AS-OCT Evaluation of Iridocorneal Angle of Patients of Angle Closure Glaucoma After Phacoemulsification

NCT05332665 | Unknown

• 1 other identifier: AS-OCT in ACG
• Study Type: observational
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

Evaluation of the effect of phacoemulsification and YAG Laser peripheral iridotomy on the anterior chamber angle anatomic parameters in PACG eyes, using anterior segment optical coherence tomography (SS ASOCT) device

Conditions

Glaucoma, Angle-Closure

Outcome Measures

Primary Outcomes (1)

• IOP

  mmhg

  up to 6 months

Secondary Outcomes (1)

• Corneal endothelial count

  up to 6 months

Study Arms (3)

Angle opening distance (AOD)

The AOD measured as perpendicular distance between anterior iris surface and point at trabecular meshwork at 500 μm anterior to the scleral spur

Device: AS-OCT; Procedure: YAG laser PI

Trabecular iris space area (TISA) 500

TISA 500 was measured as an area bounded anteriorly by the AOD 500, posteriorly by a line drawn from the scleral spur perpendicular to the plane of the inner scleral wall to the opposing iris, superiorly by the inner corneoscleral wall, and inferiorly by the iris surface

Device: AS-OCT; Procedure: YAG laser PI

Anterior chamber depth (ACD)

The ACD was measured as the perpendicular distance from the corneal endothelium at the corneal apex to the anterior lens surface

Device: AS-OCT; Procedure: YAG laser PI

Interventions

AS-OCT DEVICE

Anterior segment optical coherence tomography (AS OCT) is an imaging device that can acquire an anterior segment image using a noncontact method with the patient in a sitting position. This device provides reproducible and quantitative measurements of the AC angle and other anterior segment parameters.

Angle opening distance (AOD); Anterior chamber depth (ACD); Trabecular iris space area (TISA) 500

YAG laser PI PROCEDURE

medical procedure which uses a laser device to create a hole in the iris, thereby allowing aqueous humor to traverse directly from the posterior to the anterior chamber and, consequently, relieve a pupillary block

Angle opening distance (AOD); Anterior chamber depth (ACD); Trabecular iris space area (TISA) 500

Eligibility Criteria

• Age: 30 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Patients with acute attack of ACG with phacoemulsification in this eye with YAG laser PI in the other eye

You may qualify if:

• patients with acute attack of angle closure glaucoma in one eye.
• Patients fit for phacoemulsification

You may not qualify if:

• Patients with history of any intraocular surgery. 2- Patients with history of refractive surgery. 3- Patients with diabetic retinal vasculopathy or retinal detachment. 4- Patients with chronic angle closure glaucoma, open angle glaucoma or 2ry glaucoma

Sponsors & Collaborators

• Minia University: lead

Study Sites (1)

mohamed Mahmoud

Minya, Minya Governorate, 61111, Egypt

RECRUITING

MeSH Terms

Conditions

Glaucoma, Angle-Closure

Condition Hierarchy (Ancestors)

Glaucoma; Ocular Hypertension; Eye Diseases

Study Officials

• mohamed Salah

  Minia faculty of medicine

  PRINCIPAL INVESTIGATOR

Central Study Contacts

mohamed Salah

CONTACT

01003321802; drmsalah1982@yahoo.com

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 28, 2022
• First Posted: April 18, 2022
• Study Start: January 11, 2022
• Primary Completion: December 1, 2022
• Study Completion: December 1, 2022
• Last Updated: April 18, 2022

Record last verified: 2022-04

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)