Assesment of Two Different Modalities of Maxillary Canine Retraction Assisted With Injectable Platelet Rich Fibrin
1 other identifier
interventional
18
1 country
1
Brief Summary
The present prospective clinical study will be undertaken for assessment of two different modalities of maxillary canine retraction assisted with injectable platelet rich fibrin.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_1
Started Nov 2022
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 19, 2022
CompletedFirst Posted
Study publicly available on registry
June 23, 2022
CompletedStudy Start
First participant enrolled
November 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2023
CompletedNovember 14, 2022
November 1, 2022
4 months
June 19, 2022
November 9, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
assessment of acceleration of canine retraction
rate of canine retraction
post interventional at 4 months
Study Arms (2)
Group I
ACTIVE COMPARATORwill include 9 patients
Group II
ACTIVE COMPARATORwill include 9 patients.
Interventions
i-PRF with maxillary canine retraction that will be performed two times on intervention sides according to a standardized protocol.
Eligibility Criteria
You may qualify if:
- An age range from 15-22 years.
- Severe crowding or protrusion requiring 1st premolars extractions followed by symmetrical canine retraction.
- All permanent teeth present, 3rd molars are excluded.
- Good oral and general health.
- No systemic disease/medication that could interfere with OTM. No previous orthodontic treatment.
You may not qualify if:
- Patient diagnosed to have an indication for non-extraction approach.
- Poor oral hygiene or periodontally compromised patient.
- Patient with craniofacial anomalies or previous history of trauma, bruxism or parafunctions.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
AlAzhar university
Cairo, Egypt
Related Publications (2)
Zeitounlouian TS, Zeno KG, Brad BA, Haddad RA. Effect of injectable platelet-rich fibrin (i-PRF) in accelerating orthodontic tooth movement : A randomized split-mouth-controlled trial. J Orofac Orthop. 2021 Jul;82(4):268-277. doi: 10.1007/s00056-020-00275-x. Epub 2021 Jan 22.
PMID: 33481053BACKGROUNDErdur EA, Karakasli K, Oncu E, Ozturk B, Hakki S. Effect of injectable platelet-rich fibrin (i-PRF) on the rate of tooth movement. Angle Orthod. 2021 May 1;91(3):285-292. doi: 10.2319/060320-508.1.
PMID: 33459765BACKGROUND
Study Officials
- PRINCIPAL INVESTIGATOR
mohamed radwan, student
Al-Azhar University
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- BASIC SCIENCE
- Intervention Model
- FACTORIAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
June 19, 2022
First Posted
June 23, 2022
Study Start
November 1, 2022
Primary Completion
March 1, 2023
Study Completion
August 1, 2023
Last Updated
November 14, 2022
Record last verified: 2022-11
Data Sharing
- IPD Sharing
- Will not share