NCT05242523

Brief Summary

This study aims at establishing a laboratory experiment that mimics office work stressors, examining the feasibility of automated stress detection, and identifying the most significant physiological and/or behavioral features that can be used to differentiate between positive stress (eustress) and negative stress (distress). Additionally, we will investigate if triggering the olfactory (exposing participants to pleasant smells) senses would help reduce stress.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 20, 2022

Completed
27 days until next milestone

First Posted

Study publicly available on registry

February 16, 2022

Completed
1 month until next milestone

Study Start

First participant enrolled

April 1, 2022

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 5, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 5, 2022

Completed
Last Updated

July 8, 2022

Status Verified

July 1, 2022

Enrollment Period

3 months

First QC Date

January 20, 2022

Last Update Submit

July 7, 2022

Conditions

Outcome Measures

Primary Outcomes (4)

  • Heart rate

    Heart rate will be collected through a sensor attached to the participant's chest at a collection rate of 1 heart rate reading per second. The average heart rate will be examined across study conditions.

    Throughout study participation, up to 120 minutes

  • Electrodermal activity

    Electrodermal activity will be collected through a sensor placed on the wrist similar to a watch, with data collection at a rate of 4 readings per second. The average electrodermal activity will be examined across study conditions.

    Throughout study participation, up to 120 minutes

  • Blink rate

    A facial detection algorithm will be used to detect the blinking rate of the participant from a camera that collects 10 frames per second. The average blink rate will be examined across study conditions.

    Throughout study participation, up to 120 minutes

  • Gaze angle

    A facial detection algorithm will be used to detect the gaze angle direction of the participant from a camera that collects 10 frames per second. The durations of gaze angles will be examined across study conditions.

    Throughout study participation, up to 120 minutes

Secondary Outcomes (2)

  • Mouse clicks

    Throughout study participation, up to 120 minutes

  • Keyboard keystrokes

    Throughout study participation, up to 120 minutes

Study Arms (3)

Control

NO INTERVENTION

No exposure to smells.

Olfactory Condition - 1

EXPERIMENTAL

Participants in this condition will be exposed to the smell of natural wood scent continuously. A diffuser with essential oils will be turned on during that time to deliver the smell.

Other: Natural wood scent

Olfactory Condition - 2

EXPERIMENTAL

Participants in this condition will be exposed to the smell of Bergamot scent continuously. A diffuser with essential oils will be turned on during that time to deliver the smell.

Other: Bergamot scent

Interventions

The scent of bergamot is fruity and citrusy, with floral hints and spice notes.

Olfactory Condition - 2

Wood notes tend to be rich and warm, often forming the base of a scent due to their aromatic weight.

Olfactory Condition - 1

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Participants will be older than 18.
  • Participants should be proficient at speaking and writing in English.
  • Qualified participants should have a normal or corrected-to-normal vision, and a normal sense of smell.

You may not qualify if:

  • Participants will be screened to make sure that they don't have any physical or psychological-related problems that make them sensitive to stress-inducing tasks.
  • Participants who are taking any medication to regulate their blood pressure will not be allowed to participate in the study as these medications might affect the quality of the blood volume pulse-related data.
  • Pregnant women are not allowed to participate in this study.
  • Participants using prescription medication, diagnosed with color blindness, rhinitis, or hay fever, or have allergic reactions to essential oils ( e.g., contact dermatitis, allergic rhinitis) will not be allowed to participate in this study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Southern California

Los Angeles, California, 90089, United States

Location

Study Officials

  • Burcin Becerik-Gerber, PhD

    University of Southern California

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
DIAGNOSTIC
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

January 20, 2022

First Posted

February 16, 2022

Study Start

April 1, 2022

Primary Completion

July 5, 2022

Study Completion

July 5, 2022

Last Updated

July 8, 2022

Record last verified: 2022-07

Data Sharing

IPD Sharing
Will not share

Locations