NCT05441657

Brief Summary

There is a lack of data of spontaneous breathing patients with post-COVID-19 syndrome (PCS) examined by Electrical impedance tomography (EIT). We compare 100 patients with PCS with 50 healthy probands.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 14, 2022

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

June 29, 2022

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 1, 2022

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 19, 2023

Completed
2.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 28, 2025

Completed
Last Updated

September 25, 2025

Status Verified

September 1, 2025

Enrollment Period

1 year

First QC Date

June 29, 2022

Last Update Submit

September 22, 2025

Conditions

Ventilatory DefectCOVID-19Post-acute COVID-19 SyndromeElectric Impedance TomographyPost-COVID-19 Syndrome

Keywords

post-acute COVID-19 syndromeEITElectric impedance tomographielong-COVIDpost-COVID-19 Syndrome (PCS)

Outcome Measures

Primary Outcomes (1)

  • pathogenic changes in regional lung ventilation

    pathogenic changes in regional lung ventilation considered

    until July 2022

Study Arms (2)

dyspnoeic patients with post-acute COVID-19 syndrome

100 patients with/without persisting dyspnea after COVID-19 disease were examined by Electric Impedance Tomography (EIT).

control group

50 healthy volunteers with no lung disease were voluntarily examined by Electric Impedance Tomography.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

100 patients with postacute COVID-19 syndrome who present themselves at the outpatient clinic of the University hospital in Jena (JUH) were examined by EIT. 50 lunghealthy volunteers were examined by EIT at JUH.

You may qualify if:

  • for control group: no current lung diseases, over 18 years old
  • for patients with postacute COVID-19 syndrome: over 18 years, positive SARS-CoV-2-PCR

You may not qualify if:

  • heart pacemaker
  • epilepsy
  • BMI over 50

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jena university hospital

Jena, Thuringia, 07747, Germany

Location

MeSH Terms

Conditions

COVID-19Post-Acute COVID-19 Syndrome

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract DiseasesPost-Infectious DisordersChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Jan-Christoph Lewejohann, Dr.med.

    Jena University Hospital

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Investigator

Study Record Dates

First Submitted

June 29, 2022

First Posted

July 1, 2022

Study Start

April 14, 2022

Primary Completion

April 19, 2023

Study Completion

August 28, 2025

Last Updated

September 25, 2025

Record last verified: 2025-09

Locations

DE(1)