Risk Factors of Venous Thromboembolism After Colorectal Cancer Surgery

NCT06302179 | Completed

• 1 other identifier: 140-14/24
• Study Type: observational
• Target: 137
• Locations: 1 country
• Sites: 1

Brief Summary

Aim of our study is to find frequency and identify risk factors for venous thromboembolism development in patients who underwent surgery for colorectal cancer. There were 137 patients enrolled in our retrospective observational cohort study. Included patients were operated for incisional hernia in Saveljev University Surgery Clinic from January 2016 to December 2017. Compression duplex ultrasound of lower legs veins was performed in 2-14 days after surgery for all participants. The primary endpoint was the occurrence of the venous thromboembolism event, including pulmonary embolism.

Conditions

Colorectal Cancer; Venous Thromboembolism

Keywords

colorectal cancer surgery; thromboprophylaxis

Outcome Measures

Primary Outcomes (1)

• Venous Thromboembolism

  Screening ultrasound in the postoperative period was aimed at looking for signs of deep vein thrombosis. The imaged vessels included the common femoral, great saphenous, superficial femoral, deep femoral, popliteal, posterior tibial, and peroneal veins of both lower extremities. The presence of a thrombotic process in the vein was evidenced by the rigidity of its walls during compression by the sensor, the presence of hyperechoic inclusions, and the impossibility of visualizing blood flow during color mapping.

  was performed with median 4 days (min 2 day, max 14 days, interquartile range 2-5 days) after surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Sponsors & Collaborators

• Pirogov Russian National Research Medical University: lead

Study Sites (1)

Pirogov Russian National Research Medical University

Moscow, 117997, Russia

Location

MeSH Terms

Conditions

Colorectal Neoplasms; Venous Thromboembolism

Condition Hierarchy (Ancestors)

Intestinal Neoplasms; Gastrointestinal Neoplasms; Digestive System Neoplasms; Neoplasms by Site; Neoplasms; Digestive System Diseases; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Rectal Diseases; Thromboembolism; Embolism and Thrombosis; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 4, 2024
• First Posted: March 8, 2024
• Study Start: January 1, 2015
• Primary Completion: December 1, 2017
• Study Completion: May 1, 2023
• Last Updated: March 8, 2024

Record last verified: 2024-03

Locations

RU (1)