NCT05294575

Brief Summary

This study evaluates data from patients in The Danish Medical Service electronical registry over a 6-year period from 2016 to 2021 with traumatic cardiac arrest. The objective of this study is to use artificial intelligence to evaluate reversible causes and relevant circumstances regarding traumatic OHCA in order to improve treatment and survival.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
31,200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 22, 2022

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

February 24, 2022

Completed
28 days until next milestone

First Posted

Study publicly available on registry

March 24, 2022

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2023

Completed
Last Updated

March 24, 2022

Status Verified

March 1, 2022

Enrollment Period

10 months

First QC Date

February 24, 2022

Last Update Submit

March 16, 2022

Conditions

Out-Of-Hospital Cardiac ArrestTrauma

Keywords

Out-of-Hospital Cardiac ArrestTraumatic Cardiac ArrestCardiopulmonary ResuscitationEmergency Medical Service

Outcome Measures

Primary Outcomes (2)

  • Survival to hospital admission

    Status at admission.

    The timeframe is at the time of hospital admission, therefore no specific time point (ie 24-hours, 1hour ect) can be stated

  • Longterm Survival

    30-day survival

    30-day

Secondary Outcomes (1)

  • Return Of Spontaneous Circulation

    The timeframe is from incident (at scene) to discharge from admission to hospital. As of such it is not meassured at any specific time or time point..

Study Arms (2)

OHCA in the general population

All Out-of-Hospital Cardiac Arrests

Traumatic OHCA

OHCA related to Trauma

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

This registry based research evaluates traumatic OHCA in the general population of Denmark based on the national registry of cardiac arrests in Denmark.

You may qualify if:

  • OHCA related to trauma

You may not qualify if:

  • All other causes of OHCA

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Prehospital Center

Næstved, Denmark

Location

Related Publications (6)

  • Lott C, Truhlar A, Alfonzo A, Barelli A, Gonzalez-Salvado V, Hinkelbein J, Nolan JP, Paal P, Perkins GD, Thies KC, Yeung J, Zideman DA, Soar J; ERC Special Circumstances Writing Group Collaborators. European Resuscitation Council Guidelines 2021: Cardiac arrest in special circumstances. Resuscitation. 2021 Apr;161:152-219. doi: 10.1016/j.resuscitation.2021.02.011. Epub 2021 Mar 24.

    PMID: 33773826BACKGROUND

  • Kleber C, Giesecke MT, Lindner T, Haas NP, Buschmann CT. Requirement for a structured algorithm in cardiac arrest following major trauma: epidemiology, management errors, and preventability of traumatic deaths in Berlin. Resuscitation. 2014 Mar;85(3):405-10. doi: 10.1016/j.resuscitation.2013.11.009. Epub 2013 Nov 25.

    PMID: 24287328BACKGROUND

  • Lindskou TA, Mikkelsen S, Christensen EF, Hansen PA, Jorgensen G, Hendriksen OM, Kirkegaard H, Berlac PA, Sovso MB. The Danish prehospital emergency healthcare system and research possibilities. Scand J Trauma Resusc Emerg Med. 2019 Nov 4;27(1):100. doi: 10.1186/s13049-019-0676-5.

    PMID: 31684982BACKGROUND

  • Leis CC, Hernandez CC, Blanco MJ, Paterna PC, Hernandez Rde E, Torres EC. Traumatic cardiac arrest: should advanced life support be initiated? J Trauma Acute Care Surg. 2013 Feb;74(2):634-8. doi: 10.1097/TA.0b013e31827d5d3c.

    PMID: 23354262RESULT

  • Evans CC, Petersen A, Meier EN, Buick JE, Schreiber M, Kannas D, Austin MA; Resuscitation Outcomes Consortium Investigators. Prehospital traumatic cardiac arrest: Management and outcomes from the resuscitation outcomes consortium epistry-trauma and PROPHET registries. J Trauma Acute Care Surg. 2016 Aug;81(2):285-93. doi: 10.1097/TA.0000000000001070.

    PMID: 27070438RESULT

  • Pfeifer R, Tarkin IS, Rocos B, Pape HC. Patterns of mortality and causes of death in polytrauma patients--has anything changed? Injury. 2009 Sep;40(9):907-11. doi: 10.1016/j.injury.2009.05.006. Epub 2009 Jun 21.

    PMID: 19540488RESULT

MeSH Terms

Conditions

Out-of-Hospital Cardiac ArrestWounds and Injuries

Condition Hierarchy (Ancestors)

Heart ArrestHeart DiseasesCardiovascular Diseases

Study Officials

  • signe A Wolthers, MD

    Prehospital Center, Næstved, Region Zealand, Denmark

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, Principal Investigator

Study Record Dates

First Submitted

February 24, 2022

First Posted

March 24, 2022

Study Start

February 22, 2022

Primary Completion

January 1, 2023

Study Completion

January 1, 2023

Last Updated

March 24, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will share
Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Upon request. Data will be available for one year from the date.

Locations

DK(1)