Demineralized Whole-tooth vs Demineralized Particulate Dentin Grafts in Alveolar Ridge Preservation
1 other identifier
interventional
20
1 country
1
Brief Summary
The aim of this trial is to compare whole-tooth vs particulate dentin for their effects in alveolar ridge preservation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jun 2022
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 4, 2022
CompletedFirst Posted
Study publicly available on registry
April 20, 2022
CompletedStudy Start
First participant enrolled
June 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2023
CompletedApril 20, 2022
April 1, 2022
7 months
April 4, 2022
April 15, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Alveolar bone width change in mm
Alveolar bone linear width will be measured at baseline at final cone beam computed tomography (CBCT) scans. The change in bone width will be calculated as the subtraction of final width from baseline width and will be expressed in millimetres.
6 months
Secondary Outcomes (2)
Alveolar bone height change in mm
6 months
Histological assessment
6 months
Study Arms (2)
Whole-tooth dentin graft
EXPERIMENTALThe extracted tooth will be prepared as whole-tooth dentin graft and inserted in the extraction socket.
Particulate dentin graft
ACTIVE COMPARATORThe extracted tooth will be prepared as particulate dentin graft and inserted in the extraction socket.
Interventions
Minimally-traumatic extraction of non-restorable teeth then grafting with whole-tooth dentin graft
Minimally-traumatic extraction of non-restorable teeth then grafting with particulate dentin graft
Eligibility Criteria
You may qualify if:
- Non-restorable tooth indicated for extraction
- single-rooted teeth
- Patients at least 18 years or older
- Motivated patients, agree to sign informed consent and complete the follow-up period
You may not qualify if:
- Pregnant females
- active infection at extraction site
- Smokers
- systemic conditions affecting healing (e.g. diabetes, medications as bisphosphonates...)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Cairo University
Cairo, Egypt
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal investigator
Study Record Dates
First Submitted
April 4, 2022
First Posted
April 20, 2022
Study Start
June 1, 2022
Primary Completion
January 1, 2023
Study Completion
June 1, 2023
Last Updated
April 20, 2022
Record last verified: 2022-04