Outcome of GATT Combined With Goniosynechiolysis in Glaucoma Patients With Secondary Synechial Angle Closure.

NCT06445634 | Recruiting

• 1 other identifier: _MD-393-2023_
• Study Type: interventional
• Target: 23
• Locations: 1 country
• Sites: 1

Brief Summary

To evaluate the intraocular pressure reduction effect of combined gonioscopy-assisted transluminal trabeculotomy (GATT) with goniosynechialysis in eyes with secondary synechial angle closure glaucoma.

Conditions

Glaucoma, Angle-Closure

Keywords

secodary angle closure; GATT; intra ocular pressure

Outcome Measures

Primary Outcomes (2)

• IOP and glaucoma medications.

  measurement of intra ocular pressure and documentation of number of anti glaucoma medications post operative

  1day,1 week,1 months, 3 months, 6 months and 1 year

• Surgical success.

  Surgical success will be defined as: complete if IOP is less than or equal to 21mmHg without medications and qualified success if IOP is less than or equal to 21mmHg with medications. Failure will be the inability to achieve such a pressure, the need for another glaucoma operation or the development of a sight-threatening complication (e.g., retinal detachment, endophthalmitis)

  1day,1 week,1 months, 3 months, 6 months and 1 year

Secondary Outcomes (1)

• Complications.

  1day,1 week,1 months, 3 months, 6 months and 1 year

Study Arms (1)

Gatt combined with goinosynechiolysis in secondary synechial angle closure

OTHER

Outcome of Gonioscopy-Assisted Transluminal Trabeculotomy Combined with Goniosynechiolysis in Glaucoma Patients with Secondary Synechial Angle Closure

Other: Gonioscopy-Assisted Transluminal Trabeculotomy Combined with Goniosynechiolysis

Interventions

Gonioscopy-Assisted Transluminal Trabeculotomy Combined with Goniosynechiolysis OTHER

Gonioscopy-Assisted Transluminal Trabeculotomy Combined with Goniosynechiolysis in Glaucoma Patients with Secondary Synechial Angle Closure

Also known as: GATT

Gatt combined with goinosynechiolysis in secondary synechial angle closure

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Patients with secondary synechial angle closure glaucoma
• Involving more than 180 degrees of the iridocorneal angle
• Requiring surgery for uncontrolled IOP despite maximum tolerated therapy.

You may not qualify if:

• Eyes with PACG.
• Eyes with neovascular glaucoma. (Some apparently stable NVG cases would have remnants of neo-vessels in the angle that are hidden behind the synechiae).
• Eyes with retinal pathology.
• Eyes requiring combined phacoemulsification and GATT.
• Eyes with corneal pathology that can preclude surgery and imaging.

Sponsors & Collaborators

• Kasr El Aini Hospital: lead

Study Sites (1)

Kasralainy Hospitals

Giza, 11555, Egypt

RECRUITING

MeSH Terms

Conditions

Glaucoma, Angle-Closure

Condition Hierarchy (Ancestors)

Glaucoma; Ocular Hypertension; Eye Diseases

Central Study Contacts

Rokaya Radwan

CONTACT

01066471468; rokaia.e.radwan@students.kasralainy.edu.eg

Fayrouz Aboalazaym

CONTACT

01007419500; fayrouzaboalazaym@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principal investigator

Model Details: prospective cohort

Study Record Dates

• First Submitted: May 31, 2024
• First Posted: June 6, 2024
• Study Start: April 1, 2024
• Primary Completion: August 1, 2025
• Study Completion: August 1, 2025
• Last Updated: June 6, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF
• Time Frame: After publication within 18 months
• Access Criteria: will be uploaded

Locations

EG (1)