage; Breast Feeding

Outcome Measures

Primary Outcomes (1)

• Miscarriage, ratio in breastfeeding pregnant women

  Miscarriage is the spontaneous loss of a pregnancy before the 20th week,

  From the 6th week of pregnancy to the 20th week.

Study Arms (2)

breastfeeding pregnants( n:76)

pregnants in early weeks of pregnancy who practice breastfeeding

control group ( n:76)

pregnants in early weeks of pregnancy who not practice breastfeeding

Eligibility Criteria

• Age: 18 Years+
• Sex: female
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Pregnant women over the age of 18 who are in the first trimester of pregnancy and continue to breastfeed

You may qualify if:

• being breastfeeding
• being at the 1.st trimester of pregnancy

You may not qualify if:

• history of inherited thrombophilia
• history of uterine anomaly
• history of trauma
• history of genetic anomaly
• history of habitual abortus

Sponsors & Collaborators

• Siirt University: lead

Study Sites (1)

Siirt Üniversity Medical Faculty

Siirt, 56000, Turkey (Türkiye)

Location

Related Publications (3)

• Molitoris J. Breast-feeding During Pregnancy and the Risk of Miscarriage. Perspect Sex Reprod Health. 2019 Sep;51(3):153-163. doi: 10.1363/psrh.12120. Epub 2019 Sep 16.

  PMID: 31524957 BACKGROUND

• Lopez-Fernandez G, Barrios M, Goberna-Tricas J, Gomez-Benito J. Breastfeeding during pregnancy: A systematic review. Women Birth. 2017 Dec;30(6):e292-e300. doi: 10.1016/j.wombi.2017.05.008. Epub 2017 Jun 19.

  PMID: 28642112 BACKGROUND

• Ayrim A, Gunduz S, Akcal B, Kafali H. Breastfeeding throughout pregnancy in Turkish women. Breastfeed Med. 2014 Apr;9(3):157-60. doi: 10.1089/bfm.2013.0086. Epub 2013 Oct 25.

  PMID: 24160359 BACKGROUND

MeSH Terms

Conditions

Abortion, Spontaneous; Breast Feeding

Condition Hierarchy (Ancestors)

Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Feeding Behavior; Behavior

Study Officials

• Şerif Aksin

  Siirt University Medical Faculty Obstetrics and Gynecology Departmant

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: associate professor

Study Record Dates

• First Submitted: June 26, 2022
• First Posted: July 18, 2022
• Study Start: June 26, 2022
• Primary Completion: January 1, 2023
• Study Completion: January 1, 2023
• Last Updated: January 4, 2023

Record last verified: 2023-01

Locations

TU (1)