NCT05317910

Brief Summary

This clinical trial evaluates the impact of music interventions on caregivers of patients with memory disorders, Alzheimer's disease, dementia and related disorders. This study will follow caregivers of patients within the rehabilitation day care hospital "Memory and Frailty" (Hôpital de Jour de Réadaptation Mémoire et Fragilités), Sainte-Marie Paris Hospital.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at below P25 for not_applicable alzheimer-disease

Timeline
Completed

Started Apr 2022

Shorter than P25 for not_applicable alzheimer-disease

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 13, 2022

Completed
19 days until next milestone

Study Start

First participant enrolled

April 1, 2022

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 8, 2022

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 20, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2022

Completed
Last Updated

July 27, 2022

Status Verified

July 1, 2022

Enrollment Period

4 months

First QC Date

March 13, 2022

Last Update Submit

July 26, 2022

Conditions

Keywords

Music interventionAlzheimerAnxiety

Outcome Measures

Primary Outcomes (1)

  • Change from baseline STAI score at 28 days

    Long-term anxiety will be measured using the State Trait Anxiety Inventory (STAI) scale. The STAI is a psychological inventory based on a 4-point Likert scale and consists of 40 questions on a self-report basis. The STAI measures two types of anxiety - state anxiety, or anxiety about an event, and trait anxiety, or anxiety level as a personal characteristic. Scores range from 20 to 80, with higher scores correlating with greater anxiety.

    Day 1 and Day 28

Secondary Outcomes (2)

  • Change on EVA score immediately after each session

    Before and immediately after each session (up to 28 days (one session every day))

  • Change from baseline STAI score at 15 days

    Day 1 and Day 15

Study Arms (1)

Music intervention

EXPERIMENTAL

Music intervention (duration 20 minutes) every day for 30 days

Other: MUSIC CARE

Interventions

Relaxation-type receptive musical intervention technique. The standardized 20-minute musical sequence is broken down into several phases that gradually lead the patient to relaxation using the new U-Mount technique \[1, 2\] (Figure 1). The effect works by reducing the musical rhythm, orchestral formation, frequencies and volume (the "U" descending phase). After a maximum relaxation phase (lower part of the "U"), a re-activating phase (ascending branch of the "U") is followed.

Music intervention

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Anxiety Self-Assessment Score (STAI) greater than 46 at Day 1
  • Patient relationship (child, spouse, brother/sister)

You may not qualify if:

  • Presence of a psychiatric disorder
  • Intellectual disability
  • Major hearing loss
  • Professional musician

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sainte-Marie Hospital

Paris, 75014, France

Location

MeSH Terms

Conditions

Alzheimer DiseaseAnxiety Disorders

Condition Hierarchy (Ancestors)

DementiaBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative DiseasesNeurocognitive DisordersMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 13, 2022

First Posted

April 8, 2022

Study Start

April 1, 2022

Primary Completion

July 20, 2022

Study Completion

July 20, 2022

Last Updated

July 27, 2022

Record last verified: 2022-07

Locations