Upper Cervical and Thoracic Chiropractic Adjustment

NCT05465395 | Suspended

• 1 other identifier: I-0020
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The proposed study examines the differences in how the ANS responds to cervical adjustments in comparison to thoracic adjustments. This study is the continuation of a previous study titled Perceived stress and patterns of autonomic function: a protocol development study. Autonomic tests such as HRV, GSR, and the stress surveys will be the primary method of measurement. CareTaker and Biopac devices will provide continual data collection of ECG (for HRV analysis) and GSR throughout the exam and adjustment. Participant's subjective stress levels will be measured through the use of stress questionnaires including the National Stressful Events Survey Acute Stress Disorder Short Scale, the Hamilton Anxiety Rating Scale, and the Connor-Davidson Resilience Scale. The objective of the study is to determine if the location of a chiropractic adjustment will affect the autonomic nervous system in such a way that PNS or SNS activation increases or decreases after the adjustment. Further, the study will continue to examine how the chiropractic adjustment affects the subjective stress response.

Conditions

Stress

Keywords

Heart Rate Varability; Autonomic Nervious System; Chiropractic Adjustment

Outcome Measures

Primary Outcomes (5)

• Caretaker Heart Rate Variability

  HRV allows for an understanding of Autonomic (parasympathetic) function, via measuring the interval of R peaks in QRS complexes.

  Through study completion, an average of 1 week

• Galvanic Skin Response

  Galvanic Skin response gives a strong measure of Sympathetic response via electrical conductivity of perspiration.

  Through study completion, an average of 1 week

• Hamilton Anxiety Rating Scale

  Measures the severity of anxiety symptoms

  Through study completion, an average of 1 week

• NSESSS

  Measures PTSD symptoms in people 18 and up.

  Through study completion, an average of 1 week

• CD-RISC-25

  Measure of adaptability

  Through study completion, an average of 1 week

Study Arms (2)

Upper Cervical Adjustment

EXPERIMENTAL

Upper cervical adjustemnt

Procedure: Upper Cervical Adjustemnt; Procedure: Thoracic Adjustemnt

Thoracic Adjustment

ACTIVE COMPARATOR

Thoracic adjustment

Procedure: Upper Cervical Adjustemnt; Procedure: Thoracic Adjustemnt

Interventions

Upper Cervical Adjustemnt PROCEDURE

Upper cervical adjustement

Thoracic Adjustment; Upper Cervical Adjustment

Thoracic Adjustemnt PROCEDURE

Thoracic adjustment

Thoracic Adjustment; Upper Cervical Adjustment

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Over the age of 19
• In good health
• Willing to have blood pressure taken
• Willinig to shave a small area of chest hair for placement of a ECG patch
• Consent to a physical exam
• Consent ot chiropractic evaluationa nd 2 adjustments

Sponsors & Collaborators

• Life University: lead

Study Sites (1)

Dr. Sid E. Williams Center for Chiropractic Research

Atlanta, Georgia, 30308, United States

Location

Study Officials

• Stephanie Sullivan

  Life Univeristy

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 7, 2022
• First Posted: July 19, 2022
• Study Start: October 12, 2021
• Primary Completion: November 1, 2023
• Study Completion: November 1, 2023
• Last Updated: May 3, 2023

Record last verified: 2023-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)