Using of Injectable Platelet Rich Fibrin on Filling the Gap of Immediate Dental Implant

NCT04298294 | Completed

• 1 other identifier: Bassant Mohye
• Study Type: interventional
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

The effect of using of i-PRF (injectable platelet rich fibrin) on filling the gap of immediate dental implant in the esthetic zone

Conditions

Bone Loss

Outcome Measures

Primary Outcomes (3)

• Radiograhic evaluation of the effect of i-PRF on filling the buccal gap distance between the immediately placed dental implant and the surrounding bone.

  density, vertical and horizontal assessment of labial plate

  6 months follow up

• Radiographic analysis

  vertical assessment of labial plate

  6 months follow up

• Radiographic analysis

  density of labial plate

  6 months follow up

Secondary Outcomes (1)

• Esthetic evaluation of the effect of i-PRF on the soft tissue around immediately placed dental implant

  6 months follow up

Study Arms (2)

injectable platelet rich fibrin group

EXPERIMENTAL

8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with i-PRF\& bone graft

Other: injectable platelet rich fibrin

no injectable platelet rich fibrin group

NO INTERVENTION

8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with bone graft

Interventions

injectable platelet rich fibrin OTHER

biologic activator

injectable platelet rich fibrin group

Eligibility Criteria

• Age: 20 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Healthy adult patient.
• Age from 20-50 years old
• Patients must be free of any systemic disease which could influence the surgical procedure.
• Tooth involved in the esthetic zone.
• Sufficient hard and soft tissue volume in vertical and buccolingual 6. Natural teeth adjacent to the involved tooth were required to be free from infection.
• Controlled oral hygiene.
• Indication for tooth extraction included;
• Endodontic failures
• Untreatable caries\> Non- restorable teeth
• Vertical root fracture
• Remaining roots
• The decision to proceed with the implant placement was made after tooth extraction and probing of the extraction socket which revealed:
• The presence of intact facial bone.
• Compliance with all requirements in the study and signing the informed consent.

You may not qualify if:

• Patient had surgeries in the same site during the last 6 months prior to the surgery.
• Severe vertical bone loss (socket type lll or type lV).
• Presence of acute dento-alveolar infection or periodontal affected of involved tooth.
• Pregnant and lactating females.
• Smokers.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Bassant Mohye

Cairo, 11724, Egypt

Location

MeSH Terms

Conditions

Bone Diseases, Metabolic

Condition Hierarchy (Ancestors)

Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Masking Details: double blinded
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Group I (study group)8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with i-PRF\& bone graft Group II (control group) 8 patients undergo flapless single immediate implant placement surgery with filling the gap distance with bone graft

Study Record Dates

• First Submitted: February 29, 2020
• First Posted: March 6, 2020
• Study Start: February 16, 2018
• Primary Completion: October 1, 2019
• Study Completion: December 1, 2019
• Last Updated: March 6, 2020

Record last verified: 2020-03

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)