NCT02928146

Brief Summary

The aim of the study is to evaluate the effectiveness of various methods of inguinal hernia repair and to evaluate techniques of synthetic mesh fixation during laparoscopic and open hernia repair.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2017

Typical duration for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 6, 2016

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 10, 2016

Completed
3 months until next milestone

Study Start

First participant enrolled

January 1, 2017

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2018

Completed
1.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
Last Updated

October 10, 2016

Status Verified

October 1, 2016

Enrollment Period

1.4 years

First QC Date

October 6, 2016

Last Update Submit

October 6, 2016

Conditions

Keywords

TAPPTEPLichtensteinsyntethic meshhernioplasty

Outcome Measures

Primary Outcomes (1)

  • Post-operative complications associated with wound

    Wound infection with or without the need to remove the mesh, Wound necrosis, Hematoma or seroma in the wound.

    30 days after surgery

Secondary Outcomes (1)

  • The frequency of conversions (from laparoscopic to open approach)

    1 year

Other Outcomes (2)

  • Evaluation of the severity of pain according to VAS (visual analogue scale)

    1 year after surgery

  • Quality of life.

    Prior to surgery, 1 and 6 months after the operation using SF-36 questionnaire.

Study Arms (3)

Lichtenstein technique

ACTIVE COMPARATOR

Lichtenstein inguinal hernia repair

Procedure: Hernia Repair

TAPP

ACTIVE COMPARATOR

Transabdominal preperitoneal (TAPP) approach for inguinal hernia repair

Procedure: Hernia Repair

TEP

ACTIVE COMPARATOR

Totally extraperitoneal (TEP) approach for inguinal hernia repair

Procedure: Hernia Repair

Interventions

Hernia RepairPROCEDURE
Lichtenstein techniqueTAPPTEP

Eligibility Criteria

Age18 Years - 65 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • male
  • age: 18 - 65
  • planned inguinal hernia repair using synthetic implant
  • BMI range: 20-35 kg / m2
  • written informed consent

You may not qualify if:

  • prior midline laparotomy
  • contraindications for general anaesthesia
  • ASA \> IV
  • cirrhosis (Child B or C) or ascites
  • active treatment with use of chemiotherapy
  • incarcerated hernia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Hernia, Inguinal

Interventions

Herniorrhaphy

Condition Hierarchy (Ancestors)

Hernia, AbdominalHerniaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Plastic Surgery ProceduresSurgical Procedures, Operative

Study Officials

  • Miroslaw Szura, MD, PhD

    Department of Experimental and Clinical Surgery, Jagiellonian University Medical College

    STUDY DIRECTOR
  • Rafal Solecki, MD, PhD

    Department of Experimental and Clinical Surgery, Jagiellonian University Medical College

    PRINCIPAL INVESTIGATOR
  • Artur Pasternak, MD,PhD

    Department of Anatomy, Jagiellonian University Medical College

    PRINCIPAL INVESTIGATOR
  • Jakub Łomnicki, MD

    Stefan Zeromski Hospital in Krakow

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Miroslaw Szura, MD, PhD

CONTACT

Artur Pasternak, MD, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

October 6, 2016

First Posted

October 10, 2016

Study Start

January 1, 2017

Primary Completion

June 1, 2018

Study Completion

December 1, 2019

Last Updated

October 10, 2016

Record last verified: 2016-10