Risk Factors of Venous Thromboembolism After Incisional Ventral Hernia Repair.

NCT05439187 | Completed

• 1 other identifier: 140-14/22
• Study Type: observational
• Target: 240
• Locations: 1 country
• Sites: 1

Brief Summary

Aim of our study is to find frequency and risk factors for venous thromboembolism development in patients who underwent surgery for incisional ventral hernia. There were 240 patients enrolled in our retrospective observational cohort study. Included patients were operated for incisional hernia in Saveljev University Surgery Clinic from January 2018 to December 2019. Compression duplex ultrasound of lower legs veins was performed in 2-4 days after surgery for all participants. The primary endpoint was the occurrence of the venous thromboembolism event, including pulmonary embolism.

Conditions

Incisional Hernia; Venous Thromboembolism

Keywords

hernia repair; thromboprophylaxis

Outcome Measures

Primary Outcomes (1)

• venous thromboembolism

  Screening ultrasound in the postoperative period was aimed at looking for signs of deep vein thrombosis. The imaged vessels included the common femoral, great saphenous, superficial femoral, deep femoral, popliteal, posterior tibial, and peroneal veins of both lower extremities. The presence of a thrombotic process in the vein was evidenced by the rigidity of its walls during compression by the sensor, the presence of hyperechoic inclusions, and the impossibility of visualizing blood flow during color mapping.

  was performed with median 3 days (min 1 day, max 7 days, interquartile range 2-4 days) after surgery

Interventions

hernia repair PROCEDURE

Open or laparoscopic hernia repair with mesh placement.

Also known as: thromboprophylaxis

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients of Saveljev University Surgery Clinic, Moscow

Sponsors & Collaborators

• Pirogov Russian National Research Medical University: lead

Study Sites (1)

Pirogov Russian National Research Medical University

Moscow, 117997, Russia

Location

MeSH Terms

Conditions

Incisional Hernia; Venous Thromboembolism

Interventions

Herniorrhaphy

Condition Hierarchy (Ancestors)

Hernia; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Postoperative Complications; Pathologic Processes; Thromboembolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Plastic Surgery Procedures; Surgical Procedures, Operative

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: May 23, 2022
• First Posted: June 30, 2022
• Study Start: January 1, 2018
• Primary Completion: December 31, 2019
• Study Completion: January 31, 2020
• Last Updated: June 30, 2022

Record last verified: 2022-06

Locations

RU (1)